US5836935A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Implantable refillable controlled release device to deliver drugs directly to an internal portion of the body
Assignee: University of Kentucky Research Foundation
•
Filing: 1997-01-28
•
Granted: 1998-11-17
•
Expires: 2017-01-28
Abstract
Abstract An implantable, refillable, rate-controlled drug delivery device, with a hollow reservoir, and a drug delivery tube communicating with the hollow reservoir. The drug delivery tube includes at least one rate-limiting permeable membrane which regulates drug delivery. A method of controlling the delivery of a drug to an internal portion of a body is disclosed.
Inventors
- 👤 Paul Ashton
- 👤 Roy A. Patchell
- 👤 Jon Cooper
- 👤 Byron A. Young
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 07:49
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K9/0024; A61K9/0085; A61M; A61M31/00; A61M31/002; A61M39/00; A61M39/02; A61M39/0208
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
49 words
An implantable, refillable, rate controlled drug delivery device, comprising a hollow reservoir, a drug delivery tube communicating with the hollow reservoir, and one or more rate-limiting elements, said one or more elements consisting essentially of a permeable membrane in said drug delivery tube, which membrane passively regulates drug delivery.
Claim 2
Dependent Claim
49 words
An implantable, refillable, rate controlled drug delivery device, comprising a hollow reservoir, a drug delivery tube communicating with the hollow reservoir, and one or more rate-limiting elements, said one or more elements consisting essentially of a permeable membrane in said drug delivery tube, which membrane passively regulates drug delivery.
Claim 3
Dependent Claim
14 words
The device according to claim 1, wherein said device comprises two rate-limiting permeable membranes.
Claim 4
Dependent Claim
25 words
The device according to claim 1 wherein said rate-limiting permeable membrane is located between the hollow reservoir and an opening of the drug delivery tube.
Claim 5
Dependent Claim
28 words
The device according to claim 1, wherein said hollow reservoir contains a drug to be delivered at a controlled rate to an eternal target area of the body.
Claim 6
Dependent Claim
17 words
The device according to claim 4, wherein said internal target area of the body is the brain.
Claim 7
Dependent Claim
15 words
The device according to claim 1, further comprising a backing member circumscribing the hollow reservoir.
Claim 8
Dependent Claim
13 words
The device according to claim 6, wherein said backing member is a membrane.
Claim 9
Dependent Claim
44 words
A method of controlling the delivery of a anti-tumor drug to an internal portion of a body comprising administering an anti-tumor drug to an internal portion of the body through a device according to claim 1 to control the delivery of the anti-tumor drug.
Claim 10
Dependent Claim
31 words
A method for treating a brain tumor comprising administering an anti-tumor drug to a brain tumor through a device according to claim 1 to regulate drug delivery to the brain tumor.
References Cited (Backward Citations)
US3310051A
Cited
US3894538A
Cited
US4273761A
Cited
US4511355A
Cited
US4568331A
Cited
US4681560A
Cited
US4761158A
Cited
US4816016A
Cited
US4588394A
Cited
US4687468A
Cited
US5087616A
Cited
US4871352A
Cited
US5084015A
Cited
US4857053A
Cited
US5011472A
Cited
US4969871A
Cited
US5160320A
Cited
US5051257A
Cited
US5291887A
Cited
US5116493A
Cited
US5180820A
Cited
US5229500A
Cited
US5041107A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2001-11-16 | 2002-05-18 | 2002-11-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2005-11-16 | 2006-05-18 | 2006-11-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2009-11-16 | 2010-05-18 | 2010-11-17 | $7700.00 | Window Closed / Lapsed |