Patent US6135971A successfully refreshed from Google Patents.
US6135971A
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US
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Apparatus for deposition of ultrasound energy in body tissue
Assignee: The Brigham and Women's Hospital Inc
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Filing: 1996-11-08
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Granted: 2000-10-24
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Expires: 2016-11-08
Abstract
Abstract An apparatus for providing ultrasonic energy for deposition in body tissue including an array of elements having at least two different sizes and at least one element being aperiodically spaced with the respect to other elements in the array. Excitation of the elements produces a beam of ultrasonic energy having reduced grating lobes. Reduced grating lobe magnitude permits improved ultrasonic beam focusing and/or the use of larger element sizes.
Inventors
- 👤 Erin Hutchinson
- 👤 Mark Buchanan
- 👤 Kullervo Hynynen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 02:19
CPC Classifications
B; B06; B06B; B06B1/00; B06B1/02; B06B1/06; B06B1/0607; B06B1/0622; B06B1/0633; A; A61; A61N; A61N7/00; A61N7/02; B06B1/0629; A61B; A61B17/00; A61B17/22; A61B17/22004; A61B2017/22027; A61B2017/22028; A61M; A61M37/00; A61M37/0092; A61N2007/0056; A61N2007/0065; A61N2007/0078; A61N2007/0086; A61N2007/0095
Claims Analysis
Total Claims: 39
Claim 1
Independent Claim
69 words
An apparatus for ultrasonic energy deposition in body tissue comprising: an array of elements having at least two different sizes, at least one element being aperiodically spaced with the respect to other elements; and an excitation means coupled to said plurality of elements for providing said elements with electrical excitations, whereby excitation of said elements produces a beam of ultrasonic energy having reduced grating lobes in said body tissue.
Claim 2
Independent Claim
69 words
An apparatus for ultrasonic energy deposition in body tissue comprising: an array of elements having at least two different sizes, at least one element being aperiodically spaced with the respect to other elements; and an excitation means coupled to said plurality of elements for providing said elements with electrical excitations, whereby excitation of said elements produces a beam of ultrasonic energy having reduced grating lobes in said body tissue.
Claim 3
Dependent Claim
26 words
The apparatus of claim 1 wherein at least one element among all elements having the same size is aperiodically spaced with the respect to other elements.
Claim 4
Dependent Claim
33 words
The apparatus of claim 1 wherein said elements include a first element size and a second element size, said first element size being at least five percent smaller than said second element size.
Claim 5
Dependent Claim
34 words
The apparatus of claim 3 wherein at least one element of said first element size and at least one element of said second element size is aperiodically spaced with the respect to other elements.
Claim 6
Dependent Claim
22 words
The apparatus of claim 3 wherein at least ten percent of said elements are aperiodically spaced with the respect to other elements.
Claim 7
Dependent Claim
22 words
The apparatus of claim 3 wherein at least twenty-five percent of said elements are aperiodically spaced with the respect to other elements.
Claim 8
Dependent Claim
21 words
The apparatus of claim 3 wherein approximately one half of said elements are periodically spaced with the respect to other elements.
Claim 9
Dependent Claim
29 words
The apparatus of claim 3 wherein an average center of mass-to-center of mass spacing of adjacent elements is greater than a half of a wavelength of said ultrasonic energy.
Claim 10
Dependent Claim
15 words
The apparatus of claim 3 wherein said array includes a single row of said elements.
Claim 11
Dependent Claim
16 words
The apparatus of claim 3 wherein said array is a two dimensional arrangement of said elements.
Claim 12
Dependent Claim
20 words
The apparatus of claim 3 wherein said array is two dimensional and includes at least two rows of said elements.
Claim 13
Dependent Claim
16 words
The apparatus of claim 3 wherein said array is a three dimensional arrangement of said elements.
Claim 14
Dependent Claim
20 words
The apparatus of claim 3 wherein said arrangement is three dimensional and includes at least two rows of said elements.
Claim 15
Dependent Claim
13 words
The apparatus of claim 3 further comprising a spacer located between adjacent elements.
Claim 16
Dependent Claim
25 words
The apparatus of claim 14 wherein said spacer size is uniform such that edges of said elements are evenly spaced from edges of adjacent elements.
Claim 17
Dependent Claim
25 words
The apparatus of claim 14 wherein said spacer size is non-uniform such that edges of said elements are non-evenly spaced from edges of adjacent elements.
Claim 18
Dependent Claim
23 words
The apparatus of claim 3 wherein an arrangement of said elements in said array is derived from a method of optimized random distribution.
Claim 19
Dependent Claim
54 words
The apparatus of claim 17 wherein said method of optimized random distribution comprises steps of deriving a cost function and calculating a value of said cost function for a plurality of random element sizes and positions, thereby obtaining a random distribution of cost function values from which to optimize said arrangement of said elements.
Claim 20
Dependent Claim
24 words
The apparatus of claim 18 wherein said cost function includes a quotient of a maximum focusing power and a maximum corresponding grating lobe power.
Claim 21
Dependent Claim
47 words
The apparatus of claim 1 wherein said elements include a first element size and a second element size, a top surface of an element of said first element size being at least five percent smaller than a top surface of an element of said second element size.
Claim 22
Dependent Claim
19 words
The apparatus of claim 2 wherein said at least two elements are aperiodically spaced with respect to other elements.
Claim 23
Dependent Claim
22 words
The apparatus of claim 1 wherein said ultrasonic energy emitted from said elements has a frequency of approximately 0.1 to 100 MHz.
Claim 24
Dependent Claim
39 words
The apparatus of claim 1 further comprising a phase shifting means coupled to said excitation means for providing said elements with electrical excitations having adjustable phases in order to apply said beam to a region of said body tissue.
