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US6146686A Expired / Lapsed US ⏱️ 0.0 years remaining

Implant material and process for using it

Assignee: OctoPlus Sciences BV
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Filing: 1999-04-23
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Granted: 2000-11-14
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Expires: 2019-04-23
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Abstract

Abstract The invention provides a nanotechnology process for implant surface treatment for producing an implant article. The nanotechnology process comprises subjecting a non-porous material to a mechanical or chemical surface treatment until a surface roughness with an average peak distance (Ra value) between 10 and 1,000 nm is obtained. The roughened surface can subsequently be subjected to precipitation of calcium phosphate from a solution containing calcium and phosphate ions.

Inventors

  • 👤 Eugenia Ribeiro de Sousa Fildago Leitao

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-31 04:15
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/28; A61L27/30; A61L27/32; A61F; A61F2/00; A61F2/02; A61F2/30; A61F2/30767; A61L27/02; A61L27/04; A61L27/06; A61F2002/30001; A61F2002/30667; A61F2002/30677; A61F2002/30906; A61F2310/00; A61F2310/00005; A61F2310/00011; A61F2310/00023; A61F2310/00179; A61F2310/00389; A61F2310/00592; A61F2310/00796; A61F2310/0097; A61F2310/00976; A61L2400/00; A61L2400/18

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 53 words
A process for producing a calcium phosphate coated implantable device, comprising subjecting a porous or non-porous material to a surface treatment until a roughened surface with an average peak distance between about 10 nm and about 1,000 nm is obtained and in vitro coating the surface with a layer of a calcium phosphate.
Claim 2
Dependent Claim 53 words
A process for producing a calcium phosphate coated implantable device, comprising subjecting a porous or non-porous material to a surface treatment until a roughened surface with an average peak distance between about 10 nm and about 1,000 nm is obtained and in vitro coating the surface with a layer of a calcium phosphate.
Claim 3
Dependent Claim 15 words
The process according to claim 1, wherein said surface treatment comprises a mechanical abrading treatment.
Claim 4
Dependent Claim 39 words
The process according to claim 1, wherein said surface treatment comprises a chemical treatment including subjecting the surface to acidic, alkaline or oxidizing solutions or a combination of an acidic solution or an alkaline solution and an oxidizing solution.
Claim 5
Dependent Claim 26 words
The process according to claim 1, wherein the roughened surface is subsequently subjected to precipitation of calcium phosphate from a solution containing calcium and phosphate ions.
Claim 6
Dependent Claim 15 words
The process according to claim 4, wherein said solution has a pH of about 4-10.
Claim 7
Dependent Claim 23 words
A process according to claim 1 comprising treating titanium or a titanium alloy with an acid solution followed immersion in an alkaline solution.
Claim 8
Dependent Claim 21 words
A process according to claim 1 comprising treating porous tantalum with an acid solution followed by immersion in an oxidizing solution.
Claim 9
Dependent Claim 15 words
A process according to claim 5 wherein the pH is about 6 to about 8.

References Cited (Backward Citations)

US4330891A Cited
US4746532A Cited
US5141576A Cited
US5205921A Cited
US5478237A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2003-11-14 2004-05-15 2004-11-14 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2007-11-14 2008-05-15 2008-11-14 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2011-11-14 2012-05-15 2012-11-14 $7700.00 Window Closed / Lapsed

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