US5972027A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Porous stent drug delivery system
Assignee: Boston Scientific Scimed Inc
•
Filing: 1997-09-30
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Granted: 1999-10-26
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Expires: 2017-09-30
Abstract
Abstract Expandable intraluminal stents made of a powdered metal or polymer are provided as well their method of manufacture. These stents are characterized by a desired porosity, with a drug compressed into the pores of the stent. The stents are formed by subjecting one or more powdered materials in a die cavity to a pressure treatment followed by a heat treatment. The material may be cast directly in a stent-like form or cast into sheets or tubes from which the inventive stents are produced. The so-formed porous metal or polymer stent is then loaded with one or more drugs.
Inventors
- 👤 Michael W. Johnson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:40
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/82; A61L; A61L31/00; A61L31/02; A61L31/022; A61L31/04; A61L31/048; A61L31/14; A61L31/146; A61L31/16; B; B23; B23K; B23K26/00; B23K26/36; B23K26/40; C; C08; C08L; C08L27/00; C08L27/02; C08L27/12; C08L27/18; A61F2/86; A61F2/88; A61F2/90; A61F2/91; A61F2/92; A61F2250/00; A61F2250/0058; A61F2250/0067; A61L2300/00; A61L2300/60; A61L2300/606; A61L2300/608; B23K2103/00; B23K2103/02; B23K2103/04; B23K2103/05; B23K2103/08; B23K2103/14; B23K2103/18; B23K2103/26; B23K2103/30; B23K2103/42; B23K2103/50; Y; Y10; Y10T; Y10T29/00; Y10T29/49; Y10T29/49995
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
158 words
An expandable intraluminal stent comprising a main body portion having a first end, a second end and a flow passage defined therethrough, the main body portion being sized for intraluminal placement within a body passage and subsequent expansion for implantation, at least a portion of the main body portion formed of at least one material having pores therein, the material having been formed from at least one powdered metal, the stent comprising at least two separate regions arranged along the length of the stent, the first region formed of a first material having first pores within, the first material characterized by a first porosity and a first mean pore size, the first material having been formed from a first powdered metal, the second region formed of a second material having second pores within, the second material characterized by a second porosity and a second mean pore size, the second material having been formed from a second powdered metal.
Claim 2
Dependent Claim
158 words
An expandable intraluminal stent comprising a main body portion having a first end, a second end and a flow passage defined therethrough, the main body portion being sized for intraluminal placement within a body passage and subsequent expansion for implantation, at least a portion of the main body portion formed of at least one material having pores therein, the material having been formed from at least one powdered metal, the stent comprising at least two separate regions arranged along the length of the stent, the first region formed of a first material having first pores within, the first material characterized by a first porosity and a first mean pore size, the first material having been formed from a first powdered metal, the second region formed of a second material having second pores within, the second material characterized by a second porosity and a second mean pore size, the second material having been formed from a second powdered metal.
Claim 3
Dependent Claim
25 words
The stent of claim 1 wherein at least one of the first and second regions has a porosity of twenty to eighty percent by volume.
Claim 4
Dependent Claim
31 words
The stent of claim 2 wherein at least one of the first and second regions has a porosity of between forty and sixty percent of the total volume of the metal.
Claim 5
Dependent Claim
19 words
The stent of claim 1 formed of a plurality of strands of a metal, the metal having pores therein.
Claim 6
Dependent Claim
22 words
The stent of claim 1 wherein the stent is coated with one or more layers of one or more drug containing materials.
Claim 7
Dependent Claim
15 words
The stent of claim 1 wherein the first or second powdered metal is stainless steel.
Claim 8
Dependent Claim
19 words
The stent of claim 6 wherein the pores in the first and second materials contain at least one drug.
Claim 9
Dependent Claim
34 words
The stent of claim 7 wherein the drug is selected from the group consisting of smooth muscle cell inhibitors, collagen inhibitors, vasodilators, anti-platelet substances, anti-thrombotic substances, anti-coagulants, cholesterol reducing agents, angiogenics and combinations thereof.
Claim 10
Dependent Claim
21 words
The stent of claim 1 wherein the first pores contain a first drug and the second pores contain a second drug.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2002-10-25 | 2003-04-26 | 2003-10-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2006-10-25 | 2007-04-26 | 2007-10-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2010-10-25 | 2011-04-26 | 2011-10-26 | $7700.00 | Window Closed / Lapsed |