US5609157A
Expired / Lapsed
US
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Systems and methods for analyzing biopotential morphologies in body tissue using iterative techniques
Assignee: EP Technologies Inc
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Filing: 1995-02-17
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Granted: 1997-03-11
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Expires: 2015-02-17
Abstract
Abstract Systems and methods analyze biopotential morphologies in myocardial tissue by comparing a template of a cardiac event of known diagnosis to one or more samples of a paced cardiac event. The systems and methods generate an output based upon the comparison. The comparison yields an output, which indicates how alike the input sample is to the input template. The output can be used by the physician, for example, to aid in the location of sites that are potentially appropriate for ablation. The systems and methods employing different pacing and/or comparative techniques to provide multiple outputs. The pacing techniques that the systems and methods employ can comprise entrainment pacing or pace mapping. Various alternative comparison techniques include matched filtering, cross correlation, norm of the difference, and symmetry matching.
Inventors
- 👤 Dorin Panescu
- 👤 James G. Whayne
- 👤 David K. Swanson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 22:17
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/40; A61N1/403; A61B; A61B5/00; A61B5/24; A61B5/25; A61B5/279; A61B5/28; A61B5/283; A61B5/287; A61B5/316; A61B5/318; A61B5/346; A61B5/349; A61B5/35; A61B5/68; A61B5/6846; A61B5/6847; A61B5/6852; A61B5/6855; A61B5/6858; A61N1/02; A61N1/04; A61N1/05; A61N1/056; A61B1/00; A61B1/005; A61B1/0051
Claims Analysis
Total Claims: 86
Claim 1
Independent Claim
110 words
A processing element for analyzing biopotential morphologies in myocardial tissue comprising first means for inputting a template of a cardiac event of known diagnosis in a region of myocardial tissue, second means for inputting a first sample of paced biopotentials occurring in the tissue region as a result of pacing using a first technique, third means for inputting a second sample of paced biopotentials occurring in the tissue region as a result of pacing using a second technique different than the first technique, and fourth means for electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 2
Dependent Claim
110 words
A processing element for analyzing biopotential morphologies in myocardial tissue comprising first means for inputting a template of a cardiac event of known diagnosis in a region of myocardial tissue, second means for inputting a first sample of paced biopotentials occurring in the tissue region as a result of pacing using a first technique, third means for inputting a second sample of paced biopotentials occurring in the tissue region as a result of pacing using a second technique different than the first technique, and fourth means for electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 3
Dependent Claim
141 words
A processing element for analyzing biopotential morphologies in myocardial tissue comprising first means for inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, second means for inputting a first sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a first technique, third means for inputting a second sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a second technique different than the first technique, and fourth means for electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 4
Dependent Claim
141 words
A processing element for analyzing biopotential morphologies in myocardial tissue comprising first means for inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, second means for inputting a first sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a first technique, third means for inputting a second sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a second technique different than the first technique, and fourth means for electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 5
Dependent Claim
153 words
A processing element for analyzing biopotential morphologies in myocardial tissue comprising first means for inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, second means for inputting a first sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a first technique, third means for inputting a second sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a second technique different than the first technique, one of the first and second techniques comprising entrainment or reset pacing, and fourth means for electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 6
Dependent Claim
153 words
A processing element for analyzing biopotential morphologies in myocardial tissue comprising first means for inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, second means for inputting a first sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a first technique, third means for inputting a second sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a second technique different than the first technique, one of the first and second techniques comprising entrainment or reset pacing, and fourth means for electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 7
Dependent Claim
166 words
A processing element for analyzing biopotential morphologies in myocardial tissue comprising first means for inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, second means for inputting a first sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a first technique, third means for inputting a second sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a second technique different than the first technique, one of the first and second techniques comprising entrainment or reset pacing and the other one of the first and second techniques comprising pace mapping, and fourth means for electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 8
Dependent Claim
166 words
A processing element for analyzing biopotential morphologies in myocardial tissue comprising first means for inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, second means for inputting a first sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a first technique, third means for inputting a second sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a second technique different than the first technique, one of the first and second techniques comprising entrainment or reset pacing and the other one of the first and second techniques comprising pace mapping, and fourth means for electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 9
Dependent Claim
33 words
An element according to claim 1 or 2 or 3 or 4 wherein at least one of the outputs comprises a matching coefficient indicating how alike the respective sample is to the template.
