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US5578576A Expired / Lapsed US ⏱️ 0.0 years remaining

Method and composition for treating intestinal wounds or ulcers

Assignee: Dalhousie University
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Filing: 1994-09-02
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Granted: 1996-11-26
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Expires: 2014-09-02
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Abstract

Abstract The present invention provides a method for aiding healing or preventing the onset of intestinal wounds or ulcers in a patient. In addition, the present invention provides a method for reducing, or preventing, the gastrointestinal side effects associated with the administration of a nonsteroidal anti-inflammatory drug. Pursuant to the present invention, the composition includes a protein source, a carbohydrate source, a fat source, and a specialized vitamin and mineral profile.

Inventors

  • 👤 Desmond Leddin

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-09 07:21
CPC Classifications
A; A61; A61K; A61K45/00; A61K45/06; A61P; A61P1/00; A61P1/04; A61P29/00

Claims Analysis

Total Claims: 22
Claim 1
Independent Claim 91 words
A method for aiding healing of intestinal wounds or ulcers in a patient receiving a non-steroidal anti-inflammatory drug comprising the step of administering to the patient a therapeutically effective amount of a composition comprising: a protein source comprising approximately 14% to about 25% of the total calories; a carbohydrate source comprising approximately 40% to about 60% of the total calories; and a fat source comprising approximately 33% to about 44% of the total calories, the fat source including a medium-chain triglyceride to long chain triglyceride ratio of approximately 1:4 to 4:1.
Claim 2
Independent Claim 91 words
A method for aiding healing of intestinal wounds or ulcers in a patient receiving a non-steroidal anti-inflammatory drug comprising the step of administering to the patient a therapeutically effective amount of a composition comprising: a protein source comprising approximately 14% to about 25% of the total calories; a carbohydrate source comprising approximately 40% to about 60% of the total calories; and a fat source comprising approximately 33% to about 44% of the total calories, the fat source including a medium-chain triglyceride to long chain triglyceride ratio of approximately 1:4 to 4:1.
Claim 3
Dependent Claim 12 words
The method of claim 1 wherein the protein source includes hydrolyzed whey.
Claim 4
Dependent Claim 11 words
The method of claim 1 wherein the protein source includes casein.
Claim 5
Dependent Claim 20 words
The method of claim 1 wherein the carbohydrate source is selected from the group consisting of: maltodextrin and corn starch.
Claim 6
Dependent Claim 17 words
The method of claim 1 wherein the fat source includes approximately 25% to 75% medium chain triglycerides.
Claim 7
Dependent Claim 19 words
The method of claim 1 wherein the composition includes fractionated coconut oil as a source of medium chain triglycerides.
Claim 8
Dependent Claim 11 words
The method of claim 1 wherein the composition is administered enterally.
Claim 9
Independent Claim 114 words
A method for inhibiting the gastrointestinal side effects suffered by a patient receiving a nonsteroidal anti-inflammatory drug comprising the step of administering to the patient a therapeutically effective amount of a composition comprising: a protein source comprising approximately 14% to about 25% of the total calories; a carbohydrate source comprising approximately 40% to about 60% of the total calories; a fat source comprising approximately 33% to about 44% of the total calories, the fat source including a medium-chain triglyceride to long chain triglyceride ratio of approximately 1:4 to 4:1; and a source of vitamins and minerals including approximately 75% to about 150% of the recommended daily allowance per 1500 Kcal of the composition administered.
Claim 10
Independent Claim 114 words
A method for inhibiting the gastrointestinal side effects suffered by a patient receiving a nonsteroidal anti-inflammatory drug comprising the step of administering to the patient a therapeutically effective amount of a composition comprising: a protein source comprising approximately 14% to about 25% of the total calories; a carbohydrate source comprising approximately 40% to about 60% of the total calories; a fat source comprising approximately 33% to about 44% of the total calories, the fat source including a medium-chain triglyceride to long chain triglyceride ratio of approximately 1:4 to 4:1; and a source of vitamins and minerals including approximately 75% to about 150% of the recommended daily allowance per 1500 Kcal of the composition administered.
Claim 11
Dependent Claim 12 words
The method of claim 8 wherein the protein source includes hydrolyzed whey.
Claim 12
Dependent Claim 11 words
The method of claim 8 wherein the protein source includes casein.
Claim 13
Dependent Claim 20 words
The method of claim 8 wherein the carbohydrate source is selected from the group consisting of: maltodextrin and corn starch.
Claim 14
Dependent Claim 17 words
The method of claim 8 wherein the fat source includes approximately 25% to 75% medium chain triglycerides.
Claim 15
Dependent Claim 19 words
The method of claim 8 wherein the composition includes fractionated coconut oil as a source of medium chain triglycerides.
Claim 16
Dependent Claim 11 words
The method of claim 8 wherein the composition is administered enterally.
Claim 17
Dependent Claim 16 words
The method of claim 8 wherein the composition is administered contemporaneously with the nonsteroidal anti-inflammatory drug.
Claim 18
Dependent Claim 12 words
The method of claim 8 wherein the nonsteroidal anti-inflammatory drug is indomethacin.
Claim 19
Dependent Claim 19 words
The method of claim 8 wherein the composition is administered on the same day as the nonsteroidal anti-inflammatory drug.
Claim 20
Independent Claim 92 words
A method for treating arthritis in a patient suffering from same comprising the steps of: administering a therapeutically effective amount of a nonsteroidal anti-inflammatory drug; and administering a therapeutically effective amount of a composition comprising: a protein source comprising approximately 14% to about 25% of the total calories; a carbohydrate source comprising approximately 40% to about 60% of the total calories; and a fat source comprising approximately 33% to about 44% of the total calories, the fat source including a medium-chain triglyceride to long chain triglyceride ratio of approximately 1:4 to 4:1.
Claim 21
Independent Claim 92 words
A method for treating arthritis in a patient suffering from same comprising the steps of: administering a therapeutically effective amount of a nonsteroidal anti-inflammatory drug; and administering a therapeutically effective amount of a composition comprising: a protein source comprising approximately 14% to about 25% of the total calories; a carbohydrate source comprising approximately 40% to about 60% of the total calories; and a fat source comprising approximately 33% to about 44% of the total calories, the fat source including a medium-chain triglyceride to long chain triglyceride ratio of approximately 1:4 to 4:1.
Claim 22
Dependent Claim 11 words
The method of claim 18 wherein the composition is administered enterally.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1999-11-26 2000-05-27 2000-11-26 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2003-11-26 2004-05-27 2004-11-26 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2007-11-26 2008-05-27 2008-11-26 $7700.00 Window Closed / Lapsed

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