Patent US5594637A successfully refreshed from Google Patents.
US5594637A
Expired / Lapsed
US
⏱️ 0.0 years remaining
System and method for assessing medical risk
Assignee: Base Ten Systems Inc
•
Filing: 1993-05-26
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Granted: 1997-01-14
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Expires: 2013-05-26
Abstract
Abstract A system and method for assessing the medical risk of a given outcome for a patient comprises obtaining test data from a given patient corresponding to at least one test marker for predicting the medical risk of a given outcome and obtaining at least one variable relating to the given patient and transforming the test data with the variable to produce transformed data for each test markers. A database of transformed data from previously assessed patients is provided and mean and standard deviation values are determined from the database in accordance with the actual occurrence of the given outcome for previously assessed patients. The transformed data is compared with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient and the database is updated with the actual occurrence for the given patient, whereby the determined mean and standard deviation will be adjusted.
Inventors
- 👤 Alan J. Eisenberg
- 👤 Alexander Adelson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 11:11
CPC Classifications
G; G16; G16H; G16H10/00; G16H10/60; G16H15/00; G16H50/00; G16H50/30; G16H50/20
Claims Analysis
Total Claims: 82
Claim 1
Independent Claim
305 words
A system for assessing the medical risk of a given outcome for a patient, the system comprising: data input means receptive of test data from a given patient corresponding to at least one test marker for predicting the medical risk of a given outcome and at least one variable relating to the given patient; means for transforming the test data with the variable to produce transformed data for each test marker; means storing a database of transformed data from other medical risk assessment systems for previously assessed patients; means for determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; means for comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; and means for locally updating the database of said system with the actual occurrence for the given patient; wherein the means for determining mean and standard deviation values includes means for locally adjusting the determined mean and standard deviation values of said system for the locally updated database, whereby the adjusted mean and standard deviation values for said system are adjusted for a particular patient population assessed by said system relative to mean and standard deviation values determined from the database from other medical risk assessment systems; means for storing predetermined requirements for risk data comprising the test data, the said at least one variable, the transformed data, the determined mean and the determined standard deviation; means for validating data when received, transformed and determined with regard to the predetermined requirements comprising means for checking the integrity of the database for each comparison with the data therein and each update of the data therein; and means for indicating when the data does not meet the predetermined requirements.
Claim 2
Independent Claim
305 words
A system for assessing the medical risk of a given outcome for a patient, the system comprising: data input means receptive of test data from a given patient corresponding to at least one test marker for predicting the medical risk of a given outcome and at least one variable relating to the given patient; means for transforming the test data with the variable to produce transformed data for each test marker; means storing a database of transformed data from other medical risk assessment systems for previously assessed patients; means for determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; means for comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; and means for locally updating the database of said system with the actual occurrence for the given patient; wherein the means for determining mean and standard deviation values includes means for locally adjusting the determined mean and standard deviation values of said system for the locally updated database, whereby the adjusted mean and standard deviation values for said system are adjusted for a particular patient population assessed by said system relative to mean and standard deviation values determined from the database from other medical risk assessment systems; means for storing predetermined requirements for risk data comprising the test data, the said at least one variable, the transformed data, the determined mean and the determined standard deviation; means for validating data when received, transformed and determined with regard to the predetermined requirements comprising means for checking the integrity of the database for each comparison with the data therein and each update of the data therein; and means for indicating when the data does not meet the predetermined requirements.
Claim 3
Dependent Claim
26 words
The system according to claim 1, for use in accessing prenatal risks, wherein the test markers include at least one selected from AFP, hCG and uE3.
Claim 4
Dependent Claim
21 words
The system according to claim 2, wherein the variables include at least one selected from age, race, weight and diabetic status.
Claim 5
Dependent Claim
31 words
The system according to claim 1, wherein at least two markers are used and further comprising means for correlating the comparisons of the transformed data for the at least two markers.
