US5783248A
Expired / Lapsed
US
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Process for producing a bioceramic composite material containing natural bone material on an alumina substrate
Assignee: National Science and Technology Council
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Filing: 1995-08-28
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Granted: 1998-07-21
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Expires: 2015-08-28
Abstract
Abstract A process is provided for producing a bioceramic composite in which an alumina based ceramic substrate is coated with an intermediate calcium pyrophosphate layer to cement a porous calcium phosphate material to the alumina based ceramic substrate. In one aspect of the invention, the porous calcium phosphate material is a porous lattice made from natural bone. A bioceramic composite which includes an alumina-based ceramic substrate, an intermediate calcium pyrophosphate layer and a porous natural bone material bonded to the intermediate calcium pyrophosphate layer is also disclosed.
Inventors
- 👤 Ruey-Mo Lin
- 👤 Nan-Chung Wu
- 👤 Kuang-Hsing Liu
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 17:35
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/36; A61L27/3683; A61L27/3691; A61L27/02; A61L27/10; A61L27/105; A61L27/3604; A61L27/3608; A61L27/3641; A61L27/3645; A61L27/365; A61L27/40; A61L27/42; A61L27/425; C; C04; C04B; C04B35/00; C04B35/01; C04B35/10; C04B35/111; C04B35/117; C04B35/622; C04B35/62222; C04B37/00; C04B37/003; C04B37/005; C04B41/00; C04B41/009; C04B41/45; C04B41/50; C04B41/5025; C04B41/5048; C04B41/80; C04B41/81; C04B41/85; C04B41/87; C04B2111/00; C04B2111/00474; C04B2111/00637; C04B2111/00836; C04B2237/00; C04B2237/02; C04B2237/04; C04B2237/06; C04B2237/30; C04B2237/32; C04B2237/34; C04B2237/343; C04B2237/36; C04B2237/363; C04B2237/50; C04B2237/70; C04B2237/704; C04B2237/708
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
95 words
A process for producing a bioceramic composite comprising: a) preparing an alumina based ceramic substrate; b) forming on said substrate a layer of calcium phosphate material; c) heating a natural bone material in an amount sufficient to obtain a porous natural bone material; d) coating said porous natural bone material with a calcium phosphate material; e) placing said coated porous natural bone material on said layer of calcium phosphate material on said substrate to form a composite and thereafter sintering said composite to bond said porous natural bone material to said alumina based ceramic substrate.
Claim 2
Dependent Claim
95 words
A process for producing a bioceramic composite comprising: a) preparing an alumina based ceramic substrate; b) forming on said substrate a layer of calcium phosphate material; c) heating a natural bone material in an amount sufficient to obtain a porous natural bone material; d) coating said porous natural bone material with a calcium phosphate material; e) placing said coated porous natural bone material on said layer of calcium phosphate material on said substrate to form a composite and thereafter sintering said composite to bond said porous natural bone material to said alumina based ceramic substrate.
Claim 3
Dependent Claim
53 words
The process of claim 1, wherein said layer of calcium phosphate material is a layer of calcium pyrophosphate and is formed on the substrate by applying to the substrate a coating composition consisting essentially of calcium metaphosphate and then sintering the coated substrate to form a layer of calcium pyrophosphate on said substrate.
Claim 4
Dependent Claim
19 words
The process of claim 2, wherein the calcium pyrophosphate layer has a thickness of from 30 to 150 μm.
Claim 5
Dependent Claim
16 words
The process of claim 1, wherein the natural bone material is heated at about 700° C.
Claim 6
Dependent Claim
19 words
The process of claim 4, wherein the natural bone material is heated at about 700° C. for eight hours.
Claim 7
Dependent Claim
21 words
The process of claim 1, wherein the porous natural bone material is coated with a composition consisting essentially of calcium metaphosphate.
Claim 8
Dependent Claim
32 words
The process of claim 1, wherein the composite of the alumina based ceramic substrate and the coated porous natural bone material is sintered at a temperature of from 1000° to 1250° C.
Claim 9
Dependent Claim
17 words
The process of claim 7, wherein the composite is sintered at a temperature of about 1100° C.
Claim 10
Dependent Claim
72 words
A process for producing a bioceramic composite comprising: a) preparing an alumina based ceramic substrate; b) heating a natural bone material in an amount sufficient to obtain a porous natural bone material; c) joining said porous natural bone material to said alumina based ceramic substrate with a calcium phosphate material to form a composite and thereafter sintering said composite to bond said porous natural bone material to said alumina based ceramic substrate.
Claim 11
Dependent Claim
72 words
A process for producing a bioceramic composite comprising: a) preparing an alumina based ceramic substrate; b) heating a natural bone material in an amount sufficient to obtain a porous natural bone material; c) joining said porous natural bone material to said alumina based ceramic substrate with a calcium phosphate material to form a composite and thereafter sintering said composite to bond said porous natural bone material to said alumina based ceramic substrate.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2001-07-20 | 2002-01-19 | 2002-07-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2005-07-20 | 2006-01-19 | 2006-07-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2009-07-20 | 2010-01-19 | 2010-07-21 | $7700.00 | Window Closed / Lapsed |