Patent US5836935A successfully refreshed from Google Patents.
US5836935A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Implantable refillable controlled release device to deliver drugs directly to an internal portion of the body
Assignee: University of Kentucky Research Foundation
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Filing: 1997-01-28
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Granted: 1998-11-17
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Expires: 2017-01-28
Abstract
Abstract An implantable, refillable, rate-controlled drug delivery device, with a hollow reservoir, and a drug delivery tube communicating with the hollow reservoir. The drug delivery tube includes at least one rate-limiting permeable membrane which regulates drug delivery. A method of controlling the delivery of a drug to an internal portion of a body is disclosed.
Inventors
- 👤 Paul Ashton
- 👤 Roy A. Patchell
- 👤 Jon Cooper
- 👤 Byron A. Young
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 17:34
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K9/0024; A61K9/0085; A61M; A61M31/00; A61M31/002; A61M39/00; A61M39/02; A61M39/0208
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
49 words
An implantable, refillable, rate controlled drug delivery device, comprising a hollow reservoir, a drug delivery tube communicating with the hollow reservoir, and one or more rate-limiting elements, said one or more elements consisting essentially of a permeable membrane in said drug delivery tube, which membrane passively regulates drug delivery.
Claim 2
Dependent Claim
49 words
An implantable, refillable, rate controlled drug delivery device, comprising a hollow reservoir, a drug delivery tube communicating with the hollow reservoir, and one or more rate-limiting elements, said one or more elements consisting essentially of a permeable membrane in said drug delivery tube, which membrane passively regulates drug delivery.
Claim 3
Dependent Claim
14 words
The device according to claim 1, wherein said device comprises two rate-limiting permeable membranes.
Claim 4
Dependent Claim
25 words
The device according to claim 1 wherein said rate-limiting permeable membrane is located between the hollow reservoir and an opening of the drug delivery tube.
Claim 5
Dependent Claim
28 words
The device according to claim 1, wherein said hollow reservoir contains a drug to be delivered at a controlled rate to an eternal target area of the body.
Claim 6
Dependent Claim
17 words
The device according to claim 4, wherein said internal target area of the body is the brain.
Claim 7
Dependent Claim
15 words
The device according to claim 1, further comprising a backing member circumscribing the hollow reservoir.
Claim 8
Dependent Claim
13 words
The device according to claim 6, wherein said backing member is a membrane.
Claim 9
Dependent Claim
44 words
A method of controlling the delivery of a anti-tumor drug to an internal portion of a body comprising administering an anti-tumor drug to an internal portion of the body through a device according to claim 1 to control the delivery of the anti-tumor drug.
Claim 10
Dependent Claim
31 words
A method for treating a brain tumor comprising administering an anti-tumor drug to a brain tumor through a device according to claim 1 to regulate drug delivery to the brain tumor.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2001-11-16 | 2002-05-18 | 2002-11-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2005-11-16 | 2006-05-18 | 2006-11-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2009-11-16 | 2010-05-18 | 2010-11-17 | $7700.00 | Window Closed / Lapsed |