US6399760B1
Expired / Lapsed
US
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RP compositions and therapeutic and diagnostic uses therefor
Assignee: Millennium Pharmaceuticals Inc
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Filing: 1996-08-29
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Granted: 2002-06-04
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Expires: 2016-08-29
Abstract
Abstract The present invention, which is based on the discovery of novel genes encoding rp polypeptides, features therapeutics, diagnostics and screening assays.
Inventors
- 👤 Carlos J. Gimeno
- 👤 Patrick W. Kleyn
- 👤 Karen J. Moore
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 10:28
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/575; C07K14/5759; A; A61; A61K; A61K38/00; A61K48/00
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
19 words
An isolated nucleic acid molecule encoding the amino acid sequence of SEQ ID NO:2, or a full complement thereof.
Claim 2
Dependent Claim
19 words
An isolated nucleic acid molecule encoding the amino acid sequence of SEQ ID NO:2, or a full complement thereof.
Claim 3
Dependent Claim
18 words
An isolated nucleic acid molecule comprising the nucleotide sequence of SEQ ID NO:1, or a full complement thereof.
Claim 4
Dependent Claim
18 words
An isolated nucleic acid molecule comprising the nucleotide sequence of SEQ ID NO:1, or a full complement thereof.
Claim 5
Dependent Claim
18 words
An isolated nucleic acid molecule comprising the nucleotide sequence of SEQ ID NO:3, or a full complement thereof.
Claim 6
Dependent Claim
18 words
An isolated nucleic acid molecule comprising the nucleotide sequence of SEQ ID NO:3, or a full complement thereof.
Claim 7
Dependent Claim
31 words
An isolated nucleic acid molecule comprising the nucleotide sequence of the DNA insert of the plasmid deposited with American Type Culture Collection as Accession Number 98144, or a full complement thereof.
Claim 8
Dependent Claim
31 words
An isolated nucleic acid molecule comprising the nucleotide sequence of the DNA insert of the plasmid deposited with American Type Culture Collection as Accession Number 98144, or a full complement thereof.
Claim 9
Dependent Claim
31 words
An isolated nucleic acid molecule comprising the nucleotide sequence of the DNA insert of the plasmid deposited with American Type Culture Collection as Accession Number 98147, or a full complement thereof.
Claim 10
Dependent Claim
31 words
An isolated nucleic acid molecule comprising the nucleotide sequence of the DNA insert of the plasmid deposited with American Type Culture Collection as Accession Number 98147, or a full complement thereof.
Claim 11
Dependent Claim
19 words
An isolated nucleic acid molecule encoding the amino acid sequence of SEQ ID NO:5, or a full complement thereof.
Claim 12
Dependent Claim
19 words
An isolated nucleic acid molecule encoding the amino acid sequence of SEQ ID NO:5, or a full complement thereof.
Claim 13
Dependent Claim
18 words
An isolated nucleic acid molecule comprising the nucleotide sequence of SEQ ID NO:6, or a full complement thereof.
Claim 14
Dependent Claim
18 words
An isolated nucleic acid molecule comprising the nucleotide sequence of SEQ ID NO:6, or a full complement thereof.
Claim 15
Dependent Claim
27 words
A vector comprising the nucleic acid molecule of any one of claims 1 , 2 , 3 , 4 , 5 , 6 , or 7 .
Claim 16
Dependent Claim
37 words
An isolated nucleic, acid molecule comprising the nucleic acid molecule of any one of claims 1 , 2 , 3 , 4 , 5 , 6 or 7 and a nucleic acid sequence encoding a heterologous polypeptide.
Claim 17
Dependent Claim
30 words
An isolated host-cell which is transfected with the nucleic acid molecule of any one of claims 1 , 2 , 3 , 4 , 5 , 6 or 7 .
Claim 18
Dependent Claim
12 words
The host cell of claim 10 which is a mammalian host cell.
Claim 19
Dependent Claim
29 words
A method for expressing a polypeptide comprising culturing the isolated host cell of claim 11 under conditions in which the nucleic acid molecule is expressed, thereby expressing said polypeptide.
Claim 20
Dependent Claim
29 words
A kit comprising a nucleic acid molecule of any one of claims 1 , 2 , 3 , 4 , 5 , 6 or 7 and instructions for use.
Claim 21
Dependent Claim
26 words
A composition comprising the nucleic acid molecule of any one of claims 1 , 2 , 3 , 4 , 5 , 6 or 7 .
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2005-06-03 | 2005-12-03 | 2006-06-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2009-06-03 | 2009-12-03 | 2010-06-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2013-06-03 | 2013-12-03 | 2014-06-04 | $7700.00 | Window Closed / Lapsed |