Claim 10
Dependent Claim
29 words
An element according to claim 1 or 2 or 3 or 4 wherein the fourth means compares at least one of the samples to the template by matched filtering.
Claim 11
Dependent Claim
29 words
An element according to claim 1 or 2 or 3 or 4 wherein the fourth means compares at least one of the samples to the template by cross correlation.
Claim 12
Dependent Claim
33 words
An element according to claim 1 or 2 or 3 or 4 wherein the fourth means compares at least one of the samples to the template by deriving a norm of the difference.
Claim 13
Dependent Claim
46 words
An element according to claim 1 or 2 or 3 or 4 wherein the fourth means compares at least one of the samples to the template by using the template to create a matched filtered sample and by analyzing the symmetry of the matched filtered sample.
Claim 14
Dependent Claim
57 words
An element according to claim 1 or 2 or 3 or 4 wherein the fourth means compares one of the samples to the template using a first prescribed methodology to generate the first output and compares the other sample to the template using a second prescribed methodology different than the first methodology to generate the second output.
Claim 15
Dependent Claim
18 words
An element according to claim 10 and further including fifth means for comparing the first and second outputs.
Claim 16
Dependent Claim
24 words
An element according to claim 1 or 2 or 3 or 4 and further including fifth means for comparing the first and second outputs.
Claim 17
Independent Claim
191 words
A system for analyzing biopotential morphologies in myocardial tissue comprising electrode means for sensing biopotentials in myocardial tissue, and a processing element coupled to the electrode means comprising first means for conditioning the electrode means to sense a sample of the biopotentials occurring in the tissue region during a cardiac event of known diagnosis and for creating a template based upon the sensed biopotential sample, second means operative in a first mode for conditioning the electrode means to pace using a first technique and to sense using the electrode means a first sample of the paced biopotentials occurring in the tissue region as a result of the first pacing technique, the second means being further selectively operative in a second mode for conditioning the electrode means to pace using a second technique different than the first technique and to sense using the electrode means a second sample of the paced biopotentials occurring in the tissue region as a result of the second pacing technique, and third means for electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 18
Independent Claim
191 words
A system for analyzing biopotential morphologies in myocardial tissue comprising electrode means for sensing biopotentials in myocardial tissue, and a processing element coupled to the electrode means comprising first means for conditioning the electrode means to sense a sample of the biopotentials occurring in the tissue region during a cardiac event of known diagnosis and for creating a template based upon the sensed biopotential sample, second means operative in a first mode for conditioning the electrode means to pace using a first technique and to sense using the electrode means a first sample of the paced biopotentials occurring in the tissue region as a result of the first pacing technique, the second means being further selectively operative in a second mode for conditioning the electrode means to pace using a second technique different than the first technique and to sense using the electrode means a second sample of the paced biopotentials occurring in the tissue region as a result of the second pacing technique, and third means for electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 19
Dependent Claim
24 words
A system according to claim 13 and further including an element supporting the electrode means for operative association with a region of heart tissue.
Claim 20
Dependent Claim
30 words
A system according to claim 13 wherein at least one of the first and second outputs comprises a matching coefficient indicating how alike the respective sample is to the template.
Claim 21
Dependent Claim
23 words
A system according to claim 13 wherein the third means compares at least one of the samples to the template by matched filtering.
Claim 22
Dependent Claim
23 words
A system according to claim 13 wherein the third means compares at least one of the samples to the template by cross correlation.
Claim 23
Dependent Claim
27 words
A system according to claim 13 wherein the third means compares at least one of the samples to the template by deriving a norm of the difference.
Claim 24
Dependent Claim
40 words
A system according to claim 13 wherein the third means compares at least one of the samples to the template by using the template to create a matched filtered sample and by analyzing the symmetry of the matched filtered sample.
