Patent US6180351B1 successfully refreshed from Google Patents.
US6180351B1
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Chemical array fabrication with identifier
Assignee: Agilent Technologies Inc
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Filing: 1999-07-22
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Granted: 2001-01-30
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Expires: 2019-07-22
Abstract
Abstract A method of generating an addressable array of biopolymers, such as DNA probes, on a substrate. The method includes receiving from a remote station, information on a layout of the array and an associated first identifier. A local identifier is generated corresponding to the first identifier and associated array, the local identifier being shorter in length than the corresponding first identifier. The addressable array is fabricated on the substrate in accordance with the received layout information. A first copy of the local identifier is applied to the substrate or a housing carrying the substrate. The fabricated array and the first copy of the local identifier are shipped to a remote user station. A method at the corresponding user station, and apparatus and computer program products useful at either station, are further provided.
Inventors
- 👤 Herbert F. Cattell
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 12:14
CPC Classifications
C; C40; C40B; C40B50/00; C40B50/14; C40B50/16; C40B40/00; C40B40/04; C12; C12Q; C12Q1/00; C12Q1/68; C12Q1/6813; C12Q1/6834; C12Q1/6837
Claims Analysis
Total Claims: 25
Claim 1
Independent Claim
135 words
A method of generating an addressable array of biopolymers on a substrate, comprising: (a) receiving from a remote station, information on a layout of the array and an associated first identifier; (b) generating a local identifier corresponding to the first identifier and associated array layout information, the local identifier being shorter in length than the corresponding first identifier; (c) fabricating the addressable array on the substrate in accordance with the received layout information; (d) applying a first copy of the local identifier to the substrate or a housing carrying the substrate; (d) shipping the fabricated array and the first copy of the local identifier to a remote station; and (e) forwarding a second copy of the corresponding local identifier to the remote station such that the local identifier is associated with the corresponding first identifier.
Claim 2
Independent Claim
135 words
A method of generating an addressable array of biopolymers on a substrate, comprising: (a) receiving from a remote station, information on a layout of the array and an associated first identifier; (b) generating a local identifier corresponding to the first identifier and associated array layout information, the local identifier being shorter in length than the corresponding first identifier; (c) fabricating the addressable array on the substrate in accordance with the received layout information; (d) applying a first copy of the local identifier to the substrate or a housing carrying the substrate; (d) shipping the fabricated array and the first copy of the local identifier to a remote station; and (e) forwarding a second copy of the corresponding local identifier to the remote station such that the local identifier is associated with the corresponding first identifier.
Claim 3
Dependent Claim
12 words
A method according to claim 1 wherein the first identifier is unique.
Claim 4
Dependent Claim
11 words
A method according to claim 1 wherein the biopolymers are polynucleotides.
Claim 5
Dependent Claim
11 words
A method according to claim 1 wherein the biopolymers are DNA.
Claim 6
Dependent Claim
27 words
A method according to claim 1 wherein the second copy of the local identifier is forwarded to the remote station in association with the corresponding first identifier.
Claim 7
Dependent Claim
28 words
A method according to claim 5 wherein the second copy of the local identifier is applied to a same medium to which the corresponding first identifier is applied.
Claim 8
Dependent Claim
35 words
A method according to claim 1 wherein the second copy of the local identifier is shipped to the remote station on or in the same package with the corresponding first identifier and the fabricated array.
Claim 9
Dependent Claim
27 words
A method according to claim 7 wherein the second copy of the local identifier and first identifier are present together on a packaging containing the fabricated array.
Claim 10
Dependent Claim
20 words
A method according to claim 1 wherein a second copy of the local identifier is communicated to the remote station.
Claim 11
Dependent Claim
37 words
A method according to claim 1 wherein the array and the first copy of the corresponding local identifier are shipped to the same remote station from which the corresponding first identifier and the layout information were received.
Claim 12
Dependent Claim
39 words
A method according to claim 1 wherein the array and the first copy of the corresponding local identifier are shipped to a remote station different from that from which the corresponding first identifier and the layout information were received.
Claim 13
Dependent Claim
25 words
A method according to claim 1 , additionally comprising saving the received first identifiers in a memory each in association with the corresponding local identifier.
Claim 14
Dependent Claim
25 words
A method according to claim 12 additionally comprising saving array layout information for each array in a memory, in association with the corresponding local identifier.
