US6168619B1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Intravascular stent having a coaxial polymer member and end sleeves
Assignee: Boston Scientific Scimed Inc
•
Filing: 1998-10-16
•
Granted: 2001-01-02
•
Expires: 2018-10-16
Abstract
Abstract A radially-expandable stent for insertion into a lumen is described. The stent is composed of a radially-expandable support stent and a polymer tubular member co-axially disposed over the support stent. Tubular end sleeves are disposed around the first and second ends of the polymer-surrounded support stent to secure the tubular member and to provide other improvements.
Inventors
- 👤 Linh Dinh
- 👤 Beren Correa
- 👤 Paul Cherkas
- 👤 Angelica Alvarado
- 👤 Irina D. Pomerantseva
- 👤 Sudha Thakur
- 👤 Robert Eury
- 👤 Michael Froix
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 10:46
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61F2/07; A61F2/82; A61F2/852; A61F2/86; A61F2/89; A61F2/90; A61F2/91; A61F2002/075; A61F2220/00; A61F2220/0025; A61F2220/0075; A61F2250/00; A61F2250/0058; A61F2250/006; A61F2250/0063
Claims Analysis
Total Claims: 81
Claim 1
Independent Claim
138 words
A radially-expandable stent for insertion into a lumen, comprising a radially expandable support stent of a selected axial length having first and second ends; a polymer tubular member co-axially disposed over the support stent and extending the length of the support stent, the polymer member being radially expandable with the support stent to an expanded diameter and having an internal surface and an external surface, and tubular end sleeves having an internal surface and an external surface, said end sleeves being disposed around said first and second ends of the polymer-surrounded support stent with the end sleeves' internal surfaces in contact with the polymer tubular member and the end sleeves' external surfaces exposed, said end sleeves (i) being radially expandable with the support stent to an expanded diameter, and (ii) covering 50% or less of the stent length.
Claim 2
Dependent Claim
138 words
A radially-expandable stent for insertion into a lumen, comprising a radially expandable support stent of a selected axial length having first and second ends; a polymer tubular member co-axially disposed over the support stent and extending the length of the support stent, the polymer member being radially expandable with the support stent to an expanded diameter and having an internal surface and an external surface, and tubular end sleeves having an internal surface and an external surface, said end sleeves being disposed around said first and second ends of the polymer-surrounded support stent with the end sleeves' internal surfaces in contact with the polymer tubular member and the end sleeves' external surfaces exposed, said end sleeves (i) being radially expandable with the support stent to an expanded diameter, and (ii) covering 50% or less of the stent length.
Claim 3
Dependent Claim
16 words
The stent of claim 1 , wherein the support stent is composed of a biocompatible metal.
Claim 4
Dependent Claim
30 words
The stent of claim 2 , wherein the metal is selected from the group consisting of stainless steel, titanium, tungsten, tantalum, gold, platinum, cobalt, iridium and alloys of these materials.
Claim 5
Dependent Claim
13 words
The stent of claim 2 , wherein the metal is a shape-memory alloy.
Claim 6
Dependent Claim
15 words
The stent of claim 1 , wherein the support stent is composed of a polymer.
Claim 7
Dependent Claim
13 words
The stent of claim 5 , wherein the polymer is a memory polymer.
Claim 8
Dependent Claim
15 words
The stent of claim 6 , wherein the memory polymer is formed of a copolymer.
Claim 9
Dependent Claim
43 words
The stent of claim 1 , wherein the polymer tubular member is formed into a cylindrical shape and secured in the cylindrical shape by joining overlapping edges of the member by a mechanical means selected from ultrasonic welding, resistive heating and laser irradiation.
Claim 10
Dependent Claim
25 words
The stent of claim 1 , wherein the polymer tubular member is secured to the support stent in an unexpanded diameter by a biocompatible adhesive.
Claim 11
Dependent Claim
15 words
The stent of claim 9 , wherein the biocompatible adhesive is a fluorinated thermoplastic polymer.
Claim 12
Dependent Claim
29 words
The stent of claim 10 , wherein the fluorinated thermoplastic is selected from the group consisting of fluorinated ethylene/propylene copolymers, perfluoroalkoxy fluorocarbons, ethylene/tetrafluoroethylene copolymers, fluoroacrylates, and fluorinated polyvinyl ethers.
Claim 13
Dependent Claim
29 words
The stent of claim 1 , wherein the polymer member is composed of a polymer selected from the group consisting of polyamides, polyimides, silicones, acrylates, methacrylates and fluorinated polyolefins.
