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Methods of preventing degeneration of myoplasties

Assignee: Thomas Jefferson University
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Filing: 1996-07-18
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Granted: 1998-09-15
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Expires: 2016-07-18
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Abstract

Abstract Methods of reducing the degeneration of a tissue resulting from mobilization with or without chronic, continuous electrical stimulation by administering basic fibroblast growth factor or heparin to the tissue are provided.

Inventors

  • 👤 John D. Mannion
  • 👤 Michael G. Magno

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-10 01:14
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/18; A61K38/1825; A61K31/00; A61K31/70; A61K31/715; A61K31/726; A61K31/727; A61K41/00; A61N; A61N1/00; A61N1/18; A61N1/32; A61N1/36; A61N1/36042; C; C07; C07K; C07K14/00; C07K14/435; C07K14/475; C07K14/50; C07K14/503

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 40 words
A method of reducing the degeneration of a skeletal muscle resulting from mobilization of the tissue comprising administering to the tissue undergoing mobilization an effective amount of basic fibroblast growth factor combined with subjecting said tissue to chronic electrical stimulation.
Claim 2
Independent Claim 40 words
A method of reducing the degeneration of a skeletal muscle resulting from mobilization of the tissue comprising administering to the tissue undergoing mobilization an effective amount of basic fibroblast growth factor combined with subjecting said tissue to chronic electrical stimulation.
Claim 3
Dependent Claim 17 words
The method of claim 1 wherein the basic fibroblast growth factor is administered as a bolus injection.
Claim 4
Independent Claim 37 words
A method of reducing the degeneration of a skeletal muscle resulting from mobilization of the tissue comprising administering to the tissue undergoing mobilization an effective amount of heparin combined with subjecting said tissue to chronic electrical stimulation.
Claim 5
Independent Claim 37 words
A method of reducing the degeneration of a skeletal muscle resulting from mobilization of the tissue comprising administering to the tissue undergoing mobilization an effective amount of heparin combined with subjecting said tissue to chronic electrical stimulation.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2001-09-14 2002-03-16 2002-09-15 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2005-09-14 2006-03-16 2006-09-15 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2009-09-14 2010-03-16 2010-09-15 $7700.00 Window Closed / Lapsed

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