Patent US4476862A successfully refreshed from Google Patents.
US6200310B1
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US
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Monitoring of myocardial revascularization
Assignee: Biosense Webster Inc
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Filing: 1997-09-15
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Granted: 2001-03-13
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Expires: 2017-09-15
Abstract
Abstract Apparatus for PNR treatment, including an elongate probe having a distal end for engaging heart tissue of a subject, and a revascularization device, which imparts energy to the heart tissue for generating perfusion-enhancing channels therein. A sensor provides an indication responsive to the treatment, preferably by receiving signals generated by the body of the subject.
Inventors
- 👤 Shlomo Ben-Haim
- 👤 Uri Yaron
- 👤 Joel Zilberstein
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 00:24
CPC Classifications
A; A61; A61N; A61N5/00; A61N5/06; A61N5/0601; A61B; A61B18/00; A61B18/18; A61B18/20; A61B18/22; A61B18/24; A61B17/00; A61B17/00234; A61B2017/00238; A61B2017/00243; A61B2017/00247; A61B2018/00315; A61B2018/00345; A61B2018/00351; A61B2018/00392; A61B2018/2255; A61B2018/2272; A61B5/00; A61B5/0059; A61B5/0071; A61B5/0082; A61B5/0084; A61B5/06; A61B8/00; A61B8/12; A61B8/44; A61B8/4483; A61B8/4488
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
61 words
Apparatus for PMR treatment, comprising: an elongate probe having a distal end for engaging heart tissue of a subject, and comprising a revascularization device, which imparts energy to the heart tissue for generating perfusion-enhancing channels therein; and a sensor, which provides an indication responsive to the treatment wherein the sensor comprises a blood flow sensor, which generate signals responsive to microcirculation.
Claim 2
Dependent Claim
61 words
Apparatus for PMR treatment, comprising: an elongate probe having a distal end for engaging heart tissue of a subject, and comprising a revascularization device, which imparts energy to the heart tissue for generating perfusion-enhancing channels therein; and a sensor, which provides an indication responsive to the treatment wherein the sensor comprises a blood flow sensor, which generate signals responsive to microcirculation.
Claim 3
Dependent Claim
22 words
Apparatus according to claim 1 , wherein the sensor receives signals generated by the body of the subject responsive to the treatment.
Claim 4
Dependent Claim
78 words
Apparatus for PMR treatment, comprising: an elongate probe having a distal end for engaging heart tissue of a subject, and comprising a revascularization device, which imparts energy to the heart tissue for generating perfusion-enhancing channels therein; a sensor, which provides an indication responsive to the treatment; and signal processing circuitry, which is coupled to the sensor and analyzes the signals to provide an indication of the efficacy of the treatment, wherein the circuitry detects an elevated ST segment.
Claim 5
Dependent Claim
78 words
Apparatus for PMR treatment, comprising: an elongate probe having a distal end for engaging heart tissue of a subject, and comprising a revascularization device, which imparts energy to the heart tissue for generating perfusion-enhancing channels therein; a sensor, which provides an indication responsive to the treatment; and signal processing circuitry, which is coupled to the sensor and analyzes the signals to provide an indication of the efficacy of the treatment, wherein the circuitry detects an elevated ST segment.
Claim 6
Dependent Claim
12 words
Apparatus according to claim 3 , wherein the sensor comprises an electrode.
Claim 7
Dependent Claim
19 words
Apparatus according to claim 4 , wherein the electrode is positioned on the probe adjacent the distal end thereof.
Claim 8
Dependent Claim
13 words
Apparatus according to claim 3 , wherein the sensor comprises an optical sensor.
Claim 9
Dependent Claim
32 words
Apparatus according to claim 6 , and comprising a waveguide, which transmits fluorescence-stimulating radiation to the myocardial tissue, wherein the sensor receives fluorescence emitted from the tissue and generates signals responsive thereto.
Claim 10
Dependent Claim
17 words
Apparatus according to claim 3 , wherein the revascularization device applies laser radiation to the heart tissue.
Claim 11
Dependent Claim
17 words
Apparatus according to claim 3 , wherein the revascularization device applies RF energy to the heart tissue.
Claim 12
Dependent Claim
18 words
Apparatus according to claim 3 , wherein the revascularization device applies high-intensity ultrasonic radiation to the heart tissue.
Claim 13
Dependent Claim
17 words
Apparatus according to claim 3 , wherein the revascularization device applies mechanical energy to the heart tissue.
Claim 14
Independent Claim
96 words
A method for monitored PMR treatment of the heart of a subject, comprising: bringing a probe, including a revascularization device for imparting energy to the heart, into engagement with heart tissue of a subject; imparting energy to the heart tissue using the device so as to generate perfusion-enhancing channels therein; transmitting fluorescence-stimulating radiation to the heart tissue through an optical waveguide; and receiving a signal from the body of the subject responsive to the treatment by receiving energy reflected from the heart tissue by receiving fluorescence radiation emitted from the heart tissue through a light detector.
Claim 15
Independent Claim
96 words
A method for monitored PMR treatment of the heart of a subject, comprising: bringing a probe, including a revascularization device for imparting energy to the heart, into engagement with heart tissue of a subject; imparting energy to the heart tissue using the device so as to generate perfusion-enhancing channels therein; transmitting fluorescence-stimulating radiation to the heart tissue through an optical waveguide; and receiving a signal from the body of the subject responsive to the treatment by receiving energy reflected from the heart tissue by receiving fluorescence radiation emitted from the heart tissue through a light detector.
Claim 16
Dependent Claim
15 words
A method according to claim 12 , wherein receiving fluorescence radiation comprises receiving autofluorescent radiation.
