Patent US6165199A successfully refreshed from Google Patents.
US6165199A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Medical device for removing thromboembolic material from cerebral arteries and methods of use
Assignee: Zoll Circulation Inc
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Filing: 1999-01-12
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Granted: 2000-12-26
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Expires: 2019-01-12
Abstract
Abstract The invention provides a medical device having an elongate catheter, a balloon occluder mounted on a distal end of the catheter, and optionally a chopping mechanism associated with an aspiration port of the catheter. Continuous or intermittent suction can be applied to the aspiration port which is distal to the occluder to dislodge thromboembolic material in a carotid or cerebral artery. Oxygenated blood or other fluid, which may be hypothermic, can be perfused through at least one perfusion port proximal to the occluder to maintain and augment perfusion of the collateral vasculature proximal to the occlusive lesion. The flow rate of blood or fluid can be controlled by rotating two cylindrical members. Neuroprotective agents or t-PA can also be infused distal to the occluder through the aspiration port or an infusing port. Methods of using the devices in treating patients with acute stroke or occlusive cerebrovascular disease are also disclosed.
Inventors
- 👤 Denise Barbut
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 06:05
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/22; A61B17/32; A61B17/3205; A61B17/3207; A61B17/320758; A61B2017/22051; A61B2017/22065; A61B2017/22067; A61B2017/22082; A61B2017/320716
Claims Analysis
Total Claims: 31
Claim 1
Independent Claim
139 words
A medical device for removing thromboembolic material from a carotid artery or any other extracranial or intracranial artery, comprising: an elongate catheter having a proximal end, a distal end, and a lumen therebetween communicating with an aspiration port at the distal end, the catheter further comprising first and second concentric cylindrical members and a perfusion lumen communicating with one or more perfusion ports, whereby relative rotation of the first and second members causes the perfusion ports on the first member to align with the perfusion ports on the second member; a balloon occluder mounted on the distal end of the catheter proximal the aspiration port and distal the one or more perfusion ports; and a chopping mechanism associated with the aspiration port, wherein thromboembolic material engaged by suction through the aspiration port is chopped and aspirated through the catheter.
Claim 2
Dependent Claim
139 words
A medical device for removing thromboembolic material from a carotid artery or any other extracranial or intracranial artery, comprising: an elongate catheter having a proximal end, a distal end, and a lumen therebetween communicating with an aspiration port at the distal end, the catheter further comprising first and second concentric cylindrical members and a perfusion lumen communicating with one or more perfusion ports, whereby relative rotation of the first and second members causes the perfusion ports on the first member to align with the perfusion ports on the second member; a balloon occluder mounted on the distal end of the catheter proximal the aspiration port and distal the one or more perfusion ports; and a chopping mechanism associated with the aspiration port, wherein thromboembolic material engaged by suction through the aspiration port is chopped and aspirated through the catheter.
Claim 3
Dependent Claim
14 words
The medical device of claim 1, wherein the balloon occluder comprises an elastomeric balloon.
Claim 4
Dependent Claim
16 words
The medical device of claim 1, wherein the balloon occluder communicates with a balloon inflation lumen.
Claim 5
Dependent Claim
20 words
The medical device of claim 1, wherein the proximal end of the catheter is adapted for attachment to a vacuum.
Claim 6
Dependent Claim
22 words
The medical device of claim 1, wherein the aspiration port and lumen are adapted for infusion of fluid, blood, and pharmaceutical agents.
Claim 7
Dependent Claim
13 words
The medical device of claim 5, wherein the pharmaceutical agent is a vasodilator.
Claim 8
Dependent Claim
19 words
The medical device of claim 6, wherein the vasodilator is selected from the group consisting of nifedipine and nitroprusside.
Claim 9
Dependent Claim
12 words
The medical device of claim 5, wherein the pharmaceutical agent is t-PA.
Claim 10
Dependent Claim
20 words
The medical device of claim 1, further comprising an additional lumen and port for infusion of blood and pharmaceutical agent.