Claim 14
Dependent Claim
14 words
The stent of claim 1 , wherein the polymer member is composed of polytetrafluoroethylene.
Claim 15
Dependent Claim
17 words
The stent of claim 13 , wherein the polytetrafluoroethylene tubular member is composed of biaxially oriented polytetrafluoroethylene.
Claim 16
Dependent Claim
17 words
The stent of claim 13 , wherein the polytetrafluoroethylene tubular member is composed of uniaxially oriented polytetrafluoroethylene.
Claim 17
Dependent Claim
31 words
The stent of claim 13 , wherein the polytetrafluoroethylene tubular member has a porosity of at least about 5% and the member further includes a therapeutic agent incorporated into the pores.
Claim 18
Dependent Claim
15 words
The stent of claim 1 , wherein the polymer member further includes a therapeutic agent.
Claim 19
Dependent Claim
20 words
The stent of claim 17 , wherein the therapeutic agent is an agent effective to inhibit smooth muscle cell proliferation.
Claim 20
Dependent Claim
22 words
The stent of claim 17 , wherein the therapeutic agent is an agent effective to inhibit proliferation or migration of fibroblast cells.
Claim 21
Dependent Claim
25 words
The stent of claim 17 , wherein the therapeutic agent is selected from the group consisting of anticoagulants, antiplatlet agents, thrombolytic agents and antibacterial agents.
Claim 22
Dependent Claim
23 words
The stent of claim 20 , wherein the thrombolytic agent is selected from the group consisting of urokinase, streptokinase and tissue plasminogen activator.
Claim 23
Dependent Claim
16 words
The stent of claim 17 , wherein the agent is paclitaxel or a derivative of paclitaxel.
Claim 24
Dependent Claim
42 words
The stent of claim 17 , wherein the therapeutic agent is selected from the group consisting of colchicine, heparin, warfarin, low molecular weight heparin, hirudin, glucocorticoids, angiotensin converting enzyme inhibitors, vincristine, actinomycin, platelet derived growth factor, vascular endothelial growth factor and oligonucleotides.
Claim 25
Dependent Claim
14 words
The stent of claim 17 , wherein the therapeutic agent is a topoisomerase inhibitor.
Claim 26
Dependent Claim
17 words
The stent of claim 24 , wherein the topoisomerase inhibitor is camptothecin or an analogue of camptothecin.
Claim 27
Dependent Claim
15 words
The stent of claim 17 , wherein the polymer member includes a second therapeutic agent.
Claim 28
Dependent Claim
28 words
The stent of claim 26 , wherein the therapeutic agent is paclitaxel and the second therapeutic agent is selected from the group consisting of camptothecin, colchicine and dexamethasone.
Claim 29
Dependent Claim
16 words
The stent of claim 1 , wherein the end sleeves are composed of a biocompatible metal.
Claim 30
Dependent Claim
30 words
The stent of claim 28 , wherein the metal is selected from the group consisting of stainless steel, titanium, tungsten, tantalum, gold, platinum, cobalt, iridium and alloys of these materials.
Claim 31
Dependent Claim
13 words
The stent of claim 28 , wherein the metal is a shape-memory alloy.
Claim 32
Dependent Claim
13 words
The stent of claim 28 , wherein the metal is coated with polytetrafluoroethylene.
Claim 33
Dependent Claim
15 words
The stent of claim 1 , wherein the end sleeves are composed of a polymer.
Claim 34
Dependent Claim
16 words
The stent of claim 1 , wherein the end sleeves are composed of an elastic polymer.
Claim 35
Dependent Claim
15 words
The stent of claim 1 , wherein the end sleeves are composed of a copolymer.
Claim 36
Dependent Claim
13 words
The stent of claim 32 , wherein the polymer is a memory polymer.
Claim 37
Dependent Claim
15 words
The stent of claim 35 , wherein the memory polymer is formed of a copolymer.
Claim 38
Dependent Claim
24 words
The stent of claim 1 , wherein the end sleeves are secured on the ends of the polymer-covered support stent by a mechanical means.
Claim 39
Dependent Claim
24 words
The stent of claim 1 , wherein the end sleeves are secured on the ends of the polymer-covered support stent by a biocompatible adhesive.
