← Back to Patent Explorer
US4629464A Expired / Lapsed US ⏱️ 0.0 years remaining

Porous hydroxyapatite material for artificial bone substitute

Assignee: TDK Corp
•
Filing: 1985-08-29
•
Granted: 1986-12-16
•
Expires: 2005-08-29
📄 Original PDF 🌐 Google Patents 🔄 Sync Now

Abstract

Abstract The sintered microporous hydroxyapatite material of the invention is useful as an artificial bone substitute material either in a granular and slurried from in a physiological saline solution used as a filling material for lost portions or cavities of bones or in a form of a shaped prosthetic bone substitute member. The inventive material is characteristic in the open pore structure of micropores with a pore diameter distribution in the range from 0.01 to 0.10 mm and a porosity in the range from 20 to 50%. When the material is used in the form of a granular bone filling, the particle diameter thereof should be in the range from 0.1 to 2.0 mm. When the material is used as the prosthetic bone substitute member, the shaped body should be formed of the matrix of the inventive microporous material and pores with a pore diameter distribution in the range from 0.2 to 2.0 mm. When an increased bending strength is desired, the prosthetic member should preferably have a core-and-crust structure of which the matrix of the core portion and the crust layer having a thickness of 0.1 to 2 mm are formed of the inventive microporous material, the core portion being formed of the matrix and pores of 0.2 to 2.0 mm diameter distribution throughout the matrix.

Inventors

  • 👤 Susumu Takata
  • 👤 Shoichi Wakabayashi
  • 👤 Hiroyasu Noma
  • 👤 Tatsuya Wakatsuki

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 16:52
CPC Classifications
C; C04; C04B; C04B38/00; C04B38/0051; A; A61; A61F; A61F2/00; A61F2/02; A61F2/28; A61F2/30; A61F2/30767; A61L; A61L27/00; A61L27/02; A61L27/12; A61L27/40; A61L27/44; A61L27/46; A61L27/50; A61L27/56; C04B35/00; C04B35/01; C04B35/447; A61F2002/30001; A61F2002/30003; A61F2002/30004; A61F2002/30011; A61F2002/3092; A61F2/3094; A61F2002/30968; A61F2250/00; A61F2250/0014; A61F2250/0023; A61F2310/00; A61F2310/00005; A61F2310/00179; A61F2310/00293; C04B2111/00; C04B2111/00474; C04B2111/00836

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 54 words
A sintered microporous hydroxyapatite material in a granular form composed of granules each having a diameter in the range from 0.1 to 2.0 mm and an open pore structure of micropores with a pore diameter distribution in the range from 0.01 to 0.10 mm and a porosity in the range from 20 to 50%.
Claim 2
Dependent Claim 54 words
A sintered microporous hydroxyapatite material in a granular form composed of granules each having a diameter in the range from 0.1 to 2.0 mm and an open pore structure of micropores with a pore diameter distribution in the range from 0.01 to 0.10 mm and a porosity in the range from 20 to 50%.
Claim 3
Dependent Claim 22 words
The sintered microporous hydroxyapatite material in a granular form as claimed in claim 1 which is slurried with a physiological saline solution.
Claim 4
Dependent Claim 40 words
The sintered microporous hydroxyapatite material in a granular form as claimed in claim 2 wherein the amount of the saline solution is in the range from 50 to 200% of the granules of the sintered porous hydroxyapatite material by weight.
Claim 5
Dependent Claim 49 words
A sintered porous hydroxyapatite material in the form of a bone substitute member having an open pore structure provided with micropores having a pore diameter distribution in the range from 0.01 to 0.10 mm and pores having a pore diameter distribution in the range from 0.2 to 2.0 mm.
Claim 6
Dependent Claim 49 words
A sintered porous hydroxyapatite material in the form of a bone substitute member having an open pore structure provided with micropores having a pore diameter distribution in the range from 0.01 to 0.10 mm and pores having a pore diameter distribution in the range from 0.2 to 2.0 mm.
Claim 7
Dependent Claim 32 words
The sintered porous hydroxyapatite material in the form of a bone substitute member as claimed in claim 4 wherein the porosity of the material is in the range from 30 to 40%.
Claim 8
Dependent Claim 83 words
A sintered porous hydroxyapatite material in the form of a bone substitute member having a core-and-crust structure with an open pore structure which comprises a core partion provided with micropores having a pore diameter distribution in the range from 0.01 to 0.10 mm and pores having a pore diameter distribution in the range from 0.2 to 2.0 mm and a crust layer formed on the core portion provided with micropores having a pore diameter distribution in the range from 0.01 to 0.10 mm.
Claim 9
Dependent Claim 83 words
A sintered porous hydroxyapatite material in the form of a bone substitute member having a core-and-crust structure with an open pore structure which comprises a core partion provided with micropores having a pore diameter distribution in the range from 0.01 to 0.10 mm and pores having a pore diameter distribution in the range from 0.2 to 2.0 mm and a crust layer formed on the core portion provided with micropores having a pore diameter distribution in the range from 0.01 to 0.10 mm.
Claim 10
Dependent Claim 33 words
The sintered porous hydroxyapatite material in the form of a bone substitute member as claimed in claim 6 wherein the crust layer has a thickness in the range from 0.1 to 2.0 mm.

References Cited (Backward Citations)

US3423829A Cited
US3919139A Cited
US3913229A Cited
US4222128A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1989-12-15 1990-06-16 1990-12-16 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1993-12-15 1994-06-16 1994-12-16 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1997-12-15 1998-06-16 1998-12-16 $7700.00 Window Closed / Lapsed

Assigned Categories & Tags

No categories assigned to this patent yet.

Assign Category Tag