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US5938600A Expired / Lapsed US ⏱️ 0.0 years remaining

Method and device for heating by means of ultrasound

Assignee: US Philips Corp
•
Filing: 1996-12-09
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Granted: 1999-08-17
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Expires: 2016-12-09
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Abstract

Abstract A method of heating a target region by ultrasound radiation includes determination of a position of the target region by a magnetic resonance method. The device for carrying out this method includes an ultrasound device and an MR device. By determining movement of the target region utilizing the MR device (100) and an appropriate magnetic resonance method, and by coupling the movement information to the ultrasound device (118) by an electric signal (122, 124), it is achieved that the ultrasound device can be controlled by the movement information. Various possibilities exist for controlling the ultrasound device. According to a first possibility, the focal region is adjusted to be situated within the target region in order to generate ultrasound. Another possibility is to determine from the movement information the instant at which the target region is situated within the focal region of the ultrasound and to generate ultrasound exclusively for a brief subsequent period during which the focal region is still within the target region. Another possibility is to refrain from generating ultrasound when the movement speed is too high. Finally, the movement information can also be used for making the focal region follow the target region during the generation of ultrasound.

Inventors

  • 👤 Johannes J. Van Vaals
  • 👤 Lennart Hofland

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-06 04:43
CPC Classifications
A; A61; A61N; A61N7/00; A61N7/02; G; G01; G01R; G01R33/00; G01R33/20; G01R33/44; G01R33/48; G01R33/4804; A61B; A61B90/00; A61B90/36; A61B90/37; A61B2090/374; G01R33/54; G01R33/56; G01R33/563

Claims Analysis

Total Claims: 23
Claim 1
Independent Claim 127 words
A method of irradiating a moving target region within a body by ultrasound comprising: performing by a magnetic resonance (MR) device the steps of generating and receiving MR signals in the body, processing the received MR signals, determining automatically movement of the moving target region from the processed MR signals and, generating automatically from the determined movement a control signal representing the determined movement of the moving target region, performing by an ultrasound device the step of irradiating automatically the body with ultrasound, the ultrasound device being responsive to the generated control signal so that a focal region of the ultrasound is in the moving target region, and repeating the prior steps in order that the focal region of the ultrasound remains within the moving target region.
Claim 2
Independent Claim 127 words
A method of irradiating a moving target region within a body by ultrasound comprising: performing by a magnetic resonance (MR) device the steps of generating and receiving MR signals in the body, processing the received MR signals, determining automatically movement of the moving target region from the processed MR signals and, generating automatically from the determined movement a control signal representing the determined movement of the moving target region, performing by an ultrasound device the step of irradiating automatically the body with ultrasound, the ultrasound device being responsive to the generated control signal so that a focal region of the ultrasound is in the moving target region, and repeating the prior steps in order that the focal region of the ultrasound remains within the moving target region.
Claim 3
Dependent Claim 14 words
The method of claim 1 wherein the generated MR signals comprise first navigator signals.
Claim 4
Dependent Claim 21 words
The method of claim 2 wherein said step of determining movement comprises detecting an edge in the processed MR navigator signals.
Claim 5
Dependent Claim 54 words
The method of claim 2 wherein the first MR navigator signals are flow-sensitive, wherein the MR signals further comprise second flow-compensated MR navigator signals, and wherein said step of determining movement further comprises determining a speed of a moving region in the moving target region from the received first and second MR navigator signals.
Claim 6
Dependent Claim 36 words
The method of claim 2 wherein said step of generating the MR navigator signals comprises generating 2D RF pulses for exciting spins in the moving target region, and applying magnetic field gradients to the excited spins.
Claim 7
Dependent Claim 18 words
The method of claim 1 wherein the generated control signal represents a position of the moving target region.
Claim 8
Dependent Claim 28 words
The method of claim 6 wherein said step of irradiating comprises adjusting automatically the focal region of the ultrasound to a position represented by the generated control signal.
Claim 9
Dependent Claim 20 words
The method of claim 1 wherein said step of processing of the received MR signal comprises reconstructing an MR image.
Claim 10
Dependent Claim 18 words
The method of claim 8 wherein the MR signals are generated using a fast MR imaging pulse sequence.
Claim 11
Dependent Claim 17 words
The method of claim 8 wherein said step of determining movement comprises segmenting a reconstructed MR image.
Claim 12
Dependent Claim 23 words
The method of claim 1 wherein the control signal represents when the focal region of the ultrasound is in the moving target region.
Claim 13
Dependent Claim 51 words
The method of claim 11 wherein said step of generating a control signal comprises determining automatically a period during which the focal region of the ultrasound is situated within the moving target region, and wherein said step of irradiating comprises generating at least one ultrasound pulse during the period thus determined.
Claim 14
Dependent Claim 18 words
The method of claim 1 wherein the generated control signal represents a speed of the moving target region.
Claim 15
Independent Claim 111 words
A device for irradiating a moving target region within a body by ultrasound comprising: a magnetic resonance (MR) device comprising receiving means for generating and MR signals from the body, means for processing the received MR signals and, means for determining automatically movement of the moving target region from the processed MR signals and for generating automatically from the determined movement a control signal representing the determined movement of the moving target region, and an ultrasound device for generating ultrasound to which the generated control signal is applied and which is responsive to the generated control signal so that a focal region of ultrasound radiation is in the moving target region.
Claim 16
Independent Claim 111 words
A device for irradiating a moving target region within a body by ultrasound comprising: a magnetic resonance (MR) device comprising receiving means for generating and MR signals from the body, means for processing the received MR signals and, means for determining automatically movement of the moving target region from the processed MR signals and for generating automatically from the determined movement a control signal representing the determined movement of the moving target region, and an ultrasound device for generating ultrasound to which the generated control signal is applied and which is responsive to the generated control signal so that a focal region of ultrasound radiation is in the moving target region.
Claim 17
Dependent Claim 23 words
The device of claim 14 wherein said means for determining generates a control signal which represents a position of the moving target region.
Claim 18
Dependent Claim 54 words
The device of claim 15 wherein said ultrasound device comprises a position control input, said ultrasound device being responsive to the position control input so that the focal region of generated ultrasound is at the position presented to the position control input, and the generated control signal being applied to the position control input.
Claim 19
Dependent Claim 33 words
The device of claim 16 wherein said MR device and said ultrasound device further comprise means for functioning repetitively whereby the focal region of ultrasound is repetitively controlled by repetitively generated control signals.
Claim 20
Dependent Claim 32 words
The device of claim 14 wherein said means for determining generates a control signal which represents a trigger reflecting when the focal region of the ultrasound is in the moving target region.
Claim 21
Dependent Claim 48 words
The device of claim 18 wherein said ultrasound device comprises a trigger input, said ultrasound device being responsive to the trigger input so that ultrasound radiation is generated upon presentation of a signal to the trigger input, and the generated control signal being applied to the trigger input.
Claim 22
Dependent Claim 19 words
The device of claim 14 wherein said means for determining comprises means for execution of an edge detection algorithm.
Claim 23
Dependent Claim 19 words
The device of claim 14 wherein said means for determining comprises means for execution of an image segmentation technique.

References Cited (Backward Citations)

US5178135A Cited
US5131392A Cited
EP0558029A2 Cited
EP0614651A1 Cited
US5590653A Cited
US5307812A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2002-08-16 2003-02-15 2003-08-17 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2006-08-16 2007-02-15 2007-08-17 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2010-08-16 2011-02-15 2011-08-17 $7700.00 Window Closed / Lapsed

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