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US5769790A Expired / Lapsed US ⏱️ 0.0 years remaining

Focused ultrasound surgery system guided by ultrasound imaging

Assignee: Insightec Ltd
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Filing: 1996-10-25
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Granted: 1998-06-23
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Expires: 2016-10-25
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Abstract

Abstract A system employing ultrasound imaging as a method to localize a patient's tissue volume to be treated prior to applying therapeutic levels of ultrasound energy includes a therapy transducer for producing high-intensity fields that cause necrosis and an imaging transducer for producing high-quality ultrasound images. The therapy transducer is a spheroidal piezoelectric element and the imaging transducer is made up of a plurality of piezoelectric elements mounted in fixed relationship to the therapy transducer. The therapy transducer transmits a beam that is focused at a location in the tissue to be treated. The imaging transducer is then steered to produce successive receive beams which scan the tissue, including the tissue at the focal point of the pulsed therapy transducer. The image of the focal point is then superimposed on an image of the tissue to be treated obtained by B-mode imaging using the imaging transducer to transmit and then receive. Proper alignment of the focal point and the tissue to be treated ensures proper positioning of the therapy transducer relative to the patient.

Inventors

  • 👤 Ronald Dean Watkins
  • 👤 Christopher Mark William Daft

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-09 01:13
CPC Classifications
A; A61; A61B; A61B8/00; A61B8/08; A61N; A61N7/00; A61N7/02; A61B17/00; A61B17/22; A61B17/225; A61B17/2256; A61B5/00; A61B5/48; A61B5/4887; A61B5/489; A61B8/06; A61B8/13