Claim 40
Dependent Claim
98 words
An improvement in a stent of a selected axial length and having a polymer tubular member coaxially disposed about the stent, said improvement comprising tubular end sleeves, each end sleeve having an internal surface and an external surface, said end sleeves being disposed around each end of the stent such that the internal surface of each end sleeve is in contact with the polymer tubular member and the external surface of each end sleeve is exposed, said end sleeves being radially expandable with the stent to an expanded diameter and covering 50% or less of the stent length.
Claim 41
Dependent Claim
98 words
An improvement in a stent of a selected axial length and having a polymer tubular member coaxially disposed about the stent, said improvement comprising tubular end sleeves, each end sleeve having an internal surface and an external surface, said end sleeves being disposed around each end of the stent such that the internal surface of each end sleeve is in contact with the polymer tubular member and the external surface of each end sleeve is exposed, said end sleeves being radially expandable with the stent to an expanded diameter and covering 50% or less of the stent length.
Claim 42
Independent Claim
119 words
A method of preparing a stent for insertion into a lumen, comprising providing a radially expandable support stent of a selected axial length and having first and second ends; placing a polymer tubular member co-axially over the support stent and extending the length of the stent, the polymer member being radially expandable with the support stent to an expanded diameter, and securing tubular end sleeves around the first and second ends of the polymer-surrounded support stent, said end sleeves each having an internal surface in contact with the polymer tubular member and an external surface exposed, said end sleeves being radially expandable with the support stent to an expanded diameter and covering 50% or less of the stent length.
Claim 43
Independent Claim
119 words
A method of preparing a stent for insertion into a lumen, comprising providing a radially expandable support stent of a selected axial length and having first and second ends; placing a polymer tubular member co-axially over the support stent and extending the length of the stent, the polymer member being radially expandable with the support stent to an expanded diameter, and securing tubular end sleeves around the first and second ends of the polymer-surrounded support stent, said end sleeves each having an internal surface in contact with the polymer tubular member and an external surface exposed, said end sleeves being radially expandable with the support stent to an expanded diameter and covering 50% or less of the stent length.
Claim 44
Dependent Claim
19 words
The method of claim 40 , wherein said providing includes providing a support stent composed of a biocompatible metal.
Claim 45
Dependent Claim
30 words
The method of claim 41 , wherein the metal is selected from the group consisting of stainless steel, titanium, tungsten, tantalum, gold, platinum, cobalt, iridium and alloys of these materials.
Claim 46
Dependent Claim
13 words
The method of claim 41 , wherein the metal is a shape-memory alloy.
Claim 47
Dependent Claim
18 words
The method of claim 40 , wherein said providing includes providing a support stent composed of a polymer.
Claim 48
Dependent Claim
13 words
The method of claim 44 , wherein the polymer is a memory polymer.
Claim 49
Dependent Claim
15 words
The method of claim 45 , wherein the memory polymer is formed of a copolymer.
Claim 50
Dependent Claim
43 words
The method of claim 40 , wherein the polymer tubular member is formed into a cylindrical shape and secured in the cylindrical shape by joining overlapping edges of the member by a mechanical means selected from ultrasonic welding, resistive heating and laser irradiation.
Claim 51
Dependent Claim
32 words
The method of claim 40 , wherein said placing of the polymer tubular member includes securing the member to the support stent in an unexpanded diameter by means of a biocompatible adhesive.
Claim 52
Dependent Claim
15 words
The method of claim 48 , wherein the biocompatible adhesive is a fluorinated thermoplastic polymer.
Claim 53
Dependent Claim
29 words
The method of claim 49 , wherein the fluorinated thermoplastic is selected from the group consisting of fluorinated ethylene/propylene copolymers, perfluoroalkoxy fluorocarbons, ethylene/tetrafluoroethylene copolymers, fluoroacrylates, and fluorinated polyvinyl ethers.
Claim 54
Dependent Claim
32 words
The method of claim 40 , wherein said placing includes placing a polymer member composed of a polymer selected from the group consisting of polyamides, polyimides, silicones, acrylates, methacrylates and fluorinated polyolefins.
Claim 55
Dependent Claim
20 words
The method of claim 40 , wherein said placing includes placing a polytetrafluoroethylene tubular member composed of biaxially oriented polytetrafluoroethylene.
Claim 56
Dependent Claim
18 words
The method of claim 40 , wherein said placing includes placing a polytetrafluoroethylene composed of uniaxially oriented polytetrafluoroethylene.
Claim 57
Dependent Claim
32 words
The method of claim 40 , wherein said placing includes placing a polytetrafluoroethylene tubular member having a porosity of at least about 5% and having a therapeutic agent incorporated into the pores.