Claim 6
Dependent Claim
36 words
The system according to claim 1, further comprising means for storing a plurality of letters, means for selecting a letter based on the transformed data for the given patient and means for printing the selected letter.
Claim 7
Dependent Claim
30 words
The system according to claim 1, wherein the validating means further comprises means for range checking the test markers, the test data and the transformed data for the given patient.
Claim 8
Dependent Claim
27 words
The system according to claim 1, wherein the validating means further comprises means for double copy comparing all data received from and written into the storing means.
Claim 9
Dependent Claim
25 words
The system according to claim 1, wherein the validating means further comprises means for maintaining an archival log of all data changes to the database.
Claim 10
Independent Claim
301 words
A system for assessing the medical risk of a given outcome for a patient, the system comprising: data input means receptive of test data from a given patient corresponding to at least one test marker for predicting the medical risk of a given outcome and at least one variable relating to the given patient; means for transforming the test data with the variable to produce transformed data for each test marker; means storing a database of transformed data from other medical risk assessment systems for previously assessed patients; means for determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; means for comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; and means for locally updating the database of said system with the actual occurrence for the given patient; wherein the means for determining mean and standard deviation values includes means for locally adjusting the determined mean and standard deviation values of said system for the locally updated database, whereby the adjusted mean and standard deviation values for said system are adjusted for a particular patient population assessed by said system relative to mean and standard deviation values determined from the database from other medical risk assessment systems; means for storing predetermined requirements for risk data comprising the test data, the said at least one variable, the transformed data, the determined mean and the determined standard deviation; means for validating data when received, transformed and determined with regard to the predetermined requirements comprising means for range checking the test markers, the test data and the transformed data for the given patient; and means for indicating when the data does not meet the predetermined requirements.
Claim 11
Independent Claim
301 words
A system for assessing the medical risk of a given outcome for a patient, the system comprising: data input means receptive of test data from a given patient corresponding to at least one test marker for predicting the medical risk of a given outcome and at least one variable relating to the given patient; means for transforming the test data with the variable to produce transformed data for each test marker; means storing a database of transformed data from other medical risk assessment systems for previously assessed patients; means for determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; means for comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; and means for locally updating the database of said system with the actual occurrence for the given patient; wherein the means for determining mean and standard deviation values includes means for locally adjusting the determined mean and standard deviation values of said system for the locally updated database, whereby the adjusted mean and standard deviation values for said system are adjusted for a particular patient population assessed by said system relative to mean and standard deviation values determined from the database from other medical risk assessment systems; means for storing predetermined requirements for risk data comprising the test data, the said at least one variable, the transformed data, the determined mean and the determined standard deviation; means for validating data when received, transformed and determined with regard to the predetermined requirements comprising means for range checking the test markers, the test data and the transformed data for the given patient; and means for indicating when the data does not meet the predetermined requirements.
Claim 12
Dependent Claim
26 words
The system according to claim 9, for use in accessing prenatal risks, wherein the test markers include at least one selected from AFP, hCG and uE3.
Claim 13
Dependent Claim
21 words
The system according to claim 10, wherein the variables include at least one selected from age, race, weight and diabetic status.
Claim 14
Dependent Claim
31 words
The system according to claim 9, wherein at least two markers are used and further comprising means for correlating the comparisons of the transformed data for the at least two markers.
Claim 15
Dependent Claim
36 words
The system according to claim 9, further comprising means for storing a plurality of letters, means for selecting a letter based on the transformed data for the given patient and means for printing the selected letter.
Claim 16
Dependent Claim
27 words
The system according to claim 9, wherein the validating means further comprises means for double copy comparing all data received from and written into the storing means.
Claim 17
Dependent Claim
25 words
The system according to claim 9, wherein the validating means further comprises means for maintaining an archival log of all data changes to the database.