Claims Analysis

Total Claims: 16
Claim 1
Independent Claim 205 words
A method for employing ultrasound imaging to guide focused ultrasound surgery, comprising the steps of: positioning a probe, including an ultrasonic therapy transducer and an ultrasonic imaging transducer, relative to a patient such that a focal point of the therapy transducer is located in tissue of the patient, said transducers being in fixed positional relationship to each other; operating said imaging transducer in transmit and receive modes to acquire data sufficient to form an image of tissue to undergo necrosis; displaying an image of said tissue to undergo necrosis; applying relatively low electrical energy to said therapy transducer, said relatively low electrical energy having an amplitude and duration to cause ultrasound energy to be transmitted by said therapy transducer to the focal point at a level that is insufficient to cause necrosis of tissue at the focal point; operating said imaging transducer in the receive mode to acquire data sufficient to form an image of an artifact representing ultrasound energy scattered by the tissue at said focal point in response to application of said relatively low electrical energy to said therapy transducer; displaying an image of said artifact; and registering said image of said artifact relative to said image of said tissue to undergo necrosis.
Claim 2
Independent Claim 205 words
A method for employing ultrasound imaging to guide focused ultrasound surgery, comprising the steps of: positioning a probe, including an ultrasonic therapy transducer and an ultrasonic imaging transducer, relative to a patient such that a focal point of the therapy transducer is located in tissue of the patient, said transducers being in fixed positional relationship to each other; operating said imaging transducer in transmit and receive modes to acquire data sufficient to form an image of tissue to undergo necrosis; displaying an image of said tissue to undergo necrosis; applying relatively low electrical energy to said therapy transducer, said relatively low electrical energy having an amplitude and duration to cause ultrasound energy to be transmitted by said therapy transducer to the focal point at a level that is insufficient to cause necrosis of tissue at the focal point; operating said imaging transducer in the receive mode to acquire data sufficient to form an image of an artifact representing ultrasound energy scattered by the tissue at said focal point in response to application of said relatively low electrical energy to said therapy transducer; displaying an image of said artifact; and registering said image of said artifact relative to said image of said tissue to undergo necrosis.
Claim 3
Dependent Claim 79 words
The method of claim 1 and further comprising the step of applying relatively high electrical energy to said therapy transducer when said artifact and images indicate that said focal point is located at said tissue to undergo necrosis, said relatively high electrical energy having an amplitude and duration to cause ultrasound energy to be transmitted by said therapy transducer to the focal point at a level that is sufficient to cause necrosis of the tissue at the focal point.
Claim 4
Dependent Claim 95 words
The method as defined in claim 1 and further comprising the steps of: determining the position of said artifact relative to said tissue to undergo necrosis; adjusting the probe position relative to the patient until said artifact coincides with said tissue to undergo necrosis; and applying relatively high electrical energy to said therapy transducer, said relatively high electrical energy having an amplitude and duration to cause ultrasound energy to be transmitted by said therapy transducer to the focal point at a level that is sufficient to cause necrosis of the tissue at said focal point.
Claim 5
Independent Claim 144 words
A method for employing ultrasound imaging to guide focused ultrasound surgery, comprising the steps of: positioning a probe, including an ultrasonic therapy transducer and an ultrasonic imaging transducer, relative to a patient such that a focal point of the therapy transducer is located in tissue of the patient, said transducers being in fixed positional relationship to each other; applying relatively low electrical energy to the therapy transducer, said relatively low electrical energy having an amplitude and duration such that ultrasound energy transmitted by the therapy transducer to the focal point in response thereto is insufficient to cause necrosis of tissue at the focal point; and controlling a plurality of elements of the imaging transducer to form a receive beam of ultrasound energy scattered by the tissue at the focal point in response to application of said relatively low electrical energy to the therapy transducer.
Claim 6
Independent Claim 144 words
A method for employing ultrasound imaging to guide focused ultrasound surgery, comprising the steps of: positioning a probe, including an ultrasonic therapy transducer and an ultrasonic imaging transducer, relative to a patient such that a focal point of the therapy transducer is located in tissue of the patient, said transducers being in fixed positional relationship to each other; applying relatively low electrical energy to the therapy transducer, said relatively low electrical energy having an amplitude and duration such that ultrasound energy transmitted by the therapy transducer to the focal point in response thereto is insufficient to cause necrosis of tissue at the focal point; and controlling a plurality of elements of the imaging transducer to form a receive beam of ultrasound energy scattered by the tissue at the focal point in response to application of said relatively low electrical energy to the therapy transducer.
Claim 7
Dependent Claim 70 words
The method of claim 4 and further comprising the step of applying relatively high electrical energy to the therapy transducer after the step of controlling a plurality of elements of the imaging transducer, said relatively high electrical energy having an amplitude and duration such that ultrasound energy transmitted by the therapy transducer to the focal point in response thereto is sufficient to cause necrosis of tissue at the focal point.
Claim 8
Dependent Claim 90 words
The method of claim 4 wherein the step of controlling a plurality of elements of the imaging transducer comprises the steps of: controlling a plurality of elements of the imaging transducer to form a transmit beam of ultrasound energy directed at tissue to be treated; controlling a plurality of elements of the imaging transducer to form a receive beam of ultrasound energy scattered by the tissue to be treated in response to said transmit beam; and determining the position of said focal point relative to said tissue to be treated.
Claim 9
Dependent Claim 97 words
The method of claim 6 and further comprising the steps of: adjusting the position of the probe relative to the patient after the step of determining the position of said focal point relative to said tissue to be treated, until said focal point coincides with said tissue to be treated; and applying relatively high electrical energy to the therapy transducer, said relatively high electrical energy having an amplitude and duration such that ultrasound energy transmitted by the therapy transducer to the focal point in response thereto is sufficient to cause necrosis of the tissue to be treated.
Claim 10
Independent Claim 72 words
A system for performing focused ultrasound surgery guided by ultrasound imaging, comprising: a probe including an ultrasonic therapy transducer and an ultrasonic imaging transducer arranged in a predetermined fixed positional relationship to each other; a pulsing circuit coupled to said imaging transducer; a receiving circuit coupled to said imaging transducer; a therapy generator; and means for selectively providing energization to said therapy transducer from either said therapy generator or said pulsing circuit.
Claim 11
Independent Claim 72 words
A system for performing focused ultrasound surgery guided by ultrasound imaging, comprising: a probe including an ultrasonic therapy transducer and an ultrasonic imaging transducer arranged in a predetermined fixed positional relationship to each other; a pulsing circuit coupled to said imaging transducer; a receiving circuit coupled to said imaging transducer; a therapy generator; and means for selectively providing energization to said therapy transducer from either said therapy generator or said pulsing circuit.
Claim 12
Dependent Claim 14 words
The system of claim 8, wherein said therapy transducer comprises a spheroidal piezoelectric element.
Claim 13
Dependent Claim 19 words
The system of claim 8, wherein said imaging transducer is situated at the center of said spheroidal piezoelectric element.
Claim 14
Dependent Claim 16 words
The system of claim 8, wherein said imaging transducer is situated outside said spheroidal piezoelectric element.
Claim 15
Dependent Claim 25 words
The system of claim 8 and further comprising a positioning system mechanically linked to said probe for moving said probe relative to a stationary target.
Claim 16
Dependent Claim 34 words
The system of claim 8 and further comprising a display monitor, and a processor for forming an image on said display monitor in response to receipt by said imaging transducer of scattered ultrasound energy.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2001-06-22 2001-12-22 2002-06-23 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2005-06-22 2005-12-22 2006-06-23 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2009-06-22 2009-12-22 2010-06-23 $7700.00 Window Closed / Lapsed

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