Patent US5569442A successfully refreshed from Google Patents.
US5569442A
Expired / Lapsed
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Reactive tricalcium phosphate compositions and uses
Assignee: KNC NOR Acquisition Sub Inc
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Filing: 1994-11-04
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Granted: 1996-10-29
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Expires: 2014-11-04
Abstract
Abstract Methods for producing a room temperature stable, phase pure alpha -C3P product, and compositions derived therefrom, are provided. In the subject method, a tricalcium phosphate source is heated to a temperature sufficient to convert substantially all of said tricalcium phosphate source to a substantially phase pure alpha -C3P product. The temperature of the resultant product is rapidly cooled to a temperature below about 700 DEG C., resulting in a room temperature stable, reactive alpha -C3P product. The resultant alpha -C3P product may be milled to provide an alpha -C3P composition which may find use in the preparation of calcium phosphate cements.
Inventors
- 👤 Mark Fulmer
- 👤 Brent R. Constantz
- 👤 Ira C. Ison
- 👤 Bryan M. Barr
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 22:46
CPC Classifications
C; C01; C01B; C01B25/00; C01B25/16; C01B25/26; C01B25/32; A; A61; A61L; A61L24/00; A61L24/02; A61L27/00; A61L27/02; A61L27/12; C01B25/321; C04; C04B; C04B12/00; C04B12/02; C04B12/025; C04B28/00; C04B28/34; C04B28/344; C04B28/346; A61F; A61F2310/00; A61F2310/00005; A61F2310/00179; A61F2310/00293; A61L2430/00; A61L2430/38; C04B2111/00; C04B2111/00474; C04B2111/00836
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
69 words
A method of preparing an α-C 3 P product comprising: heating a tricalcium phosphate source to a first temperature sufficient to cause a substantially uniform transition to phase pure α-C 3 P; and rapidly cooling said phase pure α-C 3 P to a second temperature below about 700° C. in less than about 10 min.; whereby a room temperature stable, substantially phase pure α-C 3 P product is produced.
Claim 2
Independent Claim
69 words
A method of preparing an α-C 3 P product comprising: heating a tricalcium phosphate source to a first temperature sufficient to cause a substantially uniform transition to phase pure α-C 3 P; and rapidly cooling said phase pure α-C 3 P to a second temperature below about 700° C. in less than about 10 min.; whereby a room temperature stable, substantially phase pure α-C 3 P product is produced.
Claim 3
Dependent Claim
23 words
A method according to claim 1, wherein said rapid cooling step comprises temperature quenching by mechanically breaking-up said phase pure α-C 3 P.
Claim 4
Dependent Claim
31 words
A method according to claim 1, wherein said rapid cooling step comprises temperature quenching by placing said phase pure α-C 3 P in a forced flow of cool gas or liquid.
Claim 5
Independent Claim
66 words
A method of preparing an α-C 3 P product comprising: heating a tricalcium phosphate source to a first temperature sufficient to cause a substantially uniform transition to phase pure α-C 3 P; and temperature quenching said substantially phase pure α-