Patent US3068544A successfully refreshed from Google Patents.
Patent US5577089A successfully refreshed from Google Patents.
US5577089A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Device and method for analysis of bone morphology
Assignee: GE Lunar Corp
•
Filing: 1995-06-07
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Granted: 1996-11-19
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Expires: 2015-06-07
Abstract
Abstract A method for automatically analyzing the morphometry of bones from data obtained by lateral digital scans of the bone obtains a matrix of data values assembled from an x-ray scan. The matrix is analyzed to locate an axis of the bone from which subsequent measures may be referenced. Once the axis is fixed, one or more of several useful indicia of bone condition such a length or interbone spacing can be calculated. The measures are compared to a set of reference values that has been normalized to lumbar vertebra of the patient.
Inventors
- 👤 Richard B. Mazess
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 07:28
CPC Classifications
A; A61; A61B; A61B6/00; A61B6/50; A61B6/505; A61B6/02; A61B6/03; A61B6/032; A61B6/40; A61B6/4035; A61B6/405; A61B6/4064; A61B6/4085; A61B6/46; A61B6/461; A61B6/463; A61B6/48; A61B6/482; A61F; A61F2/00; A61F2/02; A61F2/28; A61F2/30; A61F2/46; A61F2/4657; A61F2/468; G; G01; G01T; G01T1/00; G01T1/16; G01T1/161; G01T1/163; G06; G06T; G06T7/00; G06T7/60; A61B6/4042; A61F2/32; A61F2/36; A61F2/3662; A61F2/367; A61F2/3676; A61F2/44; A61F2002/30001; A61F2002/30003; A61F2002/3006; A61F2002/3008; A61F2240/00; A61F2240/001; A61F2240/008; A61F2250/00; A61F2250/0058; A61F2250/0096; A61F2250/0098; A61F2310/00; A61F2310/00005; A61F2310/00011; A61F2310/00179; G06T2207/00; G06T2207/30; G06T2207/30004; G06T2207/30008; G06T2207/30012; G06T2207/30172
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
71 words
A method of evaluating a human spine comprising the steps of: (a) measuring the height of at least two vertebrae; (b) combining the measured heights to produce a measured index; (c) measuring the height of at least one vertebra not measured in step (a); and (d) comparing the measured height from step (c) to a reference height of a corresponding vertebra of a healthy individual as normalized by the measured index.
Claim 2
Independent Claim
71 words
A method of evaluating a human spine comprising the steps of: (a) measuring the height of at least two vertebrae; (b) combining the measured heights to produce a measured index; (c) measuring the height of at least one vertebra not measured in step (a); and (d) comparing the measured height from step (c) to a reference height of a corresponding vertebra of a healthy individual as normalized by the measured index.
Claim 3
Dependent Claim
21 words
The method of claim 1 wherein the at least two vertebrae producing the measured index are selected from the lumbar vertebrae.
Claim 4
Dependent Claim
30 words
The method of claim 1 wherein the reference height of corresponding vertebra of a healthy individual is a composite value of the heights of corresponding vertebrae from many healthy individuals.
Claim 5
Dependent Claim
31 words
The method of claim 1 wherein the reference height of the corresponding vertebra of a healthy individual is an average value of the heights of corresponding vertebrae from many healthy individuals.
Claim 6
Dependent Claim
51 words
The method of claim 1 wherein the reference height is normalized by scaling the reference height by a fraction the numerator of which is the measured index and the denominator of which is a standard index, the standard index being a mathematical combination of heights of vertebrae of the healthy individual.
Claim 7
Dependent Claim
51 words
The method of claim 1 wherein the reference height is normalized by scaling the measured height by a fraction the numerator of which is a standard index and the denominator of which is the measured index, the standard index being a mathematical combination of heights of vertebrae of the healthy individual.
Claim 8
Dependent Claim
48 words
The method of claim 1 wherein in step (a) at least three vertebrae are measured and wherein step (b) produces the measured index from only those vertebrae measured in step (a) whose measured heights deviate from an average of those measured heights by less than a predetermined value.
Claim 9
Independent Claim
127 words
An apparatus for evaluating a patient's spine comprising: (a) a radiation imager positioned about a patient to collect an array of data indicating the dimensions of multiple vertebra of the spine: (b) an electronic computer receiving the array of data and operating according to a stored program to: (i) measure the height of at least two vertebrae; (ii) combine the measured heights to produce a measured index; (iii) measure the height of at least one vertebrae not measured at (i); and (iv) compare the measured height from step (iii) to a reference height of a corresponding vertebra of a healthy individual as normalized by the measured index; (c) an output display communicating with the computer to allow an operator to review the comparison performed by the computer.
