US6302913B1
Expired / Lapsed
US
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Biomaterial and bone implant for bone repair and replacement
Assignee: Technology Finance Corp Pty Ltd
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Filing: 1995-05-24
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Granted: 2001-10-16
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Expires: 2015-05-24
Abstract
Abstract This invention relates to a biomaterial useful in bone repair and replacement, and to implants for cranofacial, orthopaedic, and especially dental applications. The implants have a unique geometric configuration, their surfaces defining concavities having a shape and dimensions which induce or enhance the rate and/or amount of bone growth at the implant site. The biomaterial preferably has a specific porous configuration and the implant may be at least coated with such a biomaterial of hydroxyapatite, for example.
Inventors
- 👤 Ugo Ripamonti
- 👤 Anthony Nigel Kirkbride
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 22:34
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/28; A61C; A61C8/00; A61C8/0012; A61L; A61L27/00; A61L27/02; A61L27/12; A61C8/0013; A61F2/2875; A61F2/30; A61F2/30721; A61F2/30749; A61F2/30767; A61F2002/30001; A61F2002/30108; A61F2002/30199; A61F2002/30224; A61F2/30771; A61F2002/30795; A61F2/3094; A61F2/30942; A61F2002/30957; A61F2002/30968; A61F2220/00; A61F2220/0008; A61F2230/00; A61F2230/0063; A61F2230/0069; A61F2310/00; A61F2310/00005; A61F2310/00011; A61F2310/00023; A61F2310/00179; A61F2310/00293; A61F2310/00389; A61F2310/00592; A61F2310/00796; A61L2430/00; A61L2430/02
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
80 words
A bone implant for implanting into a subject at a site where bone growth is required, the implant comprising a body of sintered bioactive ceramic biomaterial, the body having intrinsic osteoinductive activity and having a network of interconnected coalesced rounded inner porous spaces as well as surface concavities of the body interconnected with the porous spaces, wherein the rounded inner porous spaces consist essentially of substantially spherical or spheroidal shaped spaces having diameter of between 300 μm and 3000 μm.
Claim 2
Dependent Claim
80 words
A bone implant for implanting into a subject at a site where bone growth is required, the implant comprising a body of sintered bioactive ceramic biomaterial, the body having intrinsic osteoinductive activity and having a network of interconnected coalesced rounded inner porous spaces as well as surface concavities of the body interconnected with the porous spaces, wherein the rounded inner porous spaces consist essentially of substantially spherical or spheroidal shaped spaces having diameter of between 300 μm and 3000 μm.
Claim 3
Dependent Claim
44 words
A bone implant according to claim 1 , wherein the surface concavities consist essentially of concavities having a diameter of about 200 μm to 3000 μm, and a depth of 200 μm to 3000 μm, thereby enhancing the intrinsic osteoinductive activity of the body.
Claim 4
Dependent Claim
25 words
A bone implant according to claim 1 , wherein the biomaterial is sintered hydroxyapatite, and has native or recombinant human bone morphogenetic proteins adsorbed therein.
Claim 5
Dependent Claim
22 words
A bone implant according to claim 1 , wherein the outer surface of the body has been treated with a liquid etchant.
Claim 6
Dependent Claim
64 words
A method of inducing or enhancing the rate and/or amount of bone growth in a subject, in a site where bone growth is desired, which method includes: selecting a bone implant according to claim 1 , and having an appropriate overall shape and size for accommodation in the site; and placing the implant into the subject in the site where bone growth is desired.
Claim 7
Dependent Claim
20 words
A bone implant according to claim 1 , wherein the biomaterial has native or recombinant bone morphogenic proteins adsorbed therein.
Claim 8
Dependent Claim
14 words
A bone implant according to claim 1 , wherein the biomaterial is sintered hydroxyapatite.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2004-10-15 | 2005-04-16 | 2005-10-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2008-10-15 | 2009-04-16 | 2009-10-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2012-10-15 | 2013-04-16 | 2013-10-16 | $7700.00 | Window Closed / Lapsed |