Claim 18
Independent Claim
298 words
A system for assessing the medical risk of a given outcome for a patient, the system comprising: data input means receptive of test data from a given patient corresponding to at least one test marker for predicting the medical risk of a given outcome and at least one variable relating to the given patient; means for transforming the test data with the variable to produce transformed data for each test marker; means storing a database of transformed data from other medical risk assessment systems for previously assessed patients; means for determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; means for comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; and means for locally updating the database of said system with the actual occurrence for the given patient; wherein the means for determining mean and standard deviation values includes means for locally adjusting the determined mean and standard deviation values of said system for the locally updated database, whereby the adjusted mean and standard deviation values for said system are adjusted for a particular patient population assessed by said system relative to mean and standard deviation values determined from the database from other medical risk assessment systems; means for storing predetermined requirements for risk data comprising the test data, the said at least one variable, the transformed data, the determined mean and the determined standard deviation; means for validating data when received, transformed and determined With regard to the predetermined requirements comprising means for double copy comparing all data received from and written into the storing means; and means for indicating when the data does not meet the predetermined requirements.
Claim 19
Independent Claim
298 words
A system for assessing the medical risk of a given outcome for a patient, the system comprising: data input means receptive of test data from a given patient corresponding to at least one test marker for predicting the medical risk of a given outcome and at least one variable relating to the given patient; means for transforming the test data with the variable to produce transformed data for each test marker; means storing a database of transformed data from other medical risk assessment systems for previously assessed patients; means for determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; means for comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; and means for locally updating the database of said system with the actual occurrence for the given patient; wherein the means for determining mean and standard deviation values includes means for locally adjusting the determined mean and standard deviation values of said system for the locally updated database, whereby the adjusted mean and standard deviation values for said system are adjusted for a particular patient population assessed by said system relative to mean and standard deviation values determined from the database from other medical risk assessment systems; means for storing predetermined requirements for risk data comprising the test data, the said at least one variable, the transformed data, the determined mean and the determined standard deviation; means for validating data when received, transformed and determined With regard to the predetermined requirements comprising means for double copy comparing all data received from and written into the storing means; and means for indicating when the data does not meet the predetermined requirements.
Claim 20
Dependent Claim
26 words
The system according to claim 16, for use in accessing prenatal risks, wherein the test markers include at least one selected from AFP, hCG and uE3.
Claim 21
Dependent Claim
21 words
The system according to claim 17, wherein the variables include at least one selected from age, race, weight and diabetic status.
Claim 22
Dependent Claim
31 words
The system according to claim 16, wherein at least two markers are used and further comprising means for correlating the comparisons of the transformed data for the at least two markers.
Claim 23
Dependent Claim
36 words
The system according to claim 16, further comprising means for storing a plurality of letters, means for selecting a letter based on the transformed data for the given patient and means for printing the selected letter.
Claim 24
Dependent Claim
25 words
The system according to claim 16, wherein the validating means further comprises means for maintaining an archival log of all data changes to the database.
Claim 25
Independent Claim
296 words
A system for assessing the medical risk of a given outcome for a patient, the system comprising: data input means receptive of test data from a given patient corresponding to at least one test marker for predicting the medical risk of a given outcome and at least one variable relating to the given patient; means for transforming the test data with the variable to produce transformed data for each test marker; means storing a database of transformed data from other medical risk assessment systems for previously assessed patients; means for determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; means for comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; and means for locally updating the database of said system with the actual occurrence for the given patient; wherein the means for determining mean and standard deviation values includes means for locally adjusting the determined mean and standard deviation values of said system for the locally updated database, whereby the adjusted mean and standard deviation values for said system are adjusted for a particular patient population assessed by said system relative to mean and standard deviation values determined from the database from other medical risk assessment systems; means for storing predetermined requirements for risk data comprising the test data, the said at least one variable, the transformed data, the determined mean and the determined standard deviation; means for validating data when received, transformed and determined with regard to the predetermined requirements comprising means for maintaining an archival log of all data changes to the database; and means for indicating when the data does not meet the predetermined requirements.