Claim 25
Dependent Claim
20 words
The apparatus of claim 23 wherein said phase shifting means steers said beam through an angle up to ninety degrees.
Claim 26
Dependent Claim
26 words
The apparatus of claim 24 wherein said phase shifting means steers said beam to at least two distinct focal positions within said region of body tissue.
Claim 27
Dependent Claim
31 words
The apparatus of claim 25 wherein said excitation means includes an apodization means for independently controlling an amplitude, a phase and a frequency of said electrical excitations provided to each element.
Claim 28
Dependent Claim
31 words
The apparatus of claim 26 wherein said apodization means includes a profile optimization method for controlling said beam to provide a substantially uniform temperature profile within said region of body tissue.
Claim 29
Dependent Claim
27 words
The apparatus of claim 27 wherein said profile optimization method includes steps of selecting foci weighing factors and calculating a cost function for said foci weighing factors.
Claim 30
Dependent Claim
46 words
The apparatus of claim 23 further comprising an magnetic resonance imaging means for providing an image of said body tissue coupled to said excitation means and said phase shifting means whereby said excitation means and said phase shifting means are controllable in response to said image.
Claim 31
Independent Claim
93 words
An apparatus for producing localized energy deposition in body tissue comprising: a plurality of radiating elements of at least two different sizes each having a center of mass and at least one of said elements being oriented such that a center of mass-to-center of mass distance between said at least one element and adjacent elements is irregular; and an excitation mechanism coupled to said plurality of elements for providing said elements with electrical excitations, whereby excitation of said elements produces a beam of ultrasonic energy having reduced grating lobes in said body tissue.
Claim 32
Independent Claim
93 words
An apparatus for producing localized energy deposition in body tissue comprising: a plurality of radiating elements of at least two different sizes each having a center of mass and at least one of said elements being oriented such that a center of mass-to-center of mass distance between said at least one element and adjacent elements is irregular; and an excitation mechanism coupled to said plurality of elements for providing said elements with electrical excitations, whereby excitation of said elements produces a beam of ultrasonic energy having reduced grating lobes in said body tissue.
Claim 33
Independent Claim
92 words
An apparatus for producing localized energy deposition in body tissue comprising: a plurality of radiating elements each element having one of two or more different sizes; an array of said plurality of elements having spacers between adjacent elements wherein among elements of substantially the same size at least one of said same-size elements is aperiodically spaced; and an excitation mechanism coupled to said plurality of elements for providing said elements with electrical excitations, whereby excitation of said elements produces a beam of ultrasonic energy having reduced grating lobes in said body tissue.
Claim 34
Independent Claim
92 words
An apparatus for producing localized energy deposition in body tissue comprising: a plurality of radiating elements each element having one of two or more different sizes; an array of said plurality of elements having spacers between adjacent elements wherein among elements of substantially the same size at least one of said same-size elements is aperiodically spaced; and an excitation mechanism coupled to said plurality of elements for providing said elements with electrical excitations, whereby excitation of said elements produces a beam of ultrasonic energy having reduced grating lobes in said body tissue.
Claim 35
Dependent Claim
23 words
The apparatus of claim 1 wherein said excitation means comprises an excitation mechanism that independently controls said electrical excitations provided to each element.
Claim 36
Dependent Claim
35 words
The apparatus of claim 32 wherein said excitation mechanism includes an apodization means for independently controlling at least one of an amplitude, a phase and a frequency of said electrical excitations provided to each element.
Claim 37
Independent Claim
107 words
An apparatus for ultrasonic energy deposition in body tissue comprising: an array of elements having parallelepiped geometry with at least two different sizes, at least one element being aperiodically spaced with the respect to other elements; an excitation mechanism independently coupled to said plurality of elements for providing each of said elements with electrical excitations; and an phase shifting mechanism coupled to said excitation mechanism for independently controlling at least one of an amplitude, a phase and a frequency of said electrical excitations provided to each element, whereby electrical excitation of said elements produces a beam of ultrasonic energy having reduced grating lobes in said body tissue.
Claim 38
Independent Claim
107 words
An apparatus for ultrasonic energy deposition in body tissue comprising: an array of elements having parallelepiped geometry with at least two different sizes, at least one element being aperiodically spaced with the respect to other elements; an excitation mechanism independently coupled to said plurality of elements for providing each of said elements with electrical excitations; and an phase shifting mechanism coupled to said excitation mechanism for independently controlling at least one of an amplitude, a phase and a frequency of said electrical excitations provided to each element, whereby electrical excitation of said elements produces a beam of ultrasonic energy having reduced grating lobes in said body tissue.
Claim 39
Dependent Claim
12 words
The apparatus of claim 1 wherein said elements have a parallelepiped geometry.
References Cited (Backward Citations)
US4052723A
Cited
US4166967A
Cited
US5097844A
Cited
US4586512A
Cited
US4646756A
Cited
US4549553A
Cited
US4776086A
Cited
US4797682A
Cited
US4960107A
Cited
US4860752A
Cited
SU1630854A1
Cited
US4938217A
Cited
US4890268A
Cited
US5091893A
Cited
US5164920A
Cited
US5186181A
Cited
US5343211A
Cited
US5251645A
Cited
US5441532A
Cited
US5327895A
Cited
US5233673A
Cited
US5278757A
Cited
US5295484A
Cited
US5385544A
Cited
US5391197A
Cited
US5327884A
Cited
US5323779A
Cited
US5307812A
Cited
US5488956A
Cited
US5537367A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2003-10-24 | 2004-04-24 | 2004-10-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2007-10-24 | 2008-04-24 | 2008-10-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2011-10-24 | 2012-04-24 | 2012-10-24 | $7700.00 | Window Closed / Lapsed |