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US5941250A Expired / Lapsed US ⏱️ 0.0 years remaining

Retinal tissue implantation method

Assignee: University of Louisville Research Foundation ULRF
•
Filing: 1997-11-17
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Granted: 1999-08-24
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Expires: 2017-11-17
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Abstract

Abstract The disclosure relates to a method and instrument for implanting retinal tissue into the subretinal space of the eye comprising the steps of inducting a fragment of retinal tissue into a tubular nozzle of an instrument by retracting a mandrel telescoped internally of the nozzle, incising the pars plana region of the eye, incising the retina of the eye to expose a subretinal target area, inserting the nozzle of the instrument through the incisions in the pars plana and retina of the eye, orientating an open end of the nozzle over the target area of the retina, and retracting the nozzle relative to the mandrel of the instrument to deposit the tissue in the target area of the eye.

Inventors

  • 👤 Robert B. Aramant
  • 👤 Magdalene J. Seiler

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 22:15
CPC Classifications
A; A61; A61F; A61F9/00; A61F9/007; A61F9/00727; Y; Y10; Y10S; Y10S623/00; Y10S623/902; Y10S623/905

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 110 words
A method of implanting retinal tissue into the subretinal space of the eye comprising the steps of: encapsulating a fragment of retinal tissue in a protective gel; inducting said tissue into an open end of a tubular nozzle having an internal mandrel; incising the pars plana region of the eye; incising the retina of the eye to expose a subretinal target area; inserting said nozzle through the incisions in the pars plana and retina of the eye; orientating the open end of said nozzle over the target, area of the retina; and retracting said nozzle relative to said mandrel to deposit said tissue in the target area of the eye.
Claim 2
Independent Claim 110 words
A method of implanting retinal tissue into the subretinal space of the eye comprising the steps of: encapsulating a fragment of retinal tissue in a protective gel; inducting said tissue into an open end of a tubular nozzle having an internal mandrel; incising the pars plana region of the eye; incising the retina of the eye to expose a subretinal target area; inserting said nozzle through the incisions in the pars plana and retina of the eye; orientating the open end of said nozzle over the target, area of the retina; and retracting said nozzle relative to said mandrel to deposit said tissue in the target area of the eye.
Claim 3
Independent Claim 135 words
A method of implanting retinal tissue into the subretinal space of the eye comprising the steps of: encapsulating a fragment of retinal tissue in a protective gel; orientating an open end of a tubular nozzle adjacent said retinal tissue; retracting a mandrel disposed internally of said nozzle away from the open end thereof so as to induct said tissue into the open end of said tubular nozzle; incising the pars plana region of the eye; incising the retina of the eye to expose a subretinal target area; inserting said nozzle through the incisions in the pars plana and retina of the eye; orientating the open end of said nozzle over the target area of the retina; and retracting said nozzle relative to said mandrel to deposit said tissue in the target area of the eye.
Claim 4
Independent Claim 135 words
A method of implanting retinal tissue into the subretinal space of the eye comprising the steps of: encapsulating a fragment of retinal tissue in a protective gel; orientating an open end of a tubular nozzle adjacent said retinal tissue; retracting a mandrel disposed internally of said nozzle away from the open end thereof so as to induct said tissue into the open end of said tubular nozzle; incising the pars plana region of the eye; incising the retina of the eye to expose a subretinal target area; inserting said nozzle through the incisions in the pars plana and retina of the eye; orientating the open end of said nozzle over the target area of the retina; and retracting said nozzle relative to said mandrel to deposit said tissue in the target area of the eye.

References Cited (Backward Citations)

US4955889A Cited
US5817075A Cited
US5108421A Cited
US5468246A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2002-08-23 2003-02-22 2003-08-24 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2006-08-23 2007-02-22 2007-08-24 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2010-08-23 2011-02-22 2011-08-24 $7700.00 Window Closed / Lapsed

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