Claim 26
Independent Claim
296 words
A system for assessing the medical risk of a given outcome for a patient, the system comprising: data input means receptive of test data from a given patient corresponding to at least one test marker for predicting the medical risk of a given outcome and at least one variable relating to the given patient; means for transforming the test data with the variable to produce transformed data for each test marker; means storing a database of transformed data from other medical risk assessment systems for previously assessed patients; means for determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; means for comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; and means for locally updating the database of said system with the actual occurrence for the given patient; wherein the means for determining mean and standard deviation values includes means for locally adjusting the determined mean and standard deviation values of said system for the locally updated database, whereby the adjusted mean and standard deviation values for said system are adjusted for a particular patient population assessed by said system relative to mean and standard deviation values determined from the database from other medical risk assessment systems; means for storing predetermined requirements for risk data comprising the test data, the said at least one variable, the transformed data, the determined mean and the determined standard deviation; means for validating data when received, transformed and determined with regard to the predetermined requirements comprising means for maintaining an archival log of all data changes to the database; and means for indicating when the data does not meet the predetermined requirements.
Claim 27
Dependent Claim
26 words
The system according to claim 22, for use in accessing prenatal risks, wherein the test markers include at least one selected from AFP, hCG and uE3.
Claim 28
Dependent Claim
21 words
The system according to claim 23, wherein the variables include at least one selected from age, race, weight and diabetic status.
Claim 29
Dependent Claim
31 words
The system according to claim 22, wherein at least two markers are used and further comprising means for correlating the comparisons of the transformed data for the at least two markers.
Claim 30
Dependent Claim
36 words
The system according to claim 22, further comprising means for storing a plurality of letters, means for selecting a letter based on the transformed data for the given patient and means for printing the selected letter.
Claim 31
Dependent Claim
68 words
The system according to claim 22, wherein the validating means further comprises means for checking the integrity of the database for each comparison with the data therein and each update of the data therein, means for range checking the test markers, the test data and the transformed data for the given patient and means for double copy comparing all data received from and written into the storing means.
Claim 32
Independent Claim
252 words
A system for assessing the medical risk of a given outcome for a patient, the system comprising: data input means receptive of test data from a given patient corresponding to at least one test marker for predicting the medical risk of a given outcome and at least one variable relating to the given patient; means for transforming the test data with the variable to produce transformed data for each test marker; means storing a database of transformed data from other medical risk assessment systems for previously assessed patients; means for determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; means for comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; means for locally updating the database of said system with the actual occurrence for the given patient; wherein the means for determining mean and standard deviation values includes means for locally adjusting the determined mean and standard deviation values of said system for the locally updated database, whereby the adjusted mean and standard deviation values for said system are adjusted for a particular patient population assessed by said system relative to mean and standard deviation values determined from the database from other medical risk assessment systems; means for storing a plurality of letters; means for selecting a letter based on the transformed data for the given patient; and means for printing the selected letter.
Claim 33
Independent Claim
252 words
A system for assessing the medical risk of a given outcome for a patient, the system comprising: data input means receptive of test data from a given patient corresponding to at least one test marker for predicting the medical risk of a given outcome and at least one variable relating to the given patient; means for transforming the test data with the variable to produce transformed data for each test marker; means storing a database of transformed data from other medical risk assessment systems for previously assessed patients; means for determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; means for comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; means for locally updating the database of said system with the actual occurrence for the given patient; wherein the means for determining mean and standard deviation values includes means for locally adjusting the determined mean and standard deviation values of said system for the locally updated database, whereby the adjusted mean and standard deviation values for said system are adjusted for a particular patient population assessed by said system relative to mean and standard deviation values determined from the database from other medical risk assessment systems; means for storing a plurality of letters; means for selecting a letter based on the transformed data for the given patient; and means for printing the selected letter.
