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US6096030A Expired / Lapsed US ⏱️ 0.0 years remaining

Light delivery catheter and PDT treatment method

Assignee: Pharmacyclics LLC
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Filing: 1997-09-23
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Granted: 2000-08-01
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Expires: 2017-09-23
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Abstract

Abstract A light delivery catheter (2), for use in PDT treatments, includes a hollow sheath (4) with a balloon (24) at its distal end. Target tissue (33) at a target site on a hollow body organ, such as a blood vessel, is inoculated with an appropriate photosensitizing agent. A light guide (14) extends along the sheath and has a light-radiating portion or light source (20) at its end within the balloon. The balloon is positioned at the target site and target tissue is irradiated causing destruction of the target tissue. The balloon defines perfusion channels (30) when the balloon is inflated so that during use fluid can continue passing through the blood vessel. The light irradiating the vessel wall is preferably of generally equal intensity. This can be achieved in whole or in part in several different ways.

Inventors

  • 👤 Mark V. Ortiz

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 06:43
CPC Classifications
A; A61; A61N; A61N5/00; A61N5/06; A61N5/0613; A61N5/062; A61N5/0601; A61B; A61B18/00; A61B18/18; A61B18/20; A61B18/22; A61B2018/2255; A61B2018/2261

Claims Analysis

Total Claims: 25
Claim 1
Independent Claim 110 words
A light delivery catheter comprising: a sheath defining a lumen: a balloon mounted to the sheath in fluid communication with the lumen; said balloon having a plurality of outwardly extending arms, said balloon at least partially defining at least one perfusion channel between said arms and a balloon interior when the balloon is inflated so that fluid can continue to pass through a hollow body organ when the balloon is inflated within the hollow body organ; and a light guide, said light guide having a light-radiating portion at least partially within the balloon so that light passing alone said light guide is radiated from said light-radiating portion into said balloon.
Claim 2
Dependent Claim 110 words
A light delivery catheter comprising: a sheath defining a lumen: a balloon mounted to the sheath in fluid communication with the lumen; said balloon having a plurality of outwardly extending arms, said balloon at least partially defining at least one perfusion channel between said arms and a balloon interior when the balloon is inflated so that fluid can continue to pass through a hollow body organ when the balloon is inflated within the hollow body organ; and a light guide, said light guide having a light-radiating portion at least partially within the balloon so that light passing alone said light guide is radiated from said light-radiating portion into said balloon.
Claim 3
Dependent Claim 14 words
The catheter according to claim 1 wherein the light guide comprises an optical fiber.
Claim 4
Dependent Claim 24 words
The catheter according to claim 1 wherein the balloon further comprises at least one optical feedback detector for light level monitoring within the balloon.
Claim 5
Dependent Claim 16 words
The catheter according to claim 1 wherein the light radiating portion comprises a cylindrical light diffuser.
Claim 6
Dependent Claim 18 words
The catheter according to claim 4 wherein the cylindrical light diffuser is a separate component from the balloon.
Claim 7
Dependent Claim 21 words
The catheter according to claim 1 wherein the light-radiating portion of said light guide is fully housed within the balloon interior.
Claim 8
Dependent Claim 16 words
The catheter according to claim 1 wherein the light guide comprises a plurality of light-radiating portions.
Claim 9
Dependent Claim 27 words
The catheter according to claim 1 wherein said balloon interior comprises a central region and a plurality of arm regions, said arm regions defined by said arms.
Claim 10
Dependent Claim 14 words
The catheter according to claim 1 wherein said arms extend radially and tangentially outwardly.
Claim 11
Dependent Claim 12 words
The catheter according to claim 1 wherein said arms extend radially outwardly.
Claim 12
Dependent Claim 17 words
The catheter according to claim 1 wherein at least one said arm has a generally Y-cross-sectional shape.
Claim 13
Dependent Claim 14 words
The catheter according to claim 1 wherein said arms have enlarged, pressure-reducing distal ends.
Claim 14
Dependent Claim 15 words
The catheter according to claim 1 wherein said light guide is housed within said lumen.
Claim 15
Dependent Claim 24 words
