Patent US738161A successfully refreshed from Google Patents.
US5785657A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Blood flow measurement device
Assignee: Pacesetter AB
•
Filing: 1995-01-13
•
Granted: 1998-07-28
•
Expires: 2015-01-13
Abstract
Abstract A blood flow velocity measurement device is devised where there exist such entities within the fluid which are detectable when axially flowing (passing by) an appropriate detector of known and well defined dimensions mounted onto a catheter. The entities produced for instance by a generator, when flowing by the detector, induced a known single response, the response bearing direct correlation to the flow velocity, in the form of direct reciprocity to the velocity and direct proportion to the length of the sensitive length of the detector. Autocorrelation of the function obtained by the overlap and pile-up of successive events is calculated and from the characteristic points in the autocorrelation function the axial velocity is inferred. The measurement is best when the probing beam is perpendicular to the flow.
Inventors
- 👤 Branko Breyer
- 👤 Bozidar Ferek-Petric
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 12:33
CPC Classifications
G; G01; G01F; G01F1/00; G01F1/704; G01F1/708; A; A61; A61B; A61B5/00; A61B5/02; A61B5/026; A61B5/0265; A61B5/027; A61B8/00; A61B8/06; A61B8/12; G01F1/712; G01F1/7086
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
209 words
A blood flow measurement device for measuring a flow perpendicular to a probe beam, comprising: a catheter insertable into a blood vessel in the body of a subject, said catheter having a distal end and a proximal end and a length extending therebetween; at least one detecting device means mounted onto said catheter at a position along said length without impeding insertion of the catheter into the blood vessel, for emitting a probe beam having a directivity characteristic which defines a sensitivity volume for detecting entities flowing through said sensitivity volume and for generating detection signals corresponding to detection of said entities; electronic circuitry means for measuring and performing calculations on the signals generated by said detecting device means to obtain calculation data signals; and evaluation means responsive to said calculation data signals for determining a velocity of flow of said entities therefrom, said electronic circuitry means comprising means for performing time autocorrelation calculations and said evaluation means comprising means for detecting a signal characteristic in said calculation data signals for obtaining a characteristic delay time within an autocorrelation function and for dividing the sensitivity volume in a direction of said flow with said characteristic delay time for identifying a velocity component of the blood flow in said direction.
Claim 2
Dependent Claim
209 words
A blood flow measurement device for measuring a flow perpendicular to a probe beam, comprising: a catheter insertable into a blood vessel in the body of a subject, said catheter having a distal end and a proximal end and a length extending therebetween; at least one detecting device means mounted onto said catheter at a position along said length without impeding insertion of the catheter into the blood vessel, for emitting a probe beam having a directivity characteristic which defines a sensitivity volume for detecting entities flowing through said sensitivity volume and for generating detection signals corresponding to detection of said entities; electronic circuitry means for measuring and performing calculations on the signals generated by said detecting device means to obtain calculation data signals; and evaluation means responsive to said calculation data signals for determining a velocity of flow of said entities therefrom, said electronic circuitry means comprising means for performing time autocorrelation calculations and said evaluation means comprising means for detecting a signal characteristic in said calculation data signals for obtaining a characteristic delay time within an autocorrelation function and for dividing the sensitivity volume in a direction of said flow with said characteristic delay time for identifying a velocity component of the blood flow in said direction.
Claim 3
Dependent Claim
39 words
A blood flow measurement device as claimed in claim 1 wherein said detecting device means comprises an ultrasonic transducer and means for operating said ultrasonic transducer in at least one of a pulse-echo mode and a continuous wave mode.
Claim 4
Dependent Claim
42 words
A blood flow measurement device as claimed in claim 2 wherein said ultrasonic transducer includes a plurality of piezoelectric transducer elements of different geometrical forms which, in combination, produce a defined directivity characteristic, said piezoelectric transducer elements being mounted onto said catheter.
Claim 5
Dependent Claim
41 words
A blood flow measurement device as claimed in claim 3 wherein said catheter has a longitudinal axis along said length thereof and wherein said piezoelectric transducer elements produce a directivity characteristic having an axis disposed substantially perpendicular to said longitudinal axis.
Claim 6
Dependent Claim
44 words
A blood flow measurement device as claimed in claim 4 wherein said means for operating said ultrasound transducer comprise means for operating said ultrasound transducer in said pulse-echo mode with a sensitivity for detecting ultrasound scattered from erythrocytes as said entities in said flow.
