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US5882327A Expired / Lapsed US ⏱️ 0.0 years remaining

Long-term glaucoma drainage implant

Assignee: Louisiana State University
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Filing: 1997-04-17
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Granted: 1999-03-16
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Expires: 2017-04-17
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Abstract

Abstract An implantable ocular device to decrease intraocular pressure by draining aqueous humor from the anterior chamber of the eye into an extraocular space above the sclera and below the conjunctiva and Tenon's layers. The device includes a conduit attached to an episcleral drainage plate having a porous posterior surface for cellular ingrowth and attachment by the sclera. The distal end of the conduit is inserted into the anterior chamber and protrudes out of the limbal/scleral junction. A portion of the outer surface of the conduit adjacent to the plate has a porous ingrowth surface area to enhance anchoring of the conduit to the surrounding extraocular tissues. The plate has a smooth anterior surface and a porous posterior surface. This device uses porous surfaces to enhance cellular infiltration and ingrowth to increase apposition with surrounding tissues, decrease micromovement of the implant, and thereby decrease the fibrous capsule formation surrounding the episcleral plate. Long-term failure of glaucoma drainage devices has been linked to thickening of the filtering bleb due to excessive fibrous capsule formation.

Inventors

  • 👤 Jean T. Jacob

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 22:59
CPC Classifications
A; A61; A61F; A61F9/00; A61F9/007; A61F9/00781

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 125 words
A surgically implantable drainage device to facilitate the flow of aqueous humor from an eye comprising a drainage plate having an anterior surface defining a drainage basin and having a porous posterior surface, wherein said porous posterior surface includes pores having a pore size of about 15 to 90 microns to promote cellular ingrowth and attachment of the device to the sclera of the eye, and a drainage conduit having a proximal end which is attached to and is in fluid communication with the drainage plate and a distal end which is capable of being inserted into the anterior chamber of the eye such that aqueous humor may flow from the anterior chamber of the eye, through the drainage conduit, and onto the drainage plate.
Claim 2
Dependent Claim 125 words
A surgically implantable drainage device to facilitate the flow of aqueous humor from an eye comprising a drainage plate having an anterior surface defining a drainage basin and having a porous posterior surface, wherein said porous posterior surface includes pores having a pore size of about 15 to 90 microns to promote cellular ingrowth and attachment of the device to the sclera of the eye, and a drainage conduit having a proximal end which is attached to and is in fluid communication with the drainage plate and a distal end which is capable of being inserted into the anterior chamber of the eye such that aqueous humor may flow from the anterior chamber of the eye, through the drainage conduit, and onto the drainage plate.
Claim 3
Dependent Claim 25 words
The device of claim 1 wherein said drainage conduit has a porous ingrowth surface to facilitate and promote adherence of the device to the sclera.
Claim 4
Dependent Claim 116 words
A surgically implantable drainage device to facilitate the flow of aqueous humor from an eye, comprising a drainage plate having a non-porous anterior surface defining a drainage basin and a posterior surface, wherein said posterior surface includes pores having a pore size of about 15 to 90 microns to promote cellular ingrowth and attachment of the device to the sclera of the eye; and a drainage conduit having a proximal end which is attached to the drainage plate and a distal end which is capable of being placed in the anterior chamber of the eye such that aqueous humor may flow from the anterior chamber of the eye, through the conduit, and onto the drainage plate.
Claim 5
Dependent Claim 116 words
A surgically implantable drainage device to facilitate the flow of aqueous humor from an eye, comprising a drainage plate having a non-porous anterior surface defining a drainage basin and a posterior surface, wherein said posterior surface includes pores having a pore size of about 15 to 90 microns to promote cellular ingrowth and attachment of the device to the sclera of the eye; and a drainage conduit having a proximal end which is attached to the drainage plate and a distal end which is capable of being placed in the anterior chamber of the eye such that aqueous humor may flow from the anterior chamber of the eye, through the conduit, and onto the drainage plate.
Claim 6
Dependent Claim 19 words
The device of claim 3 wherein said drainage conduit has a porous ingrowth surface adjacent to its proximal end.
Claim 7
Dependent Claim 56 words
The device of claim 4 including a dissolvable drainage plug located in the conduit, and wherein said plug contains drugs which prevent excessive fibrous capsule formation, such that as the plug dissolves the drugs are released and delivered through the conduit, onto the plate and ultimately to the tissues of the eye which surround the bleb.
Claim 8
Dependent Claim 20 words
The device of claim 3 wherein the porous posterior surface of the plate wraps around the side of the plate.
Claim 9
Dependent Claim 39 words
The device of claim 3 wherein the porous posterior surface of the plate includes pores which are encapsulated so as to create porous tunnels having entrances and exits that are located on the posterior surface of the drainage plate.
Claim 10
Dependent Claim 229 words
A surgically implantable drainage device to facilitate the flow of aqueous humor from an eye comprising a pliable drainage plate having a smooth, non-porous anterior surface and a porous posterior surface for cellular ingrowth and attachment of the device to the sclera, a drainage conduit having a proximal end which is attached to the drainage plate and a distal end which is capable of being placed in the anterior chamber of the eye such that aqueous humor may flow from the anterior chamber of the eye, through the conduit, and onto the anterior surface of the plate, wherein said drainage conduit has a porous ingrowth surface adjacent to its proximal end for cellular ingrowth and attachment of the device to the sclera, wherein said drainage plate has a ridge rising above its anterior surface in the general area where the drainage conduit is attached to the plate, said ridge having an opening to permit the drainage conduit to pass therethrough, said ridge preventing fibrous capsule tissue from clogging the drainage conduit, and a dissolvable plug located in the drainage conduit, said plug containing drugs which prevent excess fibrous capsule formation, such that when said surgically implantable drainage device is in use and the plug dissolves, the drugs are released and delivered through the conduit, onto the plate and ultimately to the tissues of the eye which surround the bleb.
Claim 11
Dependent Claim 229 words
A surgically implantable drainage device to facilitate the flow of aqueous humor from an eye comprising a pliable drainage plate having a smooth, non-porous anterior surface and a porous posterior surface for cellular ingrowth and attachment of the device to the sclera, a drainage conduit having a proximal end which is attached to the drainage plate and a distal end which is capable of being placed in the anterior chamber of the eye such that aqueous humor may flow from the anterior chamber of the eye, through the conduit, and onto the anterior surface of the plate, wherein said drainage conduit has a porous ingrowth surface adjacent to its proximal end for cellular ingrowth and attachment of the device to the sclera, wherein said drainage plate has a ridge rising above its anterior surface in the general area where the drainage conduit is attached to the plate, said ridge having an opening to permit the drainage conduit to pass therethrough, said ridge preventing fibrous capsule tissue from clogging the drainage conduit, and a dissolvable plug located in the drainage conduit, said plug containing drugs which prevent excess fibrous capsule formation, such that when said surgically implantable drainage device is in use and the plug dissolves, the drugs are released and delivered through the conduit, onto the plate and ultimately to the tissues of the eye which surround the bleb.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2002-03-15 2002-09-14 2003-03-16 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2006-03-15 2006-09-14 2007-03-16 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2010-03-15 2010-09-14 2011-03-16 $7700.00 Window Closed / Lapsed

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