US6001067A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Device and method for determining analyte levels
Assignee: Dexcom Inc
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Filing: 1997-03-04
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Granted: 1999-12-14
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Expires: 2017-03-04
Abstract
Abstract Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices, that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices comprise a unique microarchitectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.
Inventors
- 👤 Mark C. Shults
- 👤 Stuart J. Updike
- 👤 Rathbun K. Rhodes
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 07:20
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/145; A61B5/1468; A61B5/1486; A61B5/14865; A61B5/0002; A61B5/0004; A61B5/14532; A61B5/1495; C; C12; C12Q; C12Q1/00; C12Q1/001; C12Q1/005; C12Q1/006
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
116 words
A device for measuring glucose in a biological fluid, comprising: a) a housing comprising electronic circuit means and at least two electrodes operably connected to said electronic circuit means; and b) a sensor means operably connected to said electrodes of said housing, said sensor means comprising i) means for determining the amount of glucose in a biological sample, said glucose determining means operably associated with said electrodes and comprising a membrane impregnated with an oxidase, ii) a bioprotective membrane, said bioprotective membrane positioned more distal to said housing than said glucose determining means and substantially impermeable to macrophages, and iii) an angiogenic layer, said angiogenic layer positioned more distal to said housing than said bioprotective membrane.
Claim 2
Independent Claim
116 words
A device for measuring glucose in a biological fluid, comprising: a) a housing comprising electronic circuit means and at least two electrodes operably connected to said electronic circuit means; and b) a sensor means operably connected to said electrodes of said housing, said sensor means comprising i) means for determining the amount of glucose in a biological sample, said glucose determining means operably associated with said electrodes and comprising a membrane impregnated with an oxidase, ii) a bioprotective membrane, said bioprotective membrane positioned more distal to said housing than said glucose determining means and substantially impermeable to macrophages, and iii) an angiogenic layer, said angiogenic layer positioned more distal to said housing than said bioprotective membrane.
Claim 3
Dependent Claim
14 words
The biological fluid measuring device of claim 1, wherein said oxidase is glucose oxidase.
Claim 4
Dependent Claim
26 words
The biological fluid measuring device of claim 1, wherein said bioprotective membrane further comprises pores having diameters ranging from about 0.1 micron to about 1.0 micron.
Claim 5
Dependent Claim
26 words
The biological fluid measuring device of claim 3, wherein said pores of said bioprotective membrane have diameters ranging from about 0.2 micron to about 0.5 micron.
Claim 6
Dependent Claim
14 words
The biological fluid measuring device of claim 1, wherein said bioprotective membrane comprises polytetrafluoroethylene.
Claim 7
Dependent Claim
14 words
The biological fluid measuring device of claim 1, wherein said angiogenic layer comprises polytetrafluoroethylene.
Claim 8
Dependent Claim
26 words
The biological fluid measuring device of claim 1, further comprising c) means for securing said device to biological tissue, said securing means associated with said housing.
Claim 9
Dependent Claim
15 words
The biological fluid measuring device of claim 7, wherein said securing means comprises poly(ethylene terephthalate).
Claim 10
Dependent Claim
24 words
The biological fluid measuring device of claim 1, wherein said housing further comprises means for transmitting data to a location external to said device.
Claim 11
Dependent Claim
17 words
The biological fluid measuring device of claim 9, wherein said data transmitting means comprises a radiotelemetric device.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2002-12-13 | 2003-06-14 | 2003-12-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2006-12-13 | 2007-06-14 | 2007-12-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2010-12-13 | 2011-06-14 | 2011-12-14 | $7700.00 | Window Closed / Lapsed |