Photodynamic therapy balloon catheter

Claim 2

A photodynamic therapy balloon catheter for activating treatment fluid at a location within a living body, comprising: an elongated tubular catheter having a proximal portion which remains outside of the living body when in use, the catheter also having a distal portion which is inserted into the living body when in use; an optical fiber extending along the length of said catheter, said optical fiber having a generally distal light energy emanating section; said elongated tubular catheter having a light-passing inner tubular member cylindrically surrounding said optical fiber and extending longitudinally along the length of the light energy emanating section of said optical fiber, said inner tubular member being made of a polymer material; a light-passing inflatable balloon member at said distal portion of the catheter, said balloon member being in fluid-passing communication with said proximal portion of the catheter, said balloon member cylindrically surrounding said inner tubular member and extending longitudinally with respect to said inner tubular member, said balloon member being made of a polymeric material; a light source communicating with said optical fiber to deliver light energy to said light energy emanating section; and at least one of said inner tubular member and said balloon member includes light-reflective material which, upon light emanating through the light energy emanating section, reflects said light energy and activates photodynamic treatment fluid at a location within a living body, said light-reflective material being loaded into said polymer material from which said at least one of said inner tubular member and said balloon member is made.

Claim 3

The photodynamic catheter of claim 1, wherein said light-reflective material is present in a quantity so as to disperse the light energy and produce a uniform illumination of light.

Claim 4

The photodynamic catheter of claim 1, wherein said generally distal light energy emanating section extends longitudinally for a distance approximating the length of a cylindrical working surface of the balloon member.

Claim 5

The photodynamic catheter of claim 1, wherein said optical fiber is tapered such that said optical fiber decreases in thickness in the distal direction, and wherein the light emanating from said light energy emanating section of said optical fiber is a uniformly illuminating light.

Claim 6

The photodynamic therapy balloon catheter of claim 1, wherein said inner tubular member is coated with reflective material.

Claim 7

The photodynamic therapy balloon catheter of claim 5, wherein said reflective material is TiO 2 .

Claim 8

The photodynamic therapy balloon catheter of claim 1, wherein said balloon member is coated with reflective material.

Claim 9

The photodynamic therapy balloon catheter of claim 7, wherein said reflective material is TiO 2 .

Claim 10

The photodynamic therapy balloon catheter of claim 1, wherein said reflective material is TiO 2 .

Claim 11

The photodynamic therapy balloon catheter of claim 1, wherein the loaded reflective material is from about 5 to about 40 percent by weight of the total weight of the inner tubular member.

Claim 12

A photodynamic therapy balloon catheter for activating treatment fluid at a location within a living body, comprising: an elongated tubular catheter having a proximal portion which remains outside of the living body when in use, the catheter also having a distal portion which is inserted into the living body when in use; an optical fiber extending along the length of said catheter, said optical fiber having a generally distal light energy emanating section; said elongated tubular catheter having a light-passing inner tubular member cylindrically surrounding said optical fiber and extending longitudinally along the length of the light energy emanating section of said optical fiber; a light-passing inflatable balloon member at said distal portion of the catheter, said balloon member being in fluid-passing communication with said proximal portion of the catheter, said balloon member cylindrically surrounding said inner tubular member and extending longitudinally with respect to said inner tubular member; a light source communicating with said optical fiber to deliver light energy to said light energy emanating section; and said balloon member includes light-reflective material which, upon light emanating through the light energy emanating section, reflects said light energy and activates photodynamic treatment fluid at a location within a living body, and said balloon member is loaded with said reflective material.

Claim 13

A photodynamic therapy balloon catheter for activating treatment fluid at a location within a living body, comprising: an elongated tubular catheter having a proximal portion which remains outside of the living body when in use, the catheter also having a distal portion which is inserted into the living body when in use; an optical fiber extending along the length of said catheter, said optical fiber having a generally distal light energy emanating section; said elongated tubular catheter having a light-passing inner tubular member cylindrically surrounding said optical fiber and extending longitudinally along the length of the light energy emanating section of said optical fiber; a light-passing inflatable balloon member at said distal portion of the catheter, said balloon member being in fluid-passing communication with said proximal portion of the catheter, said balloon member cylindrically surrounding said inner tubular member and extending longitudinally with respect to said inner tubular member; a light source communicating with said optical fiber to deliver light energy to said light energy emanating section; and said balloon member includes light-reflective material which, upon light emanating through the light energy emanating section, reflects said light energy and activates photodynamic treatment fluid at a location within a living body, and said balloon member is loaded with said reflective material.

