US6400151B1 — Method and apparatus for the acquisition of data …

Claim 1

Independent Claim 175 words

A method for the acquisition of data for an image representation showing the spatial distribution of the magnetic resonance behavior of an object within a selected localized region comprising the steps of: arranging the object in a stationary magnetic field; exposing the object to a succession of high frequency pulses and pulses of magnetic field gradients in different spatial directions in such manner that a succession of magnetic resonance signals appears wherein said succession of high frequency pulses and pulses of magnetic field gradients comprises at least two different sequences of high frequency pulses and magnetic field gradient pulses which differ in at least one of the features of the signal production responsible for different aspects of the image quality and wherein these sequences are carried out after one another in time; reading said magnetic resonance signals by scanning under the influence of respective read gradients and using said signals as data sets for the filling a K-space, and, entering the magnetic resonance signals read out for different sequences into different bands of the K-space.

Claim 2

Independent Claim 175 words

A method for the acquisition of data for an image representation showing the spatial distribution of the magnetic resonance behavior of an object within a selected localized region comprising the steps of: arranging the object in a stationary magnetic field; exposing the object to a succession of high frequency pulses and pulses of magnetic field gradients in different spatial directions in such manner that a succession of magnetic resonance signals appears wherein said succession of high frequency pulses and pulses of magnetic field gradients comprises at least two different sequences of high frequency pulses and magnetic field gradient pulses which differ in at least one of the features of the signal production responsible for different aspects of the image quality and wherein these sequences are carried out after one another in time; reading said magnetic resonance signals by scanning under the influence of respective read gradients and using said signals as data sets for the filling a K-space, and, entering the magnetic resonance signals read out for different sequences into different bands of the K-space.

Claim 3

Dependent Claim 90 words

Method according to claim 1 , wherein the step of exposing the object to a succession of high frequency pulses and pulses of magnetic field gradients comprises the steps of selecting, a sequence of high frequency pulses and magnetic field gradient pulses which emphasizes a desired aspect of image quality and wherein the signals scanned therefrom are collated in the middle band of the K-space, and, in order to fill the remaining part of the K-space, using one or more other sequences which lay less emphasis on the particular aspect.

Claim 4

Dependent Claim 90 words

Method according to claim 1 , wherein the step of exposing the object to a succession of high frequency pulses and pulses of magnetic field gradients comprises the steps of selecting, a sequence of high frequency pulses and magnetic field gradient pulses which emphasizes a desired aspect of image quality and wherein the signals scanned therefrom are collated in the central band of the K-space, and, in order to fill the remaining part of the K-space, using one or more more rapid sequences, even if emphasizing the particular aspect less.

Claim 5

Dependent Claim 64 words

Method according to claim 1 , wherein the step of entering the magnetic resonance signals into different bands of the K-space comprises the step of filling the middle band of the K-space with the scan values of gradient echoes which are produced by a train of high frequency excitation pulses with flip angles of less than 90° and a repetition time <<T 1 .

Claim 6

Dependent Claim 45 words

Method according to claim 4 , comprising the additional step of subsequently filling the remaining part of the K-space with scanned values of magnetic resonance signals which are produced by refocusing of the previously produced gradient echoes by means of a refocusing high frequency pulse.

Claim 7

Dependent Claim 38 words

Method according to claim 4 , comprising the additional step of subsequently filling the remaining part of the K-space with scanned values of magnetic resonance signals which are produced by a following series of refocusing high frequency pulses.

Claim 8

Dependent Claim 59 words

Method according to claim 1 wherein the step of exposing the object to a succession of high frequency pulses and pulses of magnetic field gradients comprises the steps of filling the middle band of the K-space with scanned values of spin echo signals which are produced by an excitation pulse and a following series of refocusing high frequency pulses.

Claim 9

Dependent Claim 42 words

Method according to claim 4 , comprising the additional step of subsequently filling the remaining part of the K-space with scanned values from gradient echoes which are produced by multiple polarity reversal of the read gradient after a high frequency excitation pulse.

Claim 10

Dependent Claim 60 words

Method according to claim 1 wherein the step of exposing the object to a succession of high frequency pulses and pulses of magnetic field gradients comprises the steps of filling the middle band of the K-space with the scanned values from gradient echoes which are produced by multiple polarity reversal of the read gradient after a high frequency excitation pulse.