Claim 25
Dependent Claim
51 words
A system according to claim 13 wherein the third means compares one of the samples to the template using a first prescribed methodology to generate the first output and compares the other sample to the template using a second prescribed methodology different than the first methodology to generate the second output.
Claim 26
Dependent Claim
20 words
A system according to claim 13 or 20 and further including fourth means for comparing the first and second outputs.
Claim 27
Dependent Claim
19 words
A system according to claim 13 wherein one of the first and second pacing techniques entrainment paces the heart.
Claim 28
Dependent Claim
19 words
A system according to claim 13 wherein one of the first and second pacing techniques pace maps the heart.
Claim 29
Dependent Claim
122 words
An element for analyzing biopotential morphologies in myocardial tissue comprising first means for inputting a template of a cardiac event of known diagnosis in a region of myocardial tissue, second means for inputting a sample of paced biopotentials occurring in the tissue region as a result of a pacing signal, third means operative in a first mode for electronically comparing the sample to the template using a first comparison technique and generating a first output based upon the first comparison technique, the third means being further selectively operative in a second mode for electronically comparing the sample to the template using a second comparison technique different than the first comparison technique and generating a second output based upon the second comparison technique.
Claim 30
Dependent Claim
122 words
An element for analyzing biopotential morphologies in myocardial tissue comprising first means for inputting a template of a cardiac event of known diagnosis in a region of myocardial tissue, second means for inputting a sample of paced biopotentials occurring in the tissue region as a result of a pacing signal, third means operative in a first mode for electronically comparing the sample to the template using a first comparison technique and generating a first output based upon the first comparison technique, the third means being further selectively operative in a second mode for electronically comparing the sample to the template using a second comparison technique different than the first comparison technique and generating a second output based upon the second comparison technique.
Claim 31
Dependent Claim
137 words
An element for analyzing biopotential morphologies in myocardial tissue comprising first means for inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, second means for inputting a sample of a paced electrogram having a duration not shorter than the template recorded in the tissue region, third means operative in a first mode for electronically comparing the sample to the template using a first comparison technique and generating a first output based upon the first comparison technique, the third means being further selectively operative in a second mode for electronically comparing the sample to the template using a second comparison technique different than the first comparison technique and generating a second output based upon the second comparison technique.
Claim 32
Dependent Claim
137 words
An element for analyzing biopotential morphologies in myocardial tissue comprising first means for inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, second means for inputting a sample of a paced electrogram having a duration not shorter than the template recorded in the tissue region, third means operative in a first mode for electronically comparing the sample to the template using a first comparison technique and generating a first output based upon the first comparison technique, the third means being further selectively operative in a second mode for electronically comparing the sample to the template using a second comparison technique different than the first comparison technique and generating a second output based upon the second comparison technique.
Claim 33
Dependent Claim
142 words
An element for analyzing biopotential morphologies in myocardial tissue comprising first means for inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, second means for inputting a sample of a paced electrogram having a duration not shorter than the template recorded in the tissue region during entrainment or reset pacing, third means operative in a first mode for electronically comparing the sample to the template using a first comparison technique and generating a first output based upon the first comparison technique, the third means being further selectively operative in a second mode for electronically comparing the sample to the template using a second comparison technique different than the first comparison technique and generating a second output based upon the second comparison technique.
Claim 34
Dependent Claim
142 words
An element for analyzing biopotential morphologies in myocardial tissue comprising first means for inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, second means for inputting a sample of a paced electrogram having a duration not shorter than the template recorded in the tissue region during entrainment or reset pacing, third means operative in a first mode for electronically comparing the sample to the template using a first comparison technique and generating a first output based upon the first comparison technique, the third means being further selectively operative in a second mode for electronically comparing the sample to the template using a second comparison technique different than the first comparison technique and generating a second output based upon the second comparison technique.
Claim 35
Dependent Claim
31 words
An element according to claim 24 or 25 or 26 wherein at least one of the outputs comprises a matching coefficient indicating how alike the respective sample is to the template.