Claim 34
Dependent Claim
64 words
The system according to claim 28, further comprising means for storing predetermined requirements for risk data comprising the test data, said at least one variable, the transformed data, the determined mean and the determined standard deviation, means for validating data when received, transformed and determined with regard to the predetermined requirements and means for indicating when the data does not meet the predetermined requirements.
Claim 35
Dependent Claim
33 words
The system according to claim 29, wherein the validating means comprises means for checking the integrity of the database for each comparison with the data therein and each update of the data therein.
Claim 36
Dependent Claim
29 words
The system according to claim 29, wherein the validating means comprises means for range checking the test markers, the test data and the transformed data for the given patient.
Claim 37
Dependent Claim
26 words
The system according to claim 29, wherein the validating means comprises means for double copy comparing all data received from and written into the storing means.
Claim 38
Dependent Claim
24 words
The system according to claim 29, wherein the validating means comprises means for maintaining an archival log of all data changes to the database.
Claim 39
Dependent Claim
26 words
The system according to claim 28, for use in accessing prenatal risks, wherein the test markers include at least one selected from AFP, hCG and uE3.
Claim 40
Dependent Claim
21 words
The system according to claim 34, wherein the variables include at least one selected from age, race, weight and diabetic status.
Claim 41
Dependent Claim
31 words
The system according to claim 28, wherein at least two markers are used and further comprising means for correlating the comparisons of the transformed data for the at least two markers.
Claim 42
Independent Claim
257 words
A method for assessing the medical risk of a given outcome for a patient, comprising the steps of: obtaining test data from a given patient from a particular patient population corresponding to at least one test marker for predicting the medical risk of a given outcome; obtaining at least one variable relating to the given patient and transforming the test data with the variable to produce transformed data for each test marker; providing a database of transformed data from previously assessed patients from other patient populations; determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; locally updating the database with the actual occurrence for the given patient and locally adjusting the determined mean and standard deviation values, whereby the adjusted mean and standard deviation values are adjusted for the particular patient population relative to mean and standard deviation values determined from the database from other patient populations; providing predetermined requirements for risk data comprising the test data, the said at least one variable, the transformed data, the determined mean and the determined standard deviation; validating the data when received, transformed and determined with regard to the predetermined requirements by checking the integrity of the database for each comparison with the data therein and each update of the data therein; and indicating when the data does not meet the predetermined requirements.
Claim 43
Independent Claim
257 words
A method for assessing the medical risk of a given outcome for a patient, comprising the steps of: obtaining test data from a given patient from a particular patient population corresponding to at least one test marker for predicting the medical risk of a given outcome; obtaining at least one variable relating to the given patient and transforming the test data with the variable to produce transformed data for each test marker; providing a database of transformed data from previously assessed patients from other patient populations; determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; locally updating the database with the actual occurrence for the given patient and locally adjusting the determined mean and standard deviation values, whereby the adjusted mean and standard deviation values are adjusted for the particular patient population relative to mean and standard deviation values determined from the database from other patient populations; providing predetermined requirements for risk data comprising the test data, the said at least one variable, the transformed data, the determined mean and the determined standard deviation; validating the data when received, transformed and determined with regard to the predetermined requirements by checking the integrity of the database for each comparison with the data therein and each update of the data therein; and indicating when the data does not meet the predetermined requirements.
Claim 44
Dependent Claim
26 words
The method according to claim 37, for use in accessing prenatal risk, wherein the test markers include at least one selected from AFP, hCG and uE3.
Claim 45
Dependent Claim
21 words
The method according to claim 38, wherein the variables include at least one selected from age, race, weight and diabetic status.
Claim 46
Dependent Claim
29 words
The method according to claim 37, wherein at least two markers are used and further comprising correlating the comparisons of the transformed data for the at least two markers.
Claim 47
Dependent Claim
30 words
The method according to claim 37, further comprising storing a plurality of letters, selecting a letter based on the transformed data for the given patient and printing the selected letter.
Claim 48
Dependent Claim
29 words
The method according to claim 37, wherein the step of validating further comprises range checking the test markers, the test data and the transformed data for the given patient.
