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US5656475A
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Use of lymphocytes transformed with herpesvirus saimiri in a process for replicating viruses of the HIV type which cause immune deficiency
Assignee: Siemens Healthcare Diagnostics GmbH Germany
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Filing: 1994-03-10
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Granted: 1997-08-12
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Expires: 2014-03-10
Abstract
Abstract A process is disclosed for replicating viruses of the HIV type which cause immune deficiency, in which process lymphocytes are employed which have been transformed with herpesvirus saimiri.
Inventors
- 👤 Sigrid Nick
- 👤 Helmut Fickenscher
- 👤 Brigitte Biesinger-Zwosta
- 👤 Gerhard Jahn
- 👤 Bernhard Fleckenstein
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 21:11
CPC Classifications
C; C12; C12N; C12N7/00; C12N2710/00; C12N2710/00011; C12N2710/16011; C12N2710/16611
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
30 words
A process for replicating viruses of the HIV type which cause immune deficiency, wherein the viruses are replicated with the aid of lymphocytes which have been transformed with herpesvirus saimiri.
Claim 2
Dependent Claim
30 words
A process for replicating viruses of the HIV type which cause immune deficiency, wherein the viruses are replicated with the aid of lymphocytes which have been transformed with herpesvirus saimiri.
Claim 3
Dependent Claim
26 words
The process as claimed in claim 1, wherein the human lymphocytes are transformed with herpesvirus saimiri, herpesvirus of group C or of group Non A-Non B.
Claim 4
Dependent Claim
12 words
The process as claimed in claim 1, wherein the lymphocytes are CD-4-positive.
Claim 5
Dependent Claim
27 words
The process as claimed in claim 1, wherein the human lymphocytes originate from thymus, peripheral blood, umbilical cord blood, lymph nodes, lymphatic vessels, spleen or bone marrow.
Claim 6
Dependent Claim
27 words
The process as claimed in claim 4, wherein the lymphocytes transformed with herpesvirus saimiri are selected from the cell lines CB-15, CB-23, PB-W, PB-M, Lucas and Kesting.
Claim 7
Dependent Claim
26 words
The process as claimed in claim 1, wherein the viruses of the HIV type which cause immune deficiency are those which originate from asymptomatic, seropositive patients.
Claim 8
Dependent Claim
18 words
The process as claimed in claim 1, wherein lymphocytes transformed with herpesvirus saimiri are co-cultivated with other cells.
References Cited (Backward Citations)
WO1990004020A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2000-08-11 | 2001-02-10 | 2001-08-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-08-11 | 2005-02-10 | 2005-08-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-08-11 | 2009-02-10 | 2009-08-12 | $7700.00 | Window Closed / Lapsed |