Claim 36
Dependent Claim
26 words
An element according to claim 24 or 25 or 26 wherein one of the comparison techniques compares the respective sample to the template by matched filtering.
Claim 37
Dependent Claim
26 words
An element according to claim 24 or 25 or 26 wherein one of the comparison techniques compares the respective sample to the template by cross correlation.
Claim 38
Dependent Claim
30 words
An element according to claim 24 or 25 or 26 wherein one of the comparison techniques compares the respective sample to the template by deriving a norm of the difference.
Claim 39
Dependent Claim
43 words
An element according to claim 24 or 25 or 26 wherein one of the comparison techniques compares the respective sample to the template by using the template to create a matched filtered sample and by analyzing the symmetry of the matched filtered sample.
Claim 40
Dependent Claim
22 words
An element according to claim 24 or 25 or 26 and further including fourth means for comparing the first and second outputs.
Claim 41
Independent Claim
180 words
A system for analyzing biopotential morphologies in myocardial tissue comprising electrode means for sensing biopotentials in myocardial tissue, and a processing element coupled to the electrode means comprising first means for conditioning the electrode means to sense a sample of the biopotentials occurring in the tissue region during a cardiac event of known diagnosis and for creating a template based upon the sensed biopotential sample, second means operative for conditioning the electrode means to emit a pacing signal and to sense using the electrode means a sample of the paced biopotentials occurring in the tissue region as a result of the pacing signal, and <third means operative in a first mode for electronically comparing the paced biopotential sample to the template using a first comparison technique and generating a first output based upon the first comparison technique, the third means being further selectively operative in a second mode for electronically comparing the paced biopotential sample to the template using a second comparison technique different than the first comparison technique and generating a second output based upon the second comparison technique.
Claim 42
Independent Claim
180 words
A system for analyzing biopotential morphologies in myocardial tissue comprising electrode means for sensing biopotentials in myocardial tissue, and a processing element coupled to the electrode means comprising first means for conditioning the electrode means to sense a sample of the biopotentials occurring in the tissue region during a cardiac event of known diagnosis and for creating a template based upon the sensed biopotential sample, second means operative for conditioning the electrode means to emit a pacing signal and to sense using the electrode means a sample of the paced biopotentials occurring in the tissue region as a result of the pacing signal, and <third means operative in a first mode for electronically comparing the paced biopotential sample to the template using a first comparison technique and generating a first output based upon the first comparison technique, the third means being further selectively operative in a second mode for electronically comparing the paced biopotential sample to the template using a second comparison technique different than the first comparison technique and generating a second output based upon the second comparison technique.
Claim 43
Dependent Claim
24 words
A system according to claim 33 and further including an element supporting the electrode means for operative association with a region of heart tissue.
Claim 44
Dependent Claim
30 words
A system according to claim 33 wherein at least one of the first and second outputs comprises a matching coefficient indicating how alike the respective sample is to the template.
Claim 45
Dependent Claim
22 words
A system according to claim 33 wherein one of the comparison techniques compares the respective sample to the template by matched filtering.
Claim 46
Dependent Claim
22 words
A system according to claim 33 wherein one of the comparison techniques compares the respective sample to the template by cross correlation.
Claim 47
Dependent Claim
26 words
A system according to claim 33 wherein one of the comparison techniques compares the respective sample to the template by deriving a norm of the difference.
Claim 48
Dependent Claim
39 words
A system according to claim 33 wherein one of the comparison techniques compares the respective sample to the template by using the template to create a matched filtered sample and by analyzing the symmetry of the matched filtered sample.
Claim 49
Dependent Claim
18 words
A system according to claim 33 and further including fourth means for comparing the first and second outputs.