Claim 49
Dependent Claim
25 words
The method according to claim 37, wherein the step of validating further comprises double copy comparing all data received from the database and written therein.
Claim 50
Dependent Claim
24 words
The method according to claim 37, wherein the step of validating further comprises maintaining an archival log of all data changes to the database.
Claim 51
Independent Claim
253 words
A method for assessing the medical risk of a given outcome for a patient, comprising the steps of: obtaining test data from a given patient from a particular patient population corresponding to at least one test marker for predicting the medical risk of a given outcome; obtaining at least one variable relating to the given patient and transforming the test data with the variable to produce transformed data for each test marker; providing a database of transformed data from previously assessed patients from other patient populations; determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; locally updating the database with the actual occurrence for the given patient and locally adjusting the determined mean and standard deviation values, whereby the adjusted mean and standard deviation values are adjusted for the particular patient population relative to mean and standard deviation values determined from the database from other patient populations; providing predetermined requirements for risk data comprising the test data, the said at least one variable, the transformed data, the determined mean and the determined standard deviation; validating the data when received, transformed and determined with regard to the predetermined requirements by range checking the test markers, the test data and the transformed data for the given patient; and indicating when the data does not meet the predetermined requirements.
Claim 52
Independent Claim
253 words
A method for assessing the medical risk of a given outcome for a patient, comprising the steps of: obtaining test data from a given patient from a particular patient population corresponding to at least one test marker for predicting the medical risk of a given outcome; obtaining at least one variable relating to the given patient and transforming the test data with the variable to produce transformed data for each test marker; providing a database of transformed data from previously assessed patients from other patient populations; determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; locally updating the database with the actual occurrence for the given patient and locally adjusting the determined mean and standard deviation values, whereby the adjusted mean and standard deviation values are adjusted for the particular patient population relative to mean and standard deviation values determined from the database from other patient populations; providing predetermined requirements for risk data comprising the test data, the said at least one variable, the transformed data, the determined mean and the determined standard deviation; validating the data when received, transformed and determined with regard to the predetermined requirements by range checking the test markers, the test data and the transformed data for the given patient; and indicating when the data does not meet the predetermined requirements.
Claim 53
Dependent Claim
26 words
The method according to claim 45, for use in accessing prenatal risk, wherein the test markers include at least one selected from AFP, hCG and uE3.
Claim 54
Dependent Claim
21 words
The method according to claim 46, wherein the variables include at least one selected from age, race, weight and diabetic status.
Claim 55
Dependent Claim
29 words
The method according to claim 45, wherein at least two markers are used and further comprising correlating the comparisons of the transformed data for the at least two markers.
Claim 56
Dependent Claim
30 words
The method according to claim 45, further comprising storing a plurality of letters, selecting a letter based on the transformed data for the given patient and printing the selected letter.
Claim 57
Dependent Claim
25 words
The method according to claim 45, wherein the step of validating further comprises double copy comparing all data received from the database and written therein.
Claim 58
Dependent Claim
24 words
The method according to claim 45, wherein the step of validating further comprises maintaining an archival log of all data changes to the database.
Claim 59
Independent Claim
249 words
A method for assessing the medical risk of a given outcome for a patient, comprising the steps of: obtaining test data from a given patient from a particular patient population corresponding to at least one test marker for predicting the medical risk of a given outcome; obtaining at least one variable relating to the given patient and transforming the test data with the variable to produce transformed data for each test marker; providing a database of transformed data from previously assessed patients from other patient populations; determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; locally updating the database with the actual occurrence for the given patient and locally adjusting the determined mean and standard deviation values, whereby the adjusted mean and standard deviation values are adjusted for the particular patient population relative to mean and standard deviation values determined from the database from other patient populations; providing predetermined requirements for risk data comprising the test data, the said at least one variable, the transformed data, the determined mean and the determined standard deviation; validating the data when received, transformed and determined with regard to the predetermined requirements by double copy comparing all data received from the database and written therein; and indicating when the data does not meet the predetermined requirements.
