US5686089A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Tissue moisturizing and antimicrobial compositions
Assignee: Procter and Gamble Co
•
Filing: 1995-10-16
•
Granted: 1997-11-11
•
Expires: 2015-10-16
Abstract
Abstract The present invention relates to improved topical pharmaceutical compositions having improved aesthetics which are useful for imparting antimicrobial actives. In particular, it relates to topical moisturizing compositions containing one or more antimicrobial active compounds. These compositions are also useful for providing relief from symptoms associated with, for example, vaginal yeast infections.
Inventors
- 👤 Sekhar Mitra
- 👤 George Endel Deckner
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 09:52
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0034; A61K31/00; A61K31/33; A61K31/395; A61K31/41; A61K31/4164; A61K31/4174
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
129 words
A pharmaceutical composition for moisturizing membranous tissue and treating infections comprising: (a) from about 0.01% to about 4% of clotrimazole; (b) from about 1% to about 10% of a moisturizing component selected from the group consisting of C 3 -C 6 diols and triols, urea, guanidine, elycolic acid and glycolate salts, lactic acid and lactate salts, polyhydroxy alcohols, polyethylene glycol, sugar and starches, sugar and starch derivatives, D-panthenol, hyaluronic acid, lactamide, monoethanolamine, acetamide monoethanolamine, and mixtures thereof; and (c) a pharmaceutically-acceptable aqueous gel carrier consisting essentially of from about 0.05% to about 1% of a water-soluble, nonionic polyacrylamide gelling agent comprising monomers selected from the group consisting of acrylamide and methacrylamides wherein said composition has a viscosity of from about 40,000 about 100,000 cps (20° C., heat Brookfield RVT).
Claim 2
Dependent Claim
129 words
A pharmaceutical composition for moisturizing membranous tissue and treating infections comprising: (a) from about 0.01% to about 4% of clotrimazole; (b) from about 1% to about 10% of a moisturizing component selected from the group consisting of C 3 -C 6 diols and triols, urea, guanidine, elycolic acid and glycolate salts, lactic acid and lactate salts, polyhydroxy alcohols, polyethylene glycol, sugar and starches, sugar and starch derivatives, D-panthenol, hyaluronic acid, lactamide, monoethanolamine, acetamide monoethanolamine, and mixtures thereof; and (c) a pharmaceutically-acceptable aqueous gel carrier consisting essentially of from about 0.05% to about 1% of a water-soluble, nonionic polyacrylamide gelling agent comprising monomers selected from the group consisting of acrylamide and methacrylamides wherein said composition has a viscosity of from about 40,000 about 100,000 cps (20° C., heat Brookfield RVT).
Claim 3
Dependent Claim
36 words
A pharmaceutical composition according to claim 1 wherein said moisturizing component is selected from the group consisting of the C 3 -C 6 diols and triols; sorbitol; glycerin; hexanetriol, propylene glycol, hexylene glycol and mixtures thereof.
Claim 4
Dependent Claim
31 words
A pharmaceutical composition according to claim 1 wherein said moisturizing component is a polyhydroxy alcohol selected from the group consisting of sorbitol, glycerin, hexanetriol, propylene glycol, hexylene glycol and mixtures thereof.
Claim 5
Dependent Claim
37 words
A pharmaceutical composition according to claim 1 wherein said polyacrylamide comprises monomers selected from acrylamide and methacrylamide which are unsubstituted or substituted with at least one alkyl groups having from about 1 to about 5 carbon atoms.
Claim 6
Dependent Claim
23 words
A pharmaceutical composition according to claim 4 wherein said wherein said composition has a viscosity of from about 40,000 to about 80,000 cps.
Claim 7
Dependent Claim
16 words
A pharmaceutical composition according to claim 5 wherein said composition further comprises an additional pharmaceutical active.
Claim 8
Dependent Claim
30 words
A pharmaceutical composition according to claim 6 wherein said additional pharmaceutical active is selected from the group consisting of vitamins, analgesics, anti-inflammatory agents, antipuritics, antipyretics, anesthetic agents, and mixtures thereof.
Claim 9
Dependent Claim
23 words
A method for treating infections and providing moisturizing by administration of a safe and effective amount of the pharmaceutical composition of claim 1.
Claim 10
Dependent Claim
23 words
A method for treating infections and providing moisturizing by administration of a safe and effective amount of the pharmaceutical composition of claim 2.
Claim 11
Dependent Claim
23 words
A method for treating infections and providing moisturizing by administration of a safe and effective amount of the pharmaceutical composition of claim 3.
Claim 12
Dependent Claim
23 words
A method for treating infections and providing moisturizing by administration of a safe and effective amount of the pharmaceutical composition of claim 4.
Claim 13
Dependent Claim
30 words
A method for the prophylactic treatment of membranous tissue infections by prophylactic administration of a safe and effective amount of the pharmaceutical composition of claim 1 to said membranous tissue.
Claim 14
Dependent Claim
30 words
A method for the prophylactic treatment of membranous tissue infections by prophylactic administration of a safe and effective amount of the pharmaceutical composition of claim 3 to said membranous tissue.
Claim 15
Dependent Claim
30 words
A method for the prophylactic treatment of membranous tissue infections by prophylactic administration of a safe and effective amount of the pharmaceutical composition of claim 4 to said membranous tissue.
Claim 16
Dependent Claim
12 words
A method according to claim 12 wherein said membranous tissue is vaginal.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2000-11-10 | 2001-05-12 | 2001-11-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-11-10 | 2005-05-12 | 2005-11-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-11-10 | 2009-05-12 | 2009-11-11 | $7700.00 | Window Closed / Lapsed |