US5311873A
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Comparative analysis of body surface potential distribution during cardiac pacing
Assignee: Polytechnique Montréal
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Filing: 1992-08-28
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Granted: 1994-05-17
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Expires: 2012-08-28
Abstract
Abstract Body surface potential map (BSPM) pace-mapping is a system and method that can be used in medicine to localize with precision the site of origin of abnormal cardiac electrical activity and to guide the positioning of a catheter over this site of origin, such as the site of ventricular preexcitation in patients with the Wolff-Parkinson-White syndrome or the focus of ectopic activity in patients with tachycardia. Body surface potential distributions are measured with a large number of electrodes, e.g. 24 to 128, distributed over the entire torso surface. The electrical signals are first amplified, converted into digital data and treated to remove electrical or muscle artifacts. Data recorded during abnormal activation (reference beat) are aligned with data recorded during cardiac pacing (paced beat) so as to maximize the average value of the correlation coefficient between the reference and the paced potential distributions during a preset time interval following the beginning of the QRS complex. Reference and paced maps showing color-coded isopotential contour lines are displayed side by side for the same time instant. Visual analysis of these maps according to previously published criteria determines the relative position of the pacing catheter with respect to the focus of abnormal activation, and gives information so as to guide the catheter toward the focus.
Inventors
- 👤 Pierre Savard
- 👤 Reginald Nadeau
- 👤 Marc Dubuc
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 13:17
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/18; A61N1/32; A61N1/36; A61N1/372; A61B; A61B34/00; A61B34/20; A61B2034/2046; A61B2034/2051; A61B2034/2053
Claims Analysis
Total Claims: 22
Claim 1
Independent Claim
193 words
A method of locating a position of interest in the heart of a patient and in positioning a surgical instrument at this position, comprising the steps of: A. placing a plurality of electrodes on the surface of said patient in the area of the torso of the patient; B. obtaining readouts from said electrodes during a pre-excitation phase or at the onset of an abnormal beat and forming therefrom a first body surface potential map (BSPM); C. estimating said position of interest from said first BSPM; D. placing said surgical instrument at said estimated position; E. pacing the heart of said patient with an electrical signal applied through said surgical instrument; F. obtaining readouts from said electrodes during said paced phase and forming a further BSPM therefrom; G. determining from said further BSPM, when compared with the first BSPM, if the surgical instrument is in the correct position; H. if the instrument is not in the correct position, moving the instrument in a direction as indicated by the comparison of the further BSPM with the first BSPM; I. repeating steps E. to G. until the surgical instrument is at the position of interest.
Claim 2
Independent Claim
193 words
A method of locating a position of interest in the heart of a patient and in positioning a surgical instrument at this position, comprising the steps of: A. placing a plurality of electrodes on the surface of said patient in the area of the torso of the patient; B. obtaining readouts from said electrodes during a pre-excitation phase or at the onset of an abnormal beat and forming therefrom a first body surface potential map (BSPM); C. estimating said position of interest from said first BSPM; D. placing said surgical instrument at said estimated position; E. pacing the heart of said patient with an electrical signal applied through said surgical instrument; F. obtaining readouts from said electrodes during said paced phase and forming a further BSPM therefrom; G. determining from said further BSPM, when compared with the first BSPM, if the surgical instrument is in the correct position; H. if the instrument is not in the correct position, moving the instrument in a direction as indicated by the comparison of the further BSPM with the first BSPM; I. repeating steps E. to G. until the surgical instrument is at the position of interest.
Claim 3
Dependent Claim
37 words
A method as defined in claim 1 wherein said first BSPM is obtained during the delta wave for a sinus rhythm beat in WPW patients or at the beginning of the QRS in patients with ventricular tachycardia.
Claim 4
Dependent Claim
25 words
A method as defined in claim 1 wherein said instrument is a catheter and said catheter is inserted into the ventricles of said patient's heart.
Claim 5
Dependent Claim
16 words
A method as defined in claim 1 wherein said BSPM's are displayed on a CRT terminal.