Claim 60
Independent Claim
249 words
A method for assessing the medical risk of a given outcome for a patient, comprising the steps of: obtaining test data from a given patient from a particular patient population corresponding to at least one test marker for predicting the medical risk of a given outcome; obtaining at least one variable relating to the given patient and transforming the test data with the variable to produce transformed data for each test marker; providing a database of transformed data from previously assessed patients from other patient populations; determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; locally updating the database with the actual occurrence for the given patient and locally adjusting the determined mean and standard deviation values, whereby the adjusted mean and standard deviation values are adjusted for the particular patient population relative to mean and standard deviation values determined from the database from other patient populations; providing predetermined requirements for risk data comprising the test data, the said at least one variable, the transformed data, the determined mean and the determined standard deviation; validating the data when received, transformed and determined with regard to the predetermined requirements by double copy comparing all data received from the database and written therein; and indicating when the data does not meet the predetermined requirements.
Claim 61
Dependent Claim
26 words
The method according to claim 52, for use in accessing prenatal risk, wherein the test markers include at least one selected from AFP, hCG and uE3.
Claim 62
Dependent Claim
21 words
The method according to claim 53, wherein the variables include at least one selected from age, race, weight and diabetic status.
Claim 63
Dependent Claim
29 words
The method according to claim 52, wherein at least two markers are used and further comprising correlating the comparisons of the transformed data for the at least two markers.
Claim 64
Dependent Claim
30 words
The method according to claim 52, further comprising storing a plurality of letters, selecting a letter based on the transformed data for the given patient and printing the selected letter.
Claim 65
Dependent Claim
23 words
The method according to claim 52, wherein the step of validating comprises maintaining an archival log of all data changes to the database.
Claim 66
Independent Claim
248 words
A method for assessing the medical risk of a given outcome for a patient, comprising the steps of: obtaining test data from a given patient from a particular patient population corresponding to at least one test marker for predicting the medical risk of a given outcome; obtaining at least one variable relating to the given patient and transforming the test data with the variable to produce transformed data for each test marker; providing a database of transformed data from previously assessed patients from other patient populations; determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; locally updating the database with the actual occurrence for the given patient and locally adjusting the determined mean and standard deviation values, whereby the adjusted mean and standard deviation values are adjusted for the particular patient population relative to mean and standard deviation values determined from the database from other patient populations; providing predetermined requirements for risk data comprising the test data, the said at least one variable, the transformed data, the determined mean and the determined standard deviation; validating the data when received, transformed and determined with regard to the predetermined requirements by maintaining an archival log of all data changes to the database; and indicating when the data does not meet the predetermined requirements.
Claim 67
Independent Claim
248 words
A method for assessing the medical risk of a given outcome for a patient, comprising the steps of: obtaining test data from a given patient from a particular patient population corresponding to at least one test marker for predicting the medical risk of a given outcome; obtaining at least one variable relating to the given patient and transforming the test data with the variable to produce transformed data for each test marker; providing a database of transformed data from previously assessed patients from other patient populations; determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; locally updating the database with the actual occurrence for the given patient and locally adjusting the determined mean and standard deviation values, whereby the adjusted mean and standard deviation values are adjusted for the particular patient population relative to mean and standard deviation values determined from the database from other patient populations; providing predetermined requirements for risk data comprising the test data, the said at least one variable, the transformed data, the determined mean and the determined standard deviation; validating the data when received, transformed and determined with regard to the predetermined requirements by maintaining an archival log of all data changes to the database; and indicating when the data does not meet the predetermined requirements.
Claim 68
Dependent Claim
26 words
The method according to claim 58, for use in accessing prenatal risk, wherein the test markers include at least one selected from AFP, hCG and uE3.
Claim 69
Dependent Claim
21 words
The method according to claim 59, wherein the variables include at least one selected from age, race, weight and diabetic status.