Claim 11
Dependent Claim
15 words
The medical device of claim 1, further comprising a manometer distal to the balloon occluder.
Claim 12
Dependent Claim
15 words
The medical device of claim 1, wherein the chopping mechanism comprises an abrasive grinding surface.
Claim 13
Dependent Claim
19 words
The medical device of claim 1, wherein the chopping mechanism comprises a rotatable blade which operates within a housing.
Claim 14
Dependent Claim
19 words
The medical device of claim 12, wherein the catheter further comprises a second balloon occluder proximal the perfusion ports.
Claim 15
Independent Claim
100 words
A method for removing thromboembolic material from a carotid or cerebral artery, comprising the steps of: providing a catheter having a proximal end, a distal end, an expandable occluder mounted on the distal end, an aspiration port distal the occluder, an aspiration lumen communicating with the port, and a chopping mechanism; inserting the distal end of the catheter into the artery; expanding the occluder to occlude the artery; applying a negative pressure to the aspiration port, wherein the thromboembolic material is engaged by the port; and operating the chopping mechanism to remove at least a portion of the thromboembolic material.
Claim 16
Independent Claim
100 words
A method for removing thromboembolic material from a carotid or cerebral artery, comprising the steps of: providing a catheter having a proximal end, a distal end, an expandable occluder mounted on the distal end, an aspiration port distal the occluder, an aspiration lumen communicating with the port, and a chopping mechanism; inserting the distal end of the catheter into the artery; expanding the occluder to occlude the artery; applying a negative pressure to the aspiration port, wherein the thromboembolic material is engaged by the port; and operating the chopping mechanism to remove at least a portion of the thromboembolic material.
Claim 17
Dependent Claim
14 words
The method of claim 14, wherein the carotid artery is the common carotid artery.
Claim 18
Dependent Claim
23 words
The method of claim 14, wherein the carotid artery is selected from the group consisting of the internal carotid artery and carotid siphon.
Claim 19
Dependent Claim
13 words
The method of claim 14, wherein the artery is the middle cerebral artery.
Claim 20
Dependent Claim
13 words
The method of claim 14, wherein the artery is the anterior cerebral artery.
Claim 21
Dependent Claim
17 words
The method of claim 14, wherein the occluder is a balloon which communicates with an inflation lumen.
Claim 22
Dependent Claim
22 words
The method of claim 14, wherein the catheter further comprises an additional lumen and port for infusion of blood and pharmaceutical agent.
Claim 23
Dependent Claim
13 words
The method of claim 14, wherein chopping mechanism comprises an abrasive grinding surface.
Claim 24
Dependent Claim
18 words
The method of claim 14, wherein the chopping mechanism comprises a rotatable blade which operates within a housing.
Claim 25
Dependent Claim
21 words
The method of claim 14, further comprising the step of infusing pharmaceutical agent into the carotid artery through the aspiration port.
Claim 26
Dependent Claim
12 words
The method of claim 23, wherein the pharmaceutical agent is a vasodilator.
Claim 27
Dependent Claim
18 words
The method of claim 24, wherein the vasodilator is selected from the group consisting of nifedipine and nitroprusside.
Claim 28
Dependent Claim
11 words
The method of claim 23, wherein the pharmaceutical agent is t-PA.
Claim 29
Dependent Claim
16 words
The method of claim 14, further comprising the step of localizing the atheroma with intravascular ultrasound.
Claim 30
Dependent Claim
17 words
The method of claim 14, further comprising the step of localizing the thromboembolic material with carotid doppler.
Claim 31
Dependent Claim
21 words
The method of claim 14, further comprising the step of localizing the thromboembolic material and direction of flow with transcranial doppler.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2003-12-26 | 2004-06-26 | 2004-12-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2007-12-26 | 2008-06-26 | 2008-12-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2011-12-26 | 2012-06-26 | 2012-12-26 | $7700.00 | Window Closed / Lapsed |