Claim 15
Independent Claim
165 words
A method of generating, at a central fabrication station, addressable arrays of biopolymers on multiple substrates, comprising: (a) receiving from each of multiple remote stations, information on a layout of an array and an associated first identifier; (b) for each received first identifier and associated array, generating a local identifier corresponding to the first identifier and associated array, the local identifier being shorter in length than the corresponding first identifier; (c) fabricating an addressable array on the substrate in accordance with each received layout information; (d) applying a first copy of each local identifier to the substrate or a housing carrying the substrate, which substrate carries the array corresponding to the generated local identifier; (d) shipping each of the fabricated arrays and the first copy of the corresponding local identifier to one or more of the remote stations; and (e) forwarding a second copy of each corresponding local identifier to a remote station such that the local identifier is associated with the corresponding first identifier.
Claim 16
Independent Claim
165 words
A method of generating, at a central fabrication station, addressable arrays of biopolymers on multiple substrates, comprising: (a) receiving from each of multiple remote stations, information on a layout of an array and an associated first identifier; (b) for each received first identifier and associated array, generating a local identifier corresponding to the first identifier and associated array, the local identifier being shorter in length than the corresponding first identifier; (c) fabricating an addressable array on the substrate in accordance with each received layout information; (d) applying a first copy of each local identifier to the substrate or a housing carrying the substrate, which substrate carries the array corresponding to the generated local identifier; (d) shipping each of the fabricated arrays and the first copy of the corresponding local identifier to one or more of the remote stations; and (e) forwarding a second copy of each corresponding local identifier to a remote station such that the local identifier is associated with the corresponding first identifier.
Claim 17
Dependent Claim
12 words
A method according to claim 14 wherein the first identifier is unique.
Claim 18
Dependent Claim
44 words
A method according to claim 14 additionally comprising applying a second copy of each local identifier and corresponding first identifier to a same medium, and shipping the medium and corresponding array to the same remote station from which the corresponding first identifier was received.
Claim 19
Dependent Claim
28 words
A method according to claim 14 wherein a second copy of each local identifier is communicated to the remote station from which the corresponding first identifier was received.
Claim 20
Dependent Claim
29 words
A method according to claim 14 , additionally comprising at the central fabrication station, saving received first identifiers in a memory each in association with the corresponding local identifiers.
Claim 21
Dependent Claim
27 words
A method according to claim 18 additionally comprising saving array layout information for each array in a memory in association with the corresponding local and first identifiers.
Claim 22
Dependent Claim
148 words
A computer program product, comprising: a computer readable storage medium having a computer program stored thereon for performing, when loaded into a computer communicating with a fabricator to fabricate an addressable array on the substrate, the steps of: (a) receiving from a remote station, information on a layout of the array and an associated first identifier; (b) generating a local identifier corresponding to the first identifier and associated array, the local identifier being shorter in length than the corresponding first identifier; (c) controlling fabrication of the addressable array on the substrate in accordance with the received layout information; (d) applying a first copy of the local identifier to the substrate or a housing carrying the substrate; and (e) generating a second copy of the corresponding local identifier and forwarding the second copy to the remote station such that the local identifier is associated with the corresponding first identifier.
Claim 23
Dependent Claim
148 words
A computer program product, comprising: a computer readable storage medium having a computer program stored thereon for performing, when loaded into a computer communicating with a fabricator to fabricate an addressable array on the substrate, the steps of: (a) receiving from a remote station, information on a layout of the array and an associated first identifier; (b) generating a local identifier corresponding to the first identifier and associated array, the local identifier being shorter in length than the corresponding first identifier; (c) controlling fabrication of the addressable array on the substrate in accordance with the received layout information; (d) applying a first copy of the local identifier to the substrate or a housing carrying the substrate; and (e) generating a second copy of the corresponding local identifier and forwarding the second copy to the remote station such that the local identifier is associated with the corresponding first identifier.
Claim 24
Dependent Claim
24 words
A computer program product according to claim 20 wherein the second copy is forwarded to the remote station by communication to the remote station.
Claim 25
Dependent Claim
31 words
A computer program product according to claim 20 wherein the second copy is forwarded by writing to a same medium as the corresponding first identifier for shipping to the remote station.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2004-01-30 | 2004-07-31 | 2005-01-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2008-01-30 | 2008-07-31 | 2009-01-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2012-01-30 | 2012-07-31 | 2013-01-30 | $7700.00 | Window Closed / Lapsed |