Claim 17
Dependent Claim
24 words
A method according to claim 12 , wherein receiving fluorescence radiation comprises receiving fluorescent radiation from an agent administered into the subject's blood stream.
Claim 18
Independent Claim
83 words
A method for monitored PMR treatment of the heart of a subject, comprising: bringing a probe, including a revascularization device for imparting energy to the heart, into engagement with heart tissue of a subject; imparting energy to the heart tissue using the device so as to generate perfusion-enhancing channels therein; receiving a signal from the body of the subject responsive to the treatment; and processing the signal to provide an indication of the efficacy of the treatment by detecting an elevated ST segment.
Claim 19
Independent Claim
83 words
A method for monitored PMR treatment of the heart of a subject, comprising: bringing a probe, including a revascularization device for imparting energy to the heart, into engagement with heart tissue of a subject; imparting energy to the heart tissue using the device so as to generate perfusion-enhancing channels therein; receiving a signal from the body of the subject responsive to the treatment; and processing the signal to provide an indication of the efficacy of the treatment by detecting an elevated ST segment.
Claim 20
Dependent Claim
17 words
A method according to claim 15 , wherein imparting energy to the heart comprises imparting laser radiation.
Claim 21
Dependent Claim
17 words
A method according to claim 15 , wherein imparting energy to the heart comprises imparting RF radiation.
Claim 22
Dependent Claim
18 words
A method according to claim 15 , wherein imparting energy to the heart comprises imparting high-intensity ultrasonic radiation.
Claim 23
Dependent Claim
17 words
A method according to claim 15 , wherein imparting energy to the heart comprises imparting mechanical energy.
Claim 24
Dependent Claim
89 words
Apparatus for PMR treatment, comprising: an elongate probe having a distal end for engaging heart tissue of a subject, and comprising a revascularization device, which imparts energy to the heart tissue for generating perfusion-enhancing channels therein; a sensor, which provides an indication responsive to the treatment; and signal processing circuitry, which is coupled to the sensor and analyzes the signals to provide an indication of the efficacy of the treatment, wherein the circuitry detects an arrhythmia, and wherein the arrhythmia detected by the circuitry comprises at least one VPB.
Claim 25
Dependent Claim
89 words
Apparatus for PMR treatment, comprising: an elongate probe having a distal end for engaging heart tissue of a subject, and comprising a revascularization device, which imparts energy to the heart tissue for generating perfusion-enhancing channels therein; a sensor, which provides an indication responsive to the treatment; and signal processing circuitry, which is coupled to the sensor and analyzes the signals to provide an indication of the efficacy of the treatment, wherein the circuitry detects an arrhythmia, and wherein the arrhythmia detected by the circuitry comprises at least one VPB.
Claim 26
Independent Claim
81 words
A method for monitored PMR treatment of the heart of a subject, comprising: bringing a probe, including a revascularization device for imparting energy to the heart, into engagement with heart tissue of a subject; imparting energy to the heart tissue using the device so as to generate perfusion-enhancing channels therein; and receiving a signal from the body of the subject responsive to the treatment by receiving signals responsive to microcirculation blood flow rate adjacent a designated channel location within the heart.
Claim 27
Independent Claim
81 words
A method for monitored PMR treatment of the heart of a subject, comprising: bringing a probe, including a revascularization device for imparting energy to the heart, into engagement with heart tissue of a subject; imparting energy to the heart tissue using the device so as to generate perfusion-enhancing channels therein; and receiving a signal from the body of the subject responsive to the treatment by receiving signals responsive to microcirculation blood flow rate adjacent a designated channel location within the heart.
Claim 28
Independent Claim
85 words
A method for monitored PMR treatment of the heart of a subject, comprising: bringing a probe, including a revascularization device for imparting energy to the heart, into engagement with heart tissue of a subject; imparting energy to the heart tissue using the device so as to generate perfusion-enhancing channels therein; receiving a signal from the body of the subject responsive to the treatment; and processing the signal to provide an indication of the efficacy of the treatment by detecting an arrhythmia through detecting a VPB.
Claim 29
Independent Claim
85 words
A method for monitored PMR treatment of the heart of a subject, comprising: bringing a probe, including a revascularization device for imparting energy to the heart, into engagement with heart tissue of a subject; imparting energy to the heart tissue using the device so as to generate perfusion-enhancing channels therein; receiving a signal from the body of the subject responsive to the treatment; and processing the signal to provide an indication of the efficacy of the treatment by detecting an arrhythmia through detecting a VPB.
References Cited (Backward Citations)
US4788975A
Cited
US4788975B1
Cited
US5125924A
Cited
US5125926A
Cited
US5380316A
Cited
US5389096A
Cited
US5554152A
Cited
WO1994006349A1
Cited
US5450846A
Cited
US5433198A
Cited
US5350375A
Cited
US5403356A
Cited
US5391199A
Cited
US5431168A
Cited
WO1995007657A1
Cited
US5651786A
Cited
US5487391A
Cited
US5566673A
Cited
WO1996005768A1
Cited
US6023638A
Cited
US5824005A
Cited
WO1997024983A2
Cited
WO1997025101A2
Cited
WO1997029803A1
Cited
US5769843A
Cited
US5891133A
Cited
US5871495A
Cited
US5893848A
Cited
US5724975A
Cited
US5964757A
Cited
US6024739A
Cited
US6027473A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2004-03-12 | 2004-09-11 | 2005-03-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2008-03-12 | 2008-09-11 | 2009-03-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2012-03-12 | 2012-09-11 | 2013-03-13 | $7700.00 | Window Closed / Lapsed |