Patent US5830173A successfully refreshed from Google Patents.
US5830173A
Expired / Lapsed
US
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Intravitreal medicine delivery
Assignee: Individual
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Filing: 1997-08-01
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Granted: 1998-11-03
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Expires: 2017-08-01
Abstract
Abstract An intravitreal medicine delivery device and method that includes an implant device through which a wide variety of beneficial medicines including drugs or other pharmacological agents can be introduced into the vitreous cavity over an extended period of time with only a single initial surgery to implant the device. The device and method minimize the surgical incision needed for implantation and avoid future or repeated invasive surgery or procedures. Additional amounts of the initial medicine can readily be introduced or the medication can be varied or changed, as required. Furthermore, the device and method allow the dosage delivered to the vitreous cavity to be controlled, and the device is constructed so as to filter medicines delivered to the cavity and also avoids damage to or interference with other parts of the eye during implantation or during use.
Inventors
- 👤 Robert Logan Avery
- 👤 Jeffrey Kevin Luttrull
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 12:48
CPC Classifications
A; A61; A61F; A61F9/00; A61F9/0008; A61F9/0017; A61M; A61M2210/00; A61M2210/06; A61M2210/0612
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
75 words
A method of delivering medicine to the vitreous cavity of the eye comprising the steps of: establishing a reservoir on the eyewall and under the conjunctiva for holding a supply of a medicine, and providing a passageway between the reservoir and the vitreous cavity and through which medicine can move from the reservoir into the cavity, said passageway also being provided under the conjunctiva so that the entire reservoir and passageway are under the conjunctiva.
Claim 2
Independent Claim
75 words
A method of delivering medicine to the vitreous cavity of the eye comprising the steps of: establishing a reservoir on the eyewall and under the conjunctiva for holding a supply of a medicine, and providing a passageway between the reservoir and the vitreous cavity and through which medicine can move from the reservoir into the cavity, said passageway also being provided under the conjunctiva so that the entire reservoir and passageway are under the conjunctiva.
Claim 3
Dependent Claim
23 words
The method of claim 1 including the further step of intermittently introducing medicine into the reservoir while the reservoir remains on the eyeball.
Claim 4
Dependent Claim
62 words
The method of claim 2 wherein the intermittent introduction of medicine involves the further step of introducing a quantity of medicine into the reservoir greater than a predetermined single dose thereof, and including the further step of enabling such a predetermined dose of medicine to move into the vitreal cavity at selected intervals between said intermittent introductions of medicine into the reservoir.
Claim 5
Dependent Claim
34 words
The method of claim 2 wherein said intermittent introducing step involves the further steps of introducing selectively different types of medicines into the reservoir at different times without removing the reservoir from the eyewall.
Claim 6
Dependent Claim
29 words
The method of claim 1 including the further step of restricting passage of medicine from the reservoir into the vitreous cavity while medicine is being introduced into the reservoir.
Claim 7
Dependent Claim
98 words
The method of claim 1 wherein the establishing step involves suturing an intravitreal medicine delivery device which includes the reservoir and the injection port on the eyewall under the conjunctiva and Tenon's capsule, said device including fluid conducting means and pump means actuatable from externally of the eye, said conducting means having a proximate end connected to the reservoir and a distal end, and wherein the enabling step involves inserting the distal end into the vitreal cavity and subsequently actuating said pump means from externally of the eye to pump fluid from the reservoir into the vitreal cavity.
Claim 8
Independent Claim
108 words
A method of delivering medicine including drugs and other pharmacological agents to the vitreous cavity of the eye involving the use of an implant device which has a reservoir with a reservoir-refilling injection port comprising the steps of implanting the reservoir including the injection port under the conjunctiva and Tenon's capsule of the eye so that the injection port faces anteriorly of the eye and can be seen exteriorly of the eye through the conjunctiva, establishing a connection between the reservoir and the vitreous cavity which allows passage of medicine from the reservoir into the vitreous cavity, and introducing medicine into the reservoir by injection through the port.
Claim 9
Independent Claim
108 words
A method of delivering medicine including drugs and other pharmacological agents to the vitreous cavity of the eye involving the use of an implant device which has a reservoir with a reservoir-refilling injection port comprising the steps of implanting the reservoir including the injection port under the conjunctiva and Tenon's capsule of the eye so that the injection port faces anteriorly of the eye and can be seen exteriorly of the eye through the conjunctiva, establishing a connection between the reservoir and the vitreous cavity which allows passage of medicine from the reservoir into the vitreous cavity, and introducing medicine into the reservoir by injection through the port.
Claim 10
Independent Claim
190 words
A method of delivering medicine to the vitreous cavity of the eye comprising the steps of: establishing a reservoir on the eyewall for holding a supply of a medicine, providing a passageway between the reservoir and the vitreous cavity through which medicine can move from the reservoir into the cavity, wherein the establishing step involves suturing an intravitreal medicine delivery device which includes the reservoir on the eyewall under the conjunctiva and Tenon's capsule, said device including fluid conducting means and pump means actuatable from externally of the eye, said conducting means having a proximate end connected to the reservoir and a distal end, and wherein the enabling step involves inserting the distal end into the vitreal cavity and subsequently actuating said pump means from externally of the eye to pump fluid from the reservoir into the vitreal cavity, and wherein the fluid conducting means includes a resiliently compressible portion which functions as the pump and is actuatable by pressing against the compressible portion, wherein the suturing step involves locating the compressible portion under the eyelid, and wherein said actuating step involves pressing against the compressible portion through the eyelid.
Claim 11
Independent Claim
190 words
A method of delivering medicine to the vitreous cavity of the eye comprising the steps of: establishing a reservoir on the eyewall for holding a supply of a medicine, providing a passageway between the reservoir and the vitreous cavity through which medicine can move from the reservoir into the cavity, wherein the establishing step involves suturing an intravitreal medicine delivery device which includes the reservoir on the eyewall under the conjunctiva and Tenon's capsule, said device including fluid conducting means and pump means actuatable from externally of the eye, said conducting means having a proximate end connected to the reservoir and a distal end, and wherein the enabling step involves inserting the distal end into the vitreal cavity and subsequently actuating said pump means from externally of the eye to pump fluid from the reservoir into the vitreal cavity, and wherein the fluid conducting means includes a resiliently compressible portion which functions as the pump and is actuatable by pressing against the compressible portion, wherein the suturing step involves locating the compressible portion under the eyelid, and wherein said actuating step involves pressing against the compressible portion through the eyelid.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2001-11-02 | 2002-05-04 | 2002-11-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2005-11-02 | 2006-05-04 | 2006-11-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2009-11-02 | 2010-05-04 | 2010-11-03 | $7700.00 | Window Closed / Lapsed |