Claim 6
Dependent Claim
37 words
A method as defined in claim 4 and including the further step of selecting one of said electrodes to provide a reference signal to permit the manual selection of a window containing the beat to be analyzed.
Claim 7
Dependent Claim
42 words
A method as defined in claim 1 and including a preliminary step, carried out before step A, of automatically identifying and correcting faulty leads, that is, leads which carry signals which are saturated as well as signals contaminated by excessive electrical noise.
Claim 8
Dependent Claim
25 words
A method as defined in claim 6 wherein said preliminary step includes interpolating signals from valid leads near leads which have been identified as faulty.
Claim 9
Dependent Claim
48 words
A method as defined in claim 1 wherein, in steps A and F, the onset of a QRS complex is automatically detected and the value of the potential at the QRS onset is subtracted from the read-outs of all leads so as to correct for any baseline shifts.
Claim 10
Dependent Claim
31 words
A method as defined in claim 1 wherein the determination as recited in step G is obtained by as formed in step B and the BSPM as formed in step F.
Claim 11
Dependent Claim
40 words
A method as defined in claim 9 wherein the data of the read-outs obtained in step B are aligned with the data of the read-outs obtained in step F so as to maximize the average value of said correlation coefficient.
Claim 12
Dependent Claim
29 words
A method as defined in claim 10 wherein said data is aligned by analyzing the correlation coefficient during a preset time interval following the beginning of the QRS complex.
Claim 13
Dependent Claim
52 words
A method as defined in claim 11 wherein said BSPMs are displayed on a CRT; and including the further step of displaying the BSPM formed in step B during said preset time interval alongside of the BSPM formed in step F during said preset time interval on said CRT for visual comparison.
Claim 14
Dependent Claim
52 words
A method as defined in claim 12 wherein said BSPMs comprise isopotential lines including a zero isopotential line, a maximum potential marker and a minimum potential marker; and including the further step of displaying only the zero isopotential line and the locations of the maximum and minimum potential values for said BSPMs.
Claim 15
Dependent Claim
26 words
A method as defined in claim 13 and including the step of providing a plot of correlation coefficients for predetremined instances during said preset time interval.
Claim 16
Dependent Claim
82 words
A method as defined in claim 6 and including the step of selecting a dynamic range of value for the read-outs obtained from said electrodes; determining the number of time instances at which each read-out exceeds a preset percentage of this dynamic range; determining if this number of instances corresponds to a consecutive duration greater than a preset duration; and if said read-out from an electrode exceeds the preset duration, considering that the output of this read-out of this electrode is faulty.
Claim 17
Dependent Claim
20 words
A method as defined in claim 15 wherein the preset percentage is 95% and the preset duration is 50 msec.
Claim 18
Dependent Claim
59 words
A method as defined in claim 6 and including filtering the read-out of each electrode with a numerical high-pass filter with a cut-off frequency of 50 Hertz and determining if the total power of the filtered signal exceeds a preset threshold; and if the filtered signal exceeds the preset threshold, considering the read-out of said electrode to be faulty.
Claim 19
Dependent Claim
26 words
A method as defined in claim 7 wherein the interpolation is performed by using read-outs of neighboring leads within a preset radius around the faulty lead.
Claim 20
Dependent Claim
17 words
A method as defined in claim 17 wherein said preset radius is twice the distance between electrodes.
Claim 21
Dependent Claim
31 words
A method as defined in claim 1 wherein said plurality of electrodes comprises between 24 and 128 electrodes; said electrodes being distributed over the front, sides and back of the torso.
Claim 22
Dependent Claim
23 words
A method as defined in claim 20 wherein said read-outs from said electrodes are amplified, filtered, digitized and stored on a magnetic disc.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1997-05-16 | 1997-11-15 | 1998-05-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-05-16 | 2001-11-15 | 2002-05-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-05-16 | 2005-11-15 | 2006-05-17 | $7700.00 | Window Closed / Lapsed |