US6433159B1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Compositions and methods for treatment of Hepatitis C virus associated diseases
Assignee: Ionis Pharmaceuticals Inc
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Filing: 1997-03-17
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Granted: 2002-08-13
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Expires: 2017-03-17
Abstract
Abstract Antisense oligonucleotides are provided which are complementary to at least a portion of HCV RNA and specifically hybridizable therewith. These oligonucleotides can be administered to inhibit the replication of Hepatitis C virus in vivo or in vitro and to treat Hepatitis C virus-associated disease. These compounds can be used either prophylactically or therapeutically to reduce the severity of diseases associated with Hepatitis C virus.
Inventors
- 👤 Kevin P. Anderson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 12:00
CPC Classifications
C; C12; C12N; C12N15/00; C12N15/09; C12N15/11; C12N15/113; C12N15/1131; C07; C07H; C07H21/00; C07K; C07K14/00; C07K14/005; C12Q; C12Q1/00; C12Q1/70; C12Q1/701; C12Q1/706; C12Q1/707; C12N2310/00; C12N2310/30; C12N2310/31; C12N2310/315; C12N2310/33; C12N2310/35; C12N2310/352; C12N2310/3521; C12N2310/3527; C12N2770/00; C12N2770/00011; C12N2770/24011; C12N2770/24211; C12N2770/24222
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
38 words
An oligonucleotide 12-25 nucleotides in length which has a nucleotide sequence complementary to at least a portion of a polyprotein translation initiation region of HCV genomic or messenger RNA, said oligonucleotide which inhibits the translation of said RNA.
Claim 2
Dependent Claim
38 words
An oligonucleotide 12-25 nucleotides in length which has a nucleotide sequence complementary to at least a portion of a polyprotein translation initiation region of HCV genomic or messenger RNA, said oligonucleotide which inhibits the translation of said RNA.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2005-08-12 | 2006-02-11 | 2006-08-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2009-08-12 | 2010-02-11 | 2010-08-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2013-08-12 | 2014-02-11 | 2014-08-13 | $7700.00 | Window Closed / Lapsed |