Claim 11

Dependent Claim 36 words

Method according to claim 9 , comprising the additional step of subsequently filling the remaining part of the K-space with scanned values from signals which are produced by a following train of refocusing high frequency pulses.

Claim 12

Dependent Claim 34 words

Method according to claim 7 , comprising the additional step of subsequently filling the remaining part of the K-space with scanned values from gradient echoes which are produced respectively after high frequency excitation pulses.

Claim 13

Dependent Claim 51 words

Method according to claim 4 , comprising the additional step of subsequently filling the remaining part of the K-space with scanned values from echoes which are produced by a series of exciting or refocusing high frequency pulses, between which echo signals are produced by multiple polarity reversal of the read gradient.

Claim 14

Dependent Claim 16 words

Method according to claim 1 , wherein the K-space to be filled is two-dimensional or multidimensional.

Claim 15

Dependent Claim 41 words

Method according to claim 1 , wherein the step of entering the magnetic resonance signals into different bands of the K-space comprises the step of following trajectories which correspond to other paths than the course of the lines of the K-space.

Claim 16

Dependent Claim 19 words

Method according to claim 1 , wherein different sequences with different bandwidths of the echo scanning are read out.

Claim 17

Dependent Claim 38 words

Method according to claim 1 , comprising the additional step of obtaining a preliminary magnetic resonance sequence before exposing the object to a succession of high frequency pulses and pulses of magnetic field gradients in different spatial directions.

Claim 18

Dependent Claim 67 words

Method according to claim 16 , wherein said preliminary magnetic resonance sequence comprises a suitable combination of high frequency pulses and magnetic field gradient pulses to produce an image contrast on the basis of T 1 , T 1 e, T 2 , T 2 *, flow or diffusion or in order to produce a magnetisation transfer contrast (MTC) or in order to suppress fat or water.

Claim 19

Dependent Claim 233 words

Apparatus for the acquisition of data for an image representation which shows the spatial distribution of magnetic resonance behavior of an object within a selected localised region, comprising means ( 11 , 21 ) for producing a homogeneous magnetic field in the object region to be investigated, which directs the spin in the field direction, means ( 15 , 23 ) for producing high frequency pulses which act on the object region, means ( 12 , 13 , 14 , 22 ) for producing magnetic field gradients in different spatial directions, means ( 40 , 50 ) for reading out the magnetic resonance echo signals arising from the object region in respnse to the high frequency pulses and magnetic field gradients and writing these echo signals into the K-space, and a control means ( 30 ) for controlling the means producing the high frequency pulses and the means producing the magnetic field gradients and the readout means such that the object region is subjected to a succession of at least two different sequences of high frequency pulses and magnetic field gradient pulses in order to produce different sequences of magnetic resonance echo signals which differ in at least one of the features of the echo production which are responsible for different aspects of image quality, and that the echo signals of the different sequences are written into respective different bands of the K-space.

Claim 20

Dependent Claim 233 words

Apparatus for the acquisition of data for an image representation which shows the spatial distribution of magnetic resonance behavior of an object within a selected localised region, comprising means ( 11 , 21 ) for producing a homogeneous magnetic field in the object region to be investigated, which directs the spin in the field direction, means ( 15 , 23 ) for producing high frequency pulses which act on the object region, means ( 12 , 13 , 14 , 22 ) for producing magnetic field gradients in different spatial directions, means ( 40 , 50 ) for reading out the magnetic resonance echo signals arising from the object region in respnse to the high frequency pulses and magnetic field gradients and writing these echo signals into the K-space, and a control means ( 30 ) for controlling the means producing the high frequency pulses and the means producing the magnetic field gradients and the readout means such that the object region is subjected to a succession of at least two different sequences of high frequency pulses and magnetic field gradient pulses in order to produce different sequences of magnetic resonance echo signals which differ in at least one of the features of the echo production which are responsible for different aspects of image quality, and that the echo signals of the different sequences are written into respective different bands of the K-space.

Annuity Stage	Window Opens	Payment Deadline	Surcharge Period Until	Estimated Fee	Status
3.5 Years (Year 4)	2005-06-03	2005-12-03	2006-06-04	$2000.00	Window Closed / Lapsed
7.5 Years (Year 8)	2009-06-03	2009-12-03	2010-06-04	$3760.00	Window Closed / Lapsed
11.5 Years (Year 12)	2013-06-03	2013-12-03	2014-06-04	$7700.00	Window Closed / Lapsed

Method and apparatus for the acquisition of data for magnetic resonance imaging

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