Claim 10
Independent Claim
127 words
An apparatus for evaluating a patient's spine comprising: (a) a radiation imager positioned about a patient to collect an array of data indicating the dimensions of multiple vertebra of the spine: (b) an electronic computer receiving the array of data and operating according to a stored program to: (i) measure the height of at least two vertebrae; (ii) combine the measured heights to produce a measured index; (iii) measure the height of at least one vertebrae not measured at (i); and (iv) compare the measured height from step (iii) to a reference height of a corresponding vertebra of a healthy individual as normalized by the measured index; (c) an output display communicating with the computer to allow an operator to review the comparison performed by the computer.
Claim 11
Dependent Claim
22 words
The apparatus of claim 8 wherein the electronic computer combines the measured heights of two lumbar vertebrae to produce the measured index.
Claim 12
Dependent Claim
37 words
The apparatus of claim 8 wherein the reference height of a corresponding vertebrae of a healthy individual is a composite value of the heights of corresponding vertebrae from many actual healthy individuals stored in the electronic computer.
Claim 13
Dependent Claim
36 words
The apparatus of claim 8 wherein the reference height of the corresponding vertebra of a healthy individual is an average value of the heights of corresponding vertebrae from many healthy individuals, stored in the electronic computer.
Claim 14
Dependent Claim
54 words
The apparatus of claim 8 wherein the electronic computer normalizes the reference height by scaling the reference height by a fraction the numerator of which is the measured index and the denominator of which is a standard index, the standard index being a mathematical combination of heights of the vertebrae of the healthy individual.
Claim 15
Dependent Claim
54 words
The apparatus of claim 8 wherein the electronic computer normalizes the reference height by scaling the measured height by a fraction the numerator of which is a standard index and the denominator of which is a measured index, the standard index being a mathematical combination of heights of the vertebrae of the healthy individual.
Claim 16
Dependent Claim
48 words
The apparatus of claim 8 wherein the electronic computer, at (i) measures at least three vertebrae and wherein at (ii) produces the measured index from only those vertebrae measured at (i) whose measured heights deviate from an average of those measured heights by less than a predetermined value.
Claim 17
Independent Claim
128 words
A method of in vivo morphometric analyses of vertebra of the spine comprising the steps of: (a) collecting measured data indicating dimensions of multiple vertebrae; (b) measuring the height of at least two vertebrae in the measured data; (c) mathematically combining the measured heights to produce a measured index; (d) geometrically scaling reference data of spine representative of a healthy individual according to the measured index to produce scaled reference data; (e) superimposing the scaled reference data over the measured data to define at least one analyses zone; (f) identifying a morphometric fiducial point with respect to the analyses zone and the measured data of a vertebrae; and (g) measuring a distance between the fiducial point and one other fiducial point as a morphometric measure of the vertebrae.
Claim 18
Independent Claim
128 words
A method of in vivo morphometric analyses of vertebra of the spine comprising the steps of: (a) collecting measured data indicating dimensions of multiple vertebrae; (b) measuring the height of at least two vertebrae in the measured data; (c) mathematically combining the measured heights to produce a measured index; (d) geometrically scaling reference data of spine representative of a healthy individual according to the measured index to produce scaled reference data; (e) superimposing the scaled reference data over the measured data to define at least one analyses zone; (f) identifying a morphometric fiducial point with respect to the analyses zone and the measured data of a vertebrae; and (g) measuring a distance between the fiducial point and one other fiducial point as a morphometric measure of the vertebrae.
Claim 19
Dependent Claim
18 words
The method of claim 15 wherein step (e) provides a visual display to the user of the superpositioning.
Claim 20
Independent Claim
99 words
A method of in vivo morphometric analyses of vertebra of the spine comprising the steps of: (a) collecting measured data indicating dimensions of multiple vertebrae; (b) displaying an image of the measured data; (c) manually identifying at least one analyses zone with respect to the image and the measured data; (d) analyzing the measured data with an electronic computer to identify a morphometric fiducial point with respect to the analyses zone and the measured data of a vertebrae; and (e) measuring the distance between the fiducial point and a second fiducial point as a morphometric measure of the spine.