Claim 58
Dependent Claim
18 words
The method of claim 40 , wherein said placing includes placing a polymer member including a therapeutic agent.
Claim 59
Dependent Claim
20 words
The method of claim 55 , wherein the therapeutic agent is an agent effective to inhibit smooth muscle cell proliferation.
Claim 60
Dependent Claim
22 words
The method of claim 55 , wherein the therapeutic agent is an agent effective to inhibit proliferation or migration of fibroblast cells.
Claim 61
Dependent Claim
25 words
The method of claim 55 , wherein the therapeutic agent is selected from the group consisting of anticoagulants, antiplatlet agents, thrombolytic agents and antibacterial agents.
Claim 62
Dependent Claim
23 words
The method of claim 58 , wherein said thrombolytic agent is selected from the group consisting of urokinase, streptokinase and tissue plasminogen activator.
Claim 63
Dependent Claim
16 words
The method of claim 55 , wherein the agent is paclitaxel or a derivative of paclitaxel.
Claim 64
Dependent Claim
42 words
The method of claim 55 , wherein the therapeutic agent is selected from the group consisting of colchicine, heparin, warfarin, low molecular weight heparin, hirudin, glucocorticoids, angiotensin converting enzyme inhibitors, vincristine, actinomycin, platelet derived growth factor, vascular endothelial growth factor and oligonucleotides.
Claim 65
Dependent Claim
14 words
The method of claim 55 , wherein the therapeutic agent is a topoisomerase inhibitor.
Claim 66
Dependent Claim
17 words
The method of claim 62 , wherein the topoisomerase inhibitor is camptothecin or an analogue of camptothecin.
Claim 67
Dependent Claim
16 words
The method of claim 55 , wherein the polymer member further includes a second therapeutic agent.
Claim 68
Dependent Claim
28 words
The method of claim 64 , wherein the therapeutic agent is paclitaxel and the second therapeutic agent is selected from the group consisting of camptothecin, colchicine and dexamethasone.
Claim 69
Dependent Claim
18 words
The method of claim 40 , wherein said securing includes securing end sleeves composed of a biocompatible metal.
Claim 70
Dependent Claim
30 words
The method of claim 66 , wherein the metal is selected from the group consisting of stainless steel, titanium, tungsten, tantalum, gold, platinum, cobalt, iridium and alloys of these materials.
Claim 71
Dependent Claim
13 words
The method of claim 66 , wherein the metal is a shape-memory alloy.
Claim 72
Dependent Claim
13 words
The method of claim 66 , wherein the metal is coated with polytetrafluoroethylene.
Claim 73
Dependent Claim
17 words
The method of claim 40 , wherein said securing includes securing end sleeves composed of a polymer.
Claim 74
Dependent Claim
18 words
The method of claim 40 , wherein said securing includes securing end sleeves composed of an elastic polymer.
Claim 75
Dependent Claim
17 words
The method of claim 40 , wherein said securing includes securing end sleeves composed of a copolymer.
Claim 76
Dependent Claim
13 words
The method of claim 70 , wherein the polymer is a memory polymer.
Claim 77
Dependent Claim
15 words
The method of claim 73 , wherein the memory polymer is formed of a copolymer.
Claim 78
Dependent Claim
26 words
The method of claim 40 , wherein said securing includes securing the end sleeves on the ends of the polymer-covered support stent by a mechanical means.
Claim 79
Dependent Claim
26 words
The method of claim 40 , wherein said securing includes securing the end sleeves on the ends of the polymer-covered support stent by a biocompatible adhesive.
Claim 80
Independent Claim
81 words
A method for achieving substantially uniform radial expansion in a stent of a selected axial length and having a polymer tubular member coaxially disposed about the stent, comprising, providing tubular end sleeves disposed around each end of the stent, said end sleeves each having an internal surface in contact with the polymer tubular member and an external surface exposed, said end sleeves being radially expandable with the stent to an expanded diameter and covering 50% or less of the stent length.
Claim 81
Independent Claim
81 words
A method for achieving substantially uniform radial expansion in a stent of a selected axial length and having a polymer tubular member coaxially disposed about the stent, comprising, providing tubular end sleeves disposed around each end of the stent, said end sleeves each having an internal surface in contact with the polymer tubular member and an external surface exposed, said end sleeves being radially expandable with the stent to an expanded diameter and covering 50% or less of the stent length.
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