Claim 50
Independent Claim
266 words
A system for analyzing biopotential morphologies in myocardial tissue comprising electrode means for sensing biopotentials in myocardial tissue, and a processing element coupled to the electrode means comprising first means for conditioning the electrode means to sense a sample of the biopotentials occurring in the tissue region during a cardiac event of known diagnosis and for creating a template based upon the sensed biopotential sample, second means operative in a first pacing mode for conditioning the electrode means to pace using a first technique and to sense using the electrode means a first sample of the paced biopotentials occurring in the tissue region as a result of the first pacing technique, the second means being further selectively operative in a second pacing mode for conditioning the electrode means to pace using a second technique different than the first pacing technique and to sense using the electrode means a second sample of the paced biopotentials occurring in the tissue region as a result of the second pacing technique, and third means operative in a first comparison mode for electronically comparing each of the first and second paced biopotential samples individually to the template using a first comparison technique and generating first and second outputs based upon each comparison using the first comparison technique, the third means being further selectively operative in a second comparison mode for electronically comparing each of the first and second paced biopotential samples individually to the template using a second comparison technique different than the first comparison technique and generating third and fourth outputs based upon each comparison using the second comparison technique.
Claim 51
Independent Claim
266 words
A system for analyzing biopotential morphologies in myocardial tissue comprising electrode means for sensing biopotentials in myocardial tissue, and a processing element coupled to the electrode means comprising first means for conditioning the electrode means to sense a sample of the biopotentials occurring in the tissue region during a cardiac event of known diagnosis and for creating a template based upon the sensed biopotential sample, second means operative in a first pacing mode for conditioning the electrode means to pace using a first technique and to sense using the electrode means a first sample of the paced biopotentials occurring in the tissue region as a result of the first pacing technique, the second means being further selectively operative in a second pacing mode for conditioning the electrode means to pace using a second technique different than the first pacing technique and to sense using the electrode means a second sample of the paced biopotentials occurring in the tissue region as a result of the second pacing technique, and third means operative in a first comparison mode for electronically comparing each of the first and second paced biopotential samples individually to the template using a first comparison technique and generating first and second outputs based upon each comparison using the first comparison technique, the third means being further selectively operative in a second comparison mode for electronically comparing each of the first and second paced biopotential samples individually to the template using a second comparison technique different than the first comparison technique and generating third and fourth outputs based upon each comparison using the second comparison technique.
Claim 52
Dependent Claim
24 words
A system according to claim 41 and further including an element supporting the electrode means for operative association with a region of heart tissue.
Claim 53
Dependent Claim
35 words
A system according to claim 41 wherein the first, second, third, and fourth outputs comprise, respectively, first, second, third, and fourth matching coefficients indicating how alike the respective paced biopotential sample is to the template.
Claim 54
Dependent Claim
22 words
A system according to claim 41 wherein one of the comparison techniques compares the respective sample to the template by matched filtering.
Claim 55
Dependent Claim
22 words
A system according to claim 41 wherein one of the comparison techniques compares the respective sample to the template by cross correlation.
Claim 56
Dependent Claim
26 words
A system according to claim 41 wherein one of the comparison techniques compares the respective sample to the template by deriving a norm of the difference.
Claim 57
Dependent Claim
39 words
A system according to claim 41 wherein one of the comparison techniques compares the respective sample to the template by using the template to create a matched filtered sample and by analyzing the symmetry of the matched filtered sample.
Claim 58
Dependent Claim
19 words
A system according to claim 41 wherein one of the first and second pacing techniques entrainment paces the heart.
Claim 59
Dependent Claim
19 words
A system according to claim 41 wherein one of the first and second pacing techniques pace maps the heart.
