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US5584877A Expired / Lapsed US ⏱️ 0.0 years remaining

Antibacterial vascular prosthesis and surgical suture

Assignee: Sumitomo Electric Industries Ltd
•
Filing: 1994-06-23
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Granted: 1996-12-17
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Expires: 2014-06-23
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Abstract

Abstract An antibacterial vascular prosthesis obtained by winding a tube, fiber or sheet formed from a polymeric material and combined with an antibacterial substance on the outer surface of a vascular prosthesis composed of a tubular porous body formed of a synthetic resin is provided. The antibacterial vascular prosthesis can exhibit an antibacterial activity over a long period of time without impairing the porous structure, antithrombogenicity and histocompatibility inherent in the vascular prosthesis composed of the tubular porous body formed of the synthetic resin. An antibacterial surgical suture comprising a tube or fiber formed from a polymeric material and combined with an antibacterial substance is also provided.

Inventors

  • 👤 Shinichi Miyake
  • 👤 Shigehiko Ito
  • 👤 Yumiko Oka
  • 👤 Jun-ichi Kambayashi
  • 👤 Kazuhiro Okahara

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 14:25
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/54; A61L17/00; A61L17/005; A61L27/28; A61L27/34; A61L27/40; A61L27/44; A61L27/48; A61L27/507; A61L2300/00; A61L2300/10; A61L2300/102; A61L2300/104; A61L2300/40; A61L2300/404; A61L2300/406

Claims Analysis

Total Claims: 15
Claim 1
Independent Claim 88 words
An antibacterial vascular prosthesis obtained by winding a tube, fiber or sheet formed from a polymeric material and combined with an antibacterial substance on the outer surface of a vascular prosthesis composed of a tubular porous body formed of a synthetic resin, wherein the tube, fiber or sheet combined with an antibacterial substance is wound on the outer surface of the vascular prosthesis such that portions of the outer surface of the antibacterial vascular prosthesis are uncovered and the porosity of the antibacterial vascular prosthesis is substantially unimpaired.
Claim 2
Dependent Claim 88 words
An antibacterial vascular prosthesis obtained by winding a tube, fiber or sheet formed from a polymeric material and combined with an antibacterial substance on the outer surface of a vascular prosthesis composed of a tubular porous body formed of a synthetic resin, wherein the tube, fiber or sheet combined with an antibacterial substance is wound on the outer surface of the vascular prosthesis such that portions of the outer surface of the antibacterial vascular prosthesis are uncovered and the porosity of the antibacterial vascular prosthesis is substantially unimpaired.
Claim 3
Dependent Claim 55 words
The antibacterial vascular prosthesis according to claim 1, wherein the tube, fiber or sheet combined with the antibacterial substance is obtained by impregnating with and/or depositing the antibacterial substance into and/or on at least part of the pores, inner surface and outer surface of a porous tube, fiber or sheet formed from the polymeric material.
Claim 4
Dependent Claim 28 words
The antibacterial vascular prosthesis according to claim 2, wherein the polymeric material from which the porous tube, fiber or sheet is formed is polytetrafluoroethylene or a tetrafluoroethylene-hexafluoropropylene copolymer.
Claim 5
Dependent Claim 62 words
The antibacterial vascular prosthesis according to claim 1, wherein the tube, fiber or sheet combined with the antibacterial substance is obtained by impregnating with and/or depositing a mixture of a biodegradable polymer and the antibacterial substance into and/or on at least part of the pores, inner surface and outer surface of a porous tube, fiber or sheet formed from the polymeric material.
Claim 6
Dependent Claim 28 words
The antibacterial vascular prosthesis according to claim 4, wherein the polymeric material from which the porous tube, fiber or sheet is formed is polytetrafluoroethylene or a tetrafluoroethylene-hexafluoropropylene copolymer.
Claim 7
Dependent Claim 24 words
The antibacterial vascular prosthesis according to claim 4, wherein the biodegradable polymer is selected from agarose, dextran, polylactic acid, gelatin, fibrinogen, chitin and chitosan.
Claim 8
Dependent Claim 32 words
The antibacterial vascular prosthesis according to claim 1, wherein the tube, fiber or sheet combined with an antibacterial substance is formed from a mixture of a biodegradable polymer and the antibacterial substance.
Claim 9
Dependent Claim 24 words
The antibacterial vascular prosthesis according to claim 7, wherein the biodegradable polymer is selected from agarose, dextran, polylactic acid, gelatin, fibrinogen, chitin and chitosan.
Claim 10
Dependent Claim 19 words
The antibacterial vascular prosthesis according to claim 1, wherein the antibacterial substance is an antibiotic or a heavy metal.
Claim 11
Dependent Claim 21 words
The antibacterial vascular prosthesis according to claim 9, wherein the antibiotic is selected from β-lactam, aminoglycoside, chloramphenicol, tetracycline, macrolide and lincomycin.
Claim 12
Dependent Claim 16 words
The antibacterial vascular prosthesis according to claim 9, wherein the heavy metal is a silver compound.
Claim 13
Dependent Claim 53 words
The antibacterial vascular prosthesis according to claim 1, wherein the outer diameter of the tube combined with the antibacterial substance, the size of the fiber combined with the antibacterial substance, or the thickness and width of the sheet combined with the antibacterial substance are smaller than the outer diameter of the vascular prosthesis.
Claim 14
Dependent Claim 57 words
The antibacterial vascular prosthesis according to claim 1, wherein the outer diameter of the tube combined with the antibacterial substance, the size of the fiber combined with the antibacterial substance, or the thickness and width of the sheet combined with the antibacterial substance are about a half or smaller of the outer diameter of the vascular prosthesis.
Claim 15
Dependent Claim 31 words
The antibacterial vascular prosthesis according to claim 1, wherein the tubular porous body composing the vascular prosthesis and made of a synthetic resin is a tubular porous body formed from polytetrafluoroethylene.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1999-12-17 2000-06-17 2000-12-17 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2003-12-17 2004-06-17 2004-12-17 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2007-12-17 2008-06-17 2008-12-17 $7700.00 Window Closed / Lapsed

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