Claim 21
Independent Claim
99 words
A method of in vivo morphometric analyses of vertebra of the spine comprising the steps of: (a) collecting measured data indicating dimensions of multiple vertebrae; (b) displaying an image of the measured data; (c) manually identifying at least one analyses zone with respect to the image and the measured data; (d) analyzing the measured data with an electronic computer to identify a morphometric fiducial point with respect to the analyses zone and the measured data of a vertebrae; and (e) measuring the distance between the fiducial point and a second fiducial point as a morphometric measure of the spine.
Claim 22
Dependent Claim
21 words
The method of claim 17 wherein the analyses zone is identified by a line positioned in the intervertebral space between vertebrae.
Claim 23
Dependent Claim
18 words
The method of claim 17 wherein the analyses zone is identified by two points placed on the image.
Claim 24
Dependent Claim
21 words
The method of claim 17 wherein the analyses zone is identified by a line positioned at the endplate of the vertebra.
Claim 25
Independent Claim
158 words
An apparatus for in vivo morphometric analyses of vertebra of the spine comprising: (a) a radiation imager collecting measured data indicating dimensions of multiple vertebrae; (b) an electronic computer receiving the measured data and operating according to a stored program to: (i) measure the height of at least two vertebrae in the measured data; (ii) combine the measured heights to produce a measured index; (iii) geometrically scale reference data of spine representative of a healthy individual according to the measured index to produce scaled reference data; (iv) superimpose the scaled reference data over the measured data to define at least one analyses zone; (v) identify a morphometric fiducial point with respect to the analyses zone and the measured data of a vertebrae; and (vi) measure the distance between the fiducial point and a second fiducial point as a morphometric measure of the spine; (c) a display communicating with the computer to display the morphometric measure to an operator.
Claim 26
Independent Claim
158 words
An apparatus for in vivo morphometric analyses of vertebra of the spine comprising: (a) a radiation imager collecting measured data indicating dimensions of multiple vertebrae; (b) an electronic computer receiving the measured data and operating according to a stored program to: (i) measure the height of at least two vertebrae in the measured data; (ii) combine the measured heights to produce a measured index; (iii) geometrically scale reference data of spine representative of a healthy individual according to the measured index to produce scaled reference data; (iv) superimpose the scaled reference data over the measured data to define at least one analyses zone; (v) identify a morphometric fiducial point with respect to the analyses zone and the measured data of a vertebrae; and (vi) measure the distance between the fiducial point and a second fiducial point as a morphometric measure of the spine; (c) a display communicating with the computer to display the morphometric measure to an operator.
Claim 27
Dependent Claim
22 words
The apparatus of claim 15 wherein the electronic computer further displays an image of the superimposed reference data and the measured data.
Claim 28
Independent Claim
136 words
An apparatus for in vivo morphometric analyses of vertebra of the spine comprising: (a) a radiation imager collecting measured data indicating dimensions of multiple vertebrae; (b) an electronic computer receiving the measured data and operating according to a stored program to: (i) collect measured data indicating dimensions of multiple vertebrae; (ii) display an image of the measured data; (iii) receive operator input to manually identify at least one analyses zone with respect to the image and the measured data; (iv) analyze the measured data to identify a morphometric fiducial point with respect to the analyses zone and the measured data; and (v) measure the distance between the fiducial point and a second fiducial point as a morphometric measure of the spine; (c) a display communicating with the computer to display the morphometric measure to an operator.
Claim 29
Independent Claim
136 words
An apparatus for in vivo morphometric analyses of vertebra of the spine comprising: (a) a radiation imager collecting measured data indicating dimensions of multiple vertebrae; (b) an electronic computer receiving the measured data and operating according to a stored program to: (i) collect measured data indicating dimensions of multiple vertebrae; (ii) display an image of the measured data; (iii) receive operator input to manually identify at least one analyses zone with respect to the image and the measured data; (iv) analyze the measured data to identify a morphometric fiducial point with respect to the analyses zone and the measured data; and (v) measure the distance between the fiducial point and a second fiducial point as a morphometric measure of the spine; (c) a display communicating with the computer to display the morphometric measure to an operator.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-11-19 | 2000-05-20 | 2000-11-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-11-19 | 2004-05-20 | 2004-11-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-11-19 | 2008-05-20 | 2008-11-19 | $7700.00 | Window Closed / Lapsed |