Claim 14

The photodynamic therapy balloon catheter of claim 1, wherein said reflective material is TiO 2 .

Claim 15

The photodynamic therapy balloon catheter of claim 11, wherein the loaded reflective material is from about 5 to 40 percent by weight of the total weight of the balloon member.

Claim 16

The photodynamic therapy balloon catheter of claim 13, wherein the loaded reflective material is from about 10 to about 40 percent by weight of the total weight of the balloon member.

Claim 17

A photodynamic therapy balloon catheter for activating treatment fluid at a location within a living body, the catheter comprising: an elongated tubular catheter having a proximal portion which remains outside of the living body when in use, the catheter also having a distal portion which is inserted into the living body when in use; an optical fiber extending along the length of said catheter, said optical fiber having a generally distal light energy emanating section; said elongated tubular catheter having a light-passing inner tubular member cylindrically surrounding said optical fiber and extending longitudinally along the length of the light energy emanating section of said optical fiber; a light-passing inflatable balloon member at said distal portion of the catheter, said balloon member being in fluid-passing communication with said proximal portion of the catheter, said balloon member cylindrically surrounding said inner tubular member and extending longitudinally with respect to said inner tubular member; a light-passing fluid material positioned between said inner tubular member and said inflatable balloon member; a light source communicating with said optical fiber to deliver light energy to said light energy emanating section; and at least one of said inner tubular member and said balloon member includes light-reflective material and which, upon light emanating through the light energy emanating section, reflects said light energy and activates photodynamic treatment fluid at a location within a living body, and said at least one of said inner tubular member and said balloon member is made of a polymer loaded with said reflective material.

Claim 18

A photodynamic therapy balloon catheter for activating treatment fluid at a location within a living body, the catheter comprising: an elongated tubular catheter having a proximal portion which remains outside of the living body when in use, the catheter also having a distal portion which is inserted into the living body when in use; an optical fiber extending along the length of said catheter, said optical fiber having a generally distal light energy emanating section; said elongated tubular catheter having a light-passing inner tubular member cylindrically surrounding said optical fiber and extending longitudinally along the length of the light energy emanating section of said optical fiber; a light-passing inflatable balloon member at said distal portion of the catheter, said balloon member being in fluid-passing communication with said proximal portion of the catheter, said balloon member cylindrically surrounding said inner tubular member and extending longitudinally with respect to said inner tubular member; a light-passing fluid material positioned between said inner tubular member and said inflatable balloon member; a light source communicating with said optical fiber to deliver light energy to said light energy emanating section; and at least one of said inner tubular member and said balloon member includes light-reflective material and which, upon light emanating through the light energy emanating section, reflects said light energy and activates photodynamic treatment fluid at a location within a living body, and said at least one of said inner tubular member and said balloon member is made of a polymer loaded with said reflective material.

Claim 19

The photodynamic therapy balloon catheter of claim 15, wherein said at least one of the inner tubular member and the balloon member is coated with reflective material.

Claim 20

The photodynamic therapy balloon catheter of claim 16, wherein said reflective material is TiO 2 .

Claim 21

The photodynamic therapy balloon catheter of claim 15, wherein said reflective material is TiO 2 .

Claim 22

The photodynamic therapy balloon catheter of claim 15, wherein the loaded reflective material is from about 5 to 40 percent by weight of the total weight of the balloon member.

Claim 23

The photodynamic therapy balloon catheter of claim 19, wherein the loaded reflective material is from about 10 to 40 percent by weight of the total weight of the balloon member.

Claim 24

The photodynamic therapy balloon catheter of claim 15, wherein said fluid material contains reflective material.

Claim 25

The photodynamic therapy balloon catheter of claim 21, wherein said reflective material is TiO 2 .

Claim 26

The photodynamic therapy balloon catheter of claim 15, wherein the loaded reflective material is from about 5 to about 40 percent by weight of the total weight of the inner tubular member.