Claim 70
Dependent Claim
29 words
The method according to claim 58, wherein at least two markers are used and further comprising correlating the comparisons of the transformed data for the at least two markers.
Claim 71
Dependent Claim
30 words
The method according to claim 58, further comprising storing a plurality of letters, selecting a letter based on the transformed data for the given patient and printing the selected letter.
Claim 72
Dependent Claim
62 words
The method according to claim 58, wherein the step of validating further comprises checking the integrity of the database for each comparison with the data therein and each update of the data therein, range checking the test markers, the test data and the transformed data for the given patient and double copy comparing all data received from the database and written therein.
Claim 73
Independent Claim
205 words
A method for assessing the medical risk of a given outcome for a patient, comprising the steps of: obtaining test data from a given patient from a particular patient population corresponding to at least one test marker for predicting the medical risk of a given outcome; obtaining at least one variable relating to the given patient and transforming the test data with the variable to produce transformed data for each test marker; providing a database of transformed data from previously assessed patients from other patient populations; determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; locally updating the database with the actual occurrence for the given patient and adjusting the determined mean and standard deviation values, whereby the adjusted mean and standard deviation values are adjusted for the particular patient population relative to mean and standard deviation values determined from the database from other patient populations; storing a plurality of letters; selecting a letter based on the transformed data for the given patient; and printing the selected letter.
Claim 74
Independent Claim
205 words
A method for assessing the medical risk of a given outcome for a patient, comprising the steps of: obtaining test data from a given patient from a particular patient population corresponding to at least one test marker for predicting the medical risk of a given outcome; obtaining at least one variable relating to the given patient and transforming the test data with the variable to produce transformed data for each test marker; providing a database of transformed data from previously assessed patients from other patient populations; determining mean and standard deviation values from the database in accordance with the actual occurrence of the given outcome for previously assessed patients; comparing the transformed data with the mean and standard deviation values to assess the likelihood of the given outcome for the given patient; locally updating the database with the actual occurrence for the given patient and adjusting the determined mean and standard deviation values, whereby the adjusted mean and standard deviation values are adjusted for the particular patient population relative to mean and standard deviation values determined from the database from other patient populations; storing a plurality of letters; selecting a letter based on the transformed data for the given patient; and printing the selected letter.
Claim 75
Dependent Claim
59 words
The method according to claim 64, further comprising providing predetermined requirements for risk data comprising the test data, said at least one variable, the transformed data, the determined mean and the determined standard deviation, validating the data when received, transformed and determined with regard to the predetermined requirements and indicating when the data does not meet the predetermined requirements.
Claim 76
Dependent Claim
26 words
The method according to claim 64, for use in accessing prenatal risk, wherein the test markers include at least one selected from AFP, hCG and uE3.
Claim 77
Dependent Claim
21 words
The method according to claim 66, wherein the variables include at least one selected from age, race, weight and diabetic status.
Claim 78
Dependent Claim
29 words
The method according to claim 64, wherein at least two markers are used and further comprising correlating the comparisons of the transformed data for the at least two markers.
Claim 79
Dependent Claim
33 words
The method according to claim 65, wherein the step of validating further comprises checking the integrity of the database for each comparison with the data therein and each update of the data therein.
Claim 80
Dependent Claim
29 words
The method according to claim 64, wherein the step of validating further comprises range checking the test markers, the test data and the transformed data for the given patient.
Claim 81
Dependent Claim
25 words
The method according to claim 64, wherein the step of validating further comprises double copy comparing all data received from the database and written therein.
Claim 82
Dependent Claim
24 words
The method according to claim 64, wherein the step of validating further comprises maintaining an archival log of all data changes to the database.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2000-01-14 | 2000-07-15 | 2001-01-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-01-14 | 2004-07-15 | 2005-01-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-01-14 | 2008-07-15 | 2009-01-14 | $7700.00 | Window Closed / Lapsed |