Claim 7
Dependent Claim
94 words
A blood flow measurement device as claimed in claim 3 wherein said plurality of piezoelectric transducer elements includes at least one pair of piezoelectric transducer elements, each piezoelectric transducer element in said at least one pair having a directivity characteristic and the respective directivity characteristics of said piezoelectric transducer elements in said at least one pair overlapping and defining a volume outside of said catheter comprising said sensitivity volume, and said piezoelectric transducer elements in said at least one pair each having a longest dimension which extends parallel to said length of said catheter.
Claim 8
Dependent Claim
69 words
A blood flow measurement device as claimed in claim 1 wherein said detecting device means comprise at least one pair of optical transducer elements, each optical transducer element in said pair having respective transmission and reception directivity characteristics, and the respective transmission and reception directivity characteristics of said optical transducers in said at least one pair overlapping and defining a volume outside of said catheter comprising said sensitivity volume.
Claim 9
Dependent Claim
50 words
A blood flow measurement device as claimed in claim 1 wherein said detecting device means comprise ion generator means for generating ions in blood in said blood vessel, and ion detector means, having said sensitivity volume disposed in front thereof, for detecting a density of ions in said sensitivity volume.
Claim 10
Dependent Claim
36 words
A blood flow measurement device as claimed in claim 1 wherein said detector device means comprise magnetic polarization detector means, having said sensitivity volume in front thereof, for detecting magnetically polarized entities in said sensitivity volume.
Claim 11
Dependent Claim
49 words
A blood flow measurement device as claimed in claim 9 wherein said magnetic polarization detector means comprise a ferromagnetic particle detection device having a length defining said sensitivity volume, said ferromagnetic particle detection device detecting a presence or absence of at least one ferromagnetic particle in said sensitivity volume.
Claim 12
Dependent Claim
61 words
A blood flow measurement device as claimed in claim 10 wherein said ferromagnetic particle detection device comprises a north-south polarized pole piece pair which generate a magnetic field in said sensitivity volume, and a pair of detection windings which detect changes in said magnetic field as a result of said at least one ferromagnetic particle entering and leaving said sensitivity volume.
Claim 13
Dependent Claim
83 words
A blood flow measurement device as claimed in claim 11 wherein said detecting device means comprise a light transmission-detection device disposed on a surface of said catheter and containing a plurality of densely packed light sources and detectors, each light source and detector having a directivity characteristic and the respective directivity characteristics of said light sources and detectors overlapping at a defined distance above said surface, and each light source and detector having a substantially inverse square sensitivity characteristic with respect to distance.
Claim 14
Dependent Claim
32 words
A blood flow measurement device as claimed in claim 11 wherein said catheter comprises electrical conductors running along said catheter from said detecting device means to the proximal end of said catheter.
Claim 15
Dependent Claim
27 words
A blood flow measurement device as claimed in claim 13 wherein said catheter comprises electrical connectors respectively terminating said conductors at said proximal end of said catheter.
Claim 16
Dependent Claim
57 words
A blood flow measurement device as claimed in claim 14 wherein said electronic circuitry means is disposed at said proximal end of said catheter, connected to said electrical connectors, and wherein said electronic circuitry means includes means for activating said at least one detecting device means and for detecting electrical signals from the activated detector device means.
Claim 17
Dependent Claim
29 words
A blood flow measurement device as claimed in claim 15 wherein said evaluation means are disposed at said proximal end of said catheter, connected to said electronic circuitry means.
Claim 18
Dependent Claim
27 words
A blood flow measurement device as claimed in claim 1 further comprising display means connected to said evaluation means for displaying a representation of said velocity component.
Claim 19
Dependent Claim
35 words
A blood flow measurement device as claimed in claim 1 further comprising transmission means, connected to said evaluation means, for transmitting a representation of said velocity component to a location remote from said evaluation means.
References Cited (Backward Citations)
US4227407A
Cited
US4265126A
Cited
JPS5770479A
Cited
EP0092841A2
Cited
US4573477A
Cited
US4573477B1
Cited
FR2551213A1
Cited
EP0140726A1
Cited
EP0144968A2
Cited
EP0150672A1
Cited
GB2170972A
Cited
DE3544477A1
Cited
US4744367A
Cited
EP0228070A2
Cited
EP0266998A2
Cited
US4790323A
Cited
US5127418A
Cited
JPH0216139A
Cited
EP0447597A1
Cited
WO1992015239A1
Cited
US5291892A
Cited
US5390677A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2001-07-27 | 2002-01-26 | 2002-07-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2005-07-27 | 2006-01-26 | 2006-07-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2009-07-27 | 2010-01-26 | 2010-07-28 | $7700.00 | Window Closed / Lapsed |