The catheter according to claim 1 wherein the balloon comprises light-diffusing material to diffuse light from said light-radiating portion passing through said light-diffusing material.
Claim 16
Dependent Claim 16 words
The catheter according to claim 1 further comprising means for equalizing radiation intensity from the balloon.
Claim 17
Dependent Claim 16 words
The catheter according to 1 further comprising light diffusing material as a part of the balloon.
Claim 18
Dependent Claim 16 words
The catheter according to 1 further comprising light diffusing material as a part of the balloon.
Claim 19
Dependent Claim 23 words
The catheter according to claim 1 further comprising a plurality of said light-radiating portions which helps to equalize radiation intensity from the balloon.
Claim 20
Dependent Claim 26 words
The catheter according to 1 further comprising a light-diffusing material within a fluid within the balloon interior which helps to equalize radiation intensity from the balloon.
Claim 21
Dependent Claim 26 words
The catheter according to 1 further comprising a light-diffusing material within a fluid within the balloon interior which helps to equalize radiation intensity from the balloon.
Claim 22
Dependent Claim 110 words
A light delivery catheter comprising: a sheath defining a lumen; a balloon mounted to the sheath in fluid communication with the lumen; said balloon defining at least one perfusion channel and a balloon interior when the balloon is inflated so that fluid can continue to pass through a hollow body organ when the balloon is inflated within the hollow body organ; a light guide, said light guide having a light-radiating portion at least partially within the balloon so that light passing along said light guide is radiated from said light-radiating portion into said balloon; and radiation-absorbing material along selected sections of the balloon which equalizes radiation intensity from the balloon.
Claim 23
Dependent Claim 110 words
A light delivery catheter comprising: a sheath defining a lumen; a balloon mounted to the sheath in fluid communication with the lumen; said balloon defining at least one perfusion channel and a balloon interior when the balloon is inflated so that fluid can continue to pass through a hollow body organ when the balloon is inflated within the hollow body organ; a light guide, said light guide having a light-radiating portion at least partially within the balloon so that light passing along said light guide is radiated from said light-radiating portion into said balloon; and radiation-absorbing material along selected sections of the balloon which equalizes radiation intensity from the balloon.
Claim 24
Dependent Claim 132 words
A light delivery catheter comprising: a sheath defining a lumen; a balloon mounted to the sheath in fluid communication with the lumen; said balloon defining at least one perfusion channel and a balloon interior when the balloon is inflated so that fluid can continue to pass through a hollow body organ when the balloon is inflated within the hollow body organ; a light guide, said light guide having a light-radiating portion at least partially within the balloon so that light passing alone said light guide is radiated from said light-radiating portion into said balloon; said balloon having radially outwardly-extending arms at least partially defining said at least one perfusion channel, said arms having distal ends; and radiation-absorbing material at said distal ends of said arms which equalizes radiation intensity from the balloon.
Claim 25
Dependent Claim 132 words
A light delivery catheter comprising: a sheath defining a lumen; a balloon mounted to the sheath in fluid communication with the lumen; said balloon defining at least one perfusion channel and a balloon interior when the balloon is inflated so that fluid can continue to pass through a hollow body organ when the balloon is inflated within the hollow body organ; a light guide, said light guide having a light-radiating portion at least partially within the balloon so that light passing alone said light guide is radiated from said light-radiating portion into said balloon; said balloon having radially outwardly-extending arms at least partially defining said at least one perfusion channel, said arms having distal ends; and radiation-absorbing material at said distal ends of said arms which equalizes radiation intensity from the balloon.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2003-08-01 2004-01-31 2004-08-01 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2007-08-01 2008-01-31 2008-08-01 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2011-08-01 2012-01-31 2012-08-01 $7700.00 Window Closed / Lapsed

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