Claim 27

A photodynamic therapy balloon catheter for activating treatment fluid at a location within a living body, the catheter comprising: an elongated tubular catheter having a proximal portion which remains outside of the living body when in use, the catheter also having a distal portion which is inserted into the living body when in use; an optical fiber extending along the length of said catheter, said optical fiber having a generally distal light energy emanating section; said elongated tubular catheter having a light-passing inner tubular member cylindrically surrounding said optical fiber and extending longitudinally along the length of the light energy emanating section of said optical fiber; a light-passing inflatable balloon member at said distal portion of the catheter, said balloon member being in fluid-passing communication with said proximal portion of the catheter, said balloon member cylindrically surrounding said inner tubular member and extending longitudinally with respect to said inner tubular member; a light-passing fluid material positioned between said inner tubular member and said inflatable balloon member; a light source communicating with said optical fiber to deliver light energy to said light energy emanating section; and said balloon member includes light-reflective material and which, upon light emanating through the light energy emanating section, reflects said light energy and activates photodynamic treatment fluid at a location within a living body, and said balloon member is coextruded with reflective material such that said reflective material is positioned between an inner wall and an outer wall of said balloon member.

Claim 28

A photodynamic therapy balloon catheter for activating treatment fluid at a location within a living body, the catheter comprising: an elongated tubular catheter having a proximal portion which remains outside of the living body when in use, the catheter also having a distal portion which is inserted into the living body when in use; an optical fiber extending along the length of said catheter, said optical fiber having a generally distal light energy emanating section; said elongated tubular catheter having a light-passing inner tubular member cylindrically surrounding said optical fiber and extending longitudinally along the length of the light energy emanating section of said optical fiber; a light-passing inflatable balloon member at said distal portion of the catheter, said balloon member being in fluid-passing communication with said proximal portion of the catheter, said balloon member cylindrically surrounding said inner tubular member and extending longitudinally with respect to said inner tubular member; a light-passing fluid material positioned between said inner tubular member and said inflatable balloon member; a light source communicating with said optical fiber to deliver light energy to said light energy emanating section; and said balloon member includes light-reflective material and which, upon light emanating through the light energy emanating section, reflects said light energy and activates photodynamic treatment fluid at a location within a living body, and said balloon member is coextruded with reflective material such that said reflective material is positioned between an inner wall and an outer wall of said balloon member.

Claim 29

The photodynamic therapy balloon catheter of claim 24, wherein said at least one of the inner tubular member and the balloon member is coated with reflective material.

Claim 30

The photodynamic therapy balloon catheter of claim 25, wherein said reflective material is TiO 2 .

Claim 31

A photodynamic therapy balloon catheter for activating treatment fluid at a location within a living body, the catheter comprising: an elongated tubular catheter having a proximal portion which remains outside of the living body when in use, the catheter also having a distal portion which is inserted into the living body when in use; an optical fiber extending along the length of said catheter, said optical fiber having a generally distal light energy emanating section; said elongated tubular catheter having a light-passing inner tubular member cylindrically surrounding said optical fiber and extending longitudinally along the length of the light energy emanating section of said optical fiber; a light-passing inflatable balloon member at said distal portion of the catheter, said balloon member being in fluid-passing communication with said proximal portion of the catheter, said balloon member cylindrically surrounding said inner tubular member and extending longitudinally with respect to said inner tubular member; a light-passing fluid material positioned between said inner tubular member and said inflatable balloon member; a light source communicating with said optical fiber to deliver light energy to said light energy emanating section; and at least one of said inner tubular member and said balloon member includes light-reflective material and which, upon light emanating through the light energy emanating section, reflects said light energy and activates photodynamic treatment fluid at a location within a living body, said at least one of the inner tubular member and the balloon member being made of a polymer loaded with reflective material, and the loaded reflective material is from about 10 to about 40 percent by weight of the total weight of the member.

Claim 32

A photodynamic therapy balloon catheter for activating treatment fluid at a location within a living body, the catheter comprising: an elongated tubular catheter having a proximal portion which remains outside of the living body when in use, the catheter also having a distal portion which is inserted into the living body when in use; an optical fiber extending along the length of said catheter, said optical fiber having a generally distal light energy emanating section; said elongated tubular catheter having a light-passing inner tubular member cylindrically surrounding said optical fiber and extending longitudinally along the length of the light energy emanating section of said optical fiber; a light-passing inflatable balloon member at said distal portion of the catheter, said balloon member being in fluid-passing communication with said proximal portion of the catheter, said balloon member cylindrically surrounding said inner tubular member and extending longitudinally with respect to said inner tubular member; a light-passing fluid material positioned between said inner tubular member and said inflatable balloon member; a light source communicating with said optical fiber to deliver light energy to said light energy emanating section; and at least one of said inner tubular member and said balloon member includes light-reflective material and which, upon light emanating through the light energy emanating section, reflects said light energy and activates photodynamic treatment fluid at a location within a living body, said at least one of the inner tubular member and the balloon member being made of a polymer loaded with reflective material, and the loaded reflective material is from about 10 to about 40 percent by weight of the total weight of the member.