Claim 60
Independent Claim
99 words
A method for analyzing biopotential morphologies in myocardial tissue comprising the steps of inputting a template of a cardiac event of known diagnosis in a region of myocardial tissue, inputting a first sample of paced biopotentials occurring in the tissue region as a result of pacing using a first technique, a second sample of paced biopotentials occurring in the tissue region as a result of pacing using a second technique different than the first technique, and electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 61
Independent Claim
99 words
A method for analyzing biopotential morphologies in myocardial tissue comprising the steps of inputting a template of a cardiac event of known diagnosis in a region of myocardial tissue, inputting a first sample of paced biopotentials occurring in the tissue region as a result of pacing using a first technique, a second sample of paced biopotentials occurring in the tissue region as a result of pacing using a second technique different than the first technique, and electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 62
Independent Claim
131 words
A method for analyzing biopotential morphologies in myocardial tissue comprising the steps of inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, inputting a first sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a first technique, inputting a second sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a second technique different than the first technique, and electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 63
Independent Claim
131 words
A method for analyzing biopotential morphologies in myocardial tissue comprising the steps of inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, inputting a first sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a first technique, inputting a second sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a second technique different than the first technique, and electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 64
Independent Claim
145 words
A method for analyzing biopotential morphologies in myocardial tissue comprising the steps of inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, inputting a first sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a first technique, inputting a second sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a second technique different than the first technique, one of the first and second pacing signals techniques comprising entrainment or reset pacing, and electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 65
Independent Claim
145 words
A method for analyzing biopotential morphologies in myocardial tissue comprising the steps of inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, inputting a first sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a first technique, inputting a second sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a second technique different than the first technique, one of the first and second pacing signals techniques comprising entrainment or reset pacing, and electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 66
Independent Claim
158 words
A method for analyzing biopotential morphologies in myocardial tissue comprising the steps of inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, inputting a first sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a first technique, inputting a second sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a second technique different than the first technique, one of the first and second pacing techniques comprising entrainment or reset pacing and the other one of the first and second pacing techniques comprising pace mapping, and electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 67
Independent Claim
158 words
A method for analyzing biopotential morphologies in myocardial tissue comprising the steps of inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, inputting a first sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a first technique, inputting a second sample comprising a paced electrogram having a duration not shorter than the template recorded in the tissue region as a result of pacing using a second technique different than the first technique, one of the first and second pacing techniques comprising entrainment or reset pacing and the other one of the first and second pacing techniques comprising pace mapping, and electronically comparing each of the first and second samples individually to the template and generating first and second outputs based upon each comparison.
Claim 68
Dependent Claim
33 words
A method according to claim 50 or 51 or 52 or 53 wherein at least one of the outputs comprises a matching coefficient indicating how alike the respective sample is to the template.
Claim 69
Dependent Claim
29 words
A method according to claim 50 or 51 or 52 or 53 wherein the comparing step compares at least one of the samples to the template by matched filtering.
Claim 70
Dependent Claim
29 words
A method according to claim 50 or 51 or 52 or 53 wherein the comparing step compares at least one of the samples to the template by cross correlation.
Claim 71
Dependent Claim
33 words
A method according to claim 50 or 51 or 52 or 53 wherein the comparing step compares at least one of the samples to the template by deriving a norm of the difference.
Claim 72
Dependent Claim
46 words
A method according to claim 50 or 51 or 52 or 53 wherein the comparing step compares at least one of the samples to the template by using the template to create a matched filtered sample and by analyzing the symmetry of the matched filtered sample.
Claim 73
Dependent Claim
57 words
A method according to claim 50 or 51 or 52 or 53 wherein the comparing step compares one of the samples to the template using a first prescribed methodology to generate the first output and compares the other sample to the template using a second prescribed methodology different than the first methodology to generate the second output.
Claim 74
Dependent Claim
24 words
A method according to claim 50 or 51 or 52 or 53 and further including the step of comparing the first and second outputs.
Claim 75
Independent Claim
100 words
A method for analyzing biopotential morphologies in myocardial tissue comprising the steps of inputting a template of a cardiac event of known diagnosis in a region of myocardial tissue, inputting a sample of paced biopotentials occurring in the tissue region as a result of a pacing signal, electronically comparing the sample to the template using a first comparison technique and generating a first output based upon the first comparison technique, and electronically comparing the sample to the template using a second comparison technique different than the first comparison technique and generating a second output based upon the second comparison technique.
Claim 76
Independent Claim
100 words
A method for analyzing biopotential morphologies in myocardial tissue comprising the steps of inputting a template of a cardiac event of known diagnosis in a region of myocardial tissue, inputting a sample of paced biopotentials occurring in the tissue region as a result of a pacing signal, electronically comparing the sample to the template using a first comparison technique and generating a first output based upon the first comparison technique, and electronically comparing the sample to the template using a second comparison technique different than the first comparison technique and generating a second output based upon the second comparison technique.
