Patent US6262247B1 successfully refreshed from Google Patents.
US6262247B1
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Polycyclic aromatic hydrocarbon induced molecules
Assignee: Incyte Corp
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Filing: 1999-08-30
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Granted: 2001-07-17
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Expires: 2019-08-30
Abstract
Abstract The invention provides novel nucleic acid molecules and encoded proteins associated with response to polycyclic aromatic hydrocarbon exposure. The invention also provides expression vectors, host cells, and antibodies. The invention also provides methods for screening or purifying ligands and diagnosing, treating or preventing disorders associated with polycyclic aromatic hydrocarbon exposure.
Inventors
- 👤 Matthew R. Kaser
- 👤 Yalda Azimzai
- 👤 Henry Yue
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 22:36
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/46; C07K14/47; A; A61; A61P; A61P35/00; C12; C12Q; C12Q1/00; C12Q1/68; C12Q1/6876; C12Q1/6883; A61K; A61K38/00; C12Q2600/00; C12Q2600/142; C12Q2600/158
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
90 words
A substantially purified nucleic acid molecule expressed in response to polycyclic aromatic hydrocarbon exposure comprising: (a) a nucleic acid molecule encoding a protein selected from SEQ ID NOs:7, 8 and 14; (b) a nucleic acid molecule selected from the group consisting of SEQ ID NOs:1-5 and 9-13; or (c) a nucleic acid molecule which is the complement of the nucleic acid molecule of (a) or (b) wherein each and every nucleotide of the complement is complementary to each and every nucleotide of the nucleic acid molecule of (a) or (b).
Claim 2
Dependent Claim
90 words
A substantially purified nucleic acid molecule expressed in response to polycyclic aromatic hydrocarbon exposure comprising: (a) a nucleic acid molecule encoding a protein selected from SEQ ID NOs:7, 8 and 14; (b) a nucleic acid molecule selected from the group consisting of SEQ ID NOs:1-5 and 9-13; or (c) a nucleic acid molecule which is the complement of the nucleic acid molecule of (a) or (b) wherein each and every nucleotide of the complement is complementary to each and every nucleotide of the nucleic acid molecule of (a) or (b).
Claim 3
Dependent Claim
13 words
A composition comprising at least one nucleic acid molecule of claim 1 .
Claim 4
Dependent Claim
12 words
An expression vector comprising the nucleic acid molecule of claim 1 .
Claim 5
Dependent Claim
11 words
A host cell comprising the expression vector of claim 3 .
Claim 6
Dependent Claim
32 words
A method for producing a protein, the method comprising: (a) culturing the host cell of claim 4 under conditions for expression of the protein; and (b) recovering the protein from cell culture.
Claim 7
Dependent Claim
64 words
A substantially purified nucleic acid molecule expressed in response to polycyclic aromatic hydrocarbon exposure comprising: (a) a nucleic acid molecule encoding a protein of SEQ ID NOS:6; or (b) a nucleic acid molecule which is the complement of the nucleic acid molecule of (a) wherein each every nucleotide of the complement is complementary to each every nucleotide of the nucleic acid molecule of (a).
Claim 8
Dependent Claim
64 words
A substantially purified nucleic acid molecule expressed in response to polycyclic aromatic hydrocarbon exposure comprising: (a) a nucleic acid molecule encoding a protein of SEQ ID NOS:6; or (b) a nucleic acid molecule which is the complement of the nucleic acid molecule of (a) wherein each every nucleotide of the complement is complementary to each every nucleotide of the nucleic acid molecule of (a).
Claim 9
Dependent Claim
11 words
A composition comprising the nucleic acid molecule of claim 6 .
References Cited (Backward Citations)
WO1999006439A2
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2004-07-16 | 2005-01-15 | 2005-07-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2008-07-16 | 2009-01-15 | 2009-07-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2012-07-16 | 2013-01-15 | 2013-07-17 | $7700.00 | Window Closed / Lapsed |