Claim 33

A photodynamic therapy balloon catheter for activating treatment fluid at a location within a living body, comprising: an elongated tubular catheter having a proximal portion which remains outside of the living body when in use, the catheter also having a distal portion which is inserted into the living body when in use; an optical fiber extending along the length of said catheter, said optical fiber having a generally distal light energy emanating section; said elongated tubular catheter having a light-passing inner tubular member cylindrically surrounding said optical fiber and extending longitudinally along the length of the light energy emanating section of said optical fiber; a light-passing inflatable balloon member at said distal portion of the catheter, said balloon member being in fluid-passing communication with said proximal portion of the catheter, said balloon member cylindrically surrounding said inner tubular member and extending longitudinally with respect to said inner tubular member; a light source communicating with said optical fiber to deliver light energy to said light energy emanating section; and said balloon member includes light-reflective material which, upon light emanating through the light energy emanating section, reflects said light energy and activates photodynamic treatment fluid at a location within a living body, and the balloon member is coextruded with reflective material such that said reflective material is positioned between an inner wall and an outer wall of said balloon member.

Claim 34

A photodynamic therapy balloon catheter for activating treatment fluid at a location within a living body, comprising: an elongated tubular catheter having a proximal portion which remains outside of the living body when in use, the catheter also having a distal portion which is inserted into the living body when in use; an optical fiber extending along the length of said catheter, said optical fiber having a generally distal light energy emanating section; said elongated tubular catheter having a light-passing inner tubular member cylindrically surrounding said optical fiber and extending longitudinally along the length of the light energy emanating section of said optical fiber; a light-passing inflatable balloon member at said distal portion of the catheter, said balloon member being in fluid-passing communication with said proximal portion of the catheter, said balloon member cylindrically surrounding said inner tubular member and extending longitudinally with respect to said inner tubular member; a light source communicating with said optical fiber to deliver light energy to said light energy emanating section; and said balloon member includes light-reflective material which, upon light emanating through the light energy emanating section, reflects said light energy and activates photodynamic treatment fluid at a location within a living body, and the balloon member is coextruded with reflective material such that said reflective material is positioned between an inner wall and an outer wall of said balloon member.

Claim 35

A photodynamic therapy balloon catheter for activating treatment fluid at a location within a living body, comprising: an elongated tubular catheter having a proximal portion which remains outside of the living body when in use, the catheter also having a distal portion which is inserted into the living body when in use; an optical fiber extending along the length of said catheter, said optical fiber having a generally distal light energy emanating section; said elongated tubular catheter having a light-passing inner tubular member cylindrically surrounding said optical fiber and extending longitudinally along the length of the light energy emanating section of said optical fiber; a light-passing inflatable balloon member at said distal portion of the catheter, said balloon member being in fluid-passing communication with said proximal portion of the catheter, said balloon member cylindrically surrounding said inner tubular member and extending longitudinally with respect to said inner tubular member; a light source communicating with said optical fiber to deliver light energy to said light energy emanating section; and said inner tubular member includes light-reflective material which, upon light emanating through the light energy emanating section, reflects said light energy and activates photodynamic treatment fluid at a location within a living body, and said inner tubular member being loaded with reflective material, and the loaded reflective material is from about 10 to about 40 percent by weight of the total weight of the inner tubular member.

Claim 36

A photodynamic therapy balloon catheter for activating treatment fluid at a location within a living body, comprising: an elongated tubular catheter having a proximal portion which remains outside of the living body when in use, the catheter also having a distal portion which is inserted into the living body when in use; an optical fiber extending along the length of said catheter, said optical fiber having a generally distal light energy emanating section; said elongated tubular catheter having a light-passing inner tubular member cylindrically surrounding said optical fiber and extending longitudinally along the length of the light energy emanating section of said optical fiber; a light-passing inflatable balloon member at said distal portion of the catheter, said balloon member being in fluid-passing communication with said proximal portion of the catheter, said balloon member cylindrically surrounding said inner tubular member and extending longitudinally with respect to said inner tubular member; a light source communicating with said optical fiber to deliver light energy to said light energy emanating section; and said inner tubular member includes light-reflective material which, upon light emanating through the light energy emanating section, reflects said light energy and activates photodynamic treatment fluid at a location within a living body, and said inner tubular member being loaded with reflective material, and the loaded reflective material is from about 10 to about 40 percent by weight of the total weight of the inner tubular member.