Claim 77
Independent Claim
115 words
A method for analyzing biopotential morphologies in myocardial tissue comprising the steps of inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, inputting a sample of a paced electrogram having a duration not shorter than the template recorded in the tissue region, electronically comparing the sample to the template using a first comparison technique and generating a first output based upon the first comparison technique, and electronically comparing the sample to the template using a second comparison technique different than the first comparison technique and generating a second output based upon the second comparison technique.
Claim 78
Independent Claim
115 words
A method for analyzing biopotential morphologies in myocardial tissue comprising the steps of inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, inputting a sample of a paced electrogram having a duration not shorter than the template recorded in the tissue region, electronically comparing the sample to the template using a first comparison technique and generating a first output based upon the first comparison technique, and electronically comparing the sample to the template using a second comparison technique different than the first comparison technique and generating a second output based upon the second comparison technique.
Claim 79
Independent Claim
120 words
A method for analyzing biopotential morphologies in myocardial tissue comprising the steps of inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, inputting a sample of a paced electrogram having a duration not shorter than the template recorded in the tissue region during entrainment or reset pacing, electronically comparing the sample to the template using a first comparison technique and generating a first output based upon the first comparison technique, and electronically comparing the sample to the template using a second comparison technique different than the first comparison technique and generating a second output based upon the second comparison technique.
Claim 80
Independent Claim
120 words
A method for analyzing biopotential morphologies in myocardial tissue comprising the steps of inputting a template of an electrogram having a duration not greater than one heart beat recorded during a cardiac event of known diagnosis in a region of myocardial tissue, inputting a sample of a paced electrogram having a duration not shorter than the template recorded in the tissue region during entrainment or reset pacing, electronically comparing the sample to the template using a first comparison technique and generating a first output based upon the first comparison technique, and electronically comparing the sample to the template using a second comparison technique different than the first comparison technique and generating a second output based upon the second comparison technique.
Claim 81
Dependent Claim
31 words
A method according to claim 61 or 62 or 63 wherein at least one of the outputs comprises a matching coefficient indicating how alike the respective sample is to the template.
Claim 82
Dependent Claim
26 words
A method according to claim 61 or 62 or 63 wherein one of the comparison techniques compares the respective sample to the template by matched filtering.
Claim 83
Dependent Claim
26 words
A method according to claim 61 or 62 or 63 wherein one of the comparison techniques compares the respective sample to the template by cross correlation.
Claim 84
Dependent Claim
30 words
A method according to claim 61 or 62 or 63 wherein one of the comparison techniques compares the respective sample to the template by deriving a norm of the difference.
Claim 85
Dependent Claim
43 words
A method according to claim 61 or 62 or 63 wherein one of the comparison techniques compares the respective sample to the template by using the template to create a matched filtered sample and by analyzing the symmetry of the matched filtered sample.
Claim 86
Dependent Claim
22 words
A method according to claim 61 or 62 or 63 and further including the step of comparing the first and second outputs.
References Cited (Backward Citations)
US4105023A
Cited
US4149527A
Cited
US4244376A
Cited
US4868773A
Cited
US4674509A
Cited
US4723553A
Cited
US5029118A
Cited
US4793361A
Cited
US5010888A
Cited
US5436564A
Cited
US5238000A
Cited
US5168459A
Cited
US5415166A
Cited
US5267567A
Cited
US5323781A
Cited
US5273049A
Cited
US5311874A
Cited
US5324284A
Cited
US5411025A
Cited
US5311873A
Cited
US5450846A
Cited
WO1994016619A1
Cited
WO1994021165A1
Cited
US5476495A
Cited
WO1994021168A1
Cited
US5391199A
Cited
US5409000A
Cited
US5409007A
Cited
US5454370A
Cited
US5405375A
Cited
US5487391A
Cited
US5485849A
Cited
US5447519A
Cited
US5413105A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2000-03-10 | 2000-09-09 | 2001-03-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-03-10 | 2004-09-09 | 2005-03-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-03-10 | 2008-09-09 | 2009-03-11 | $7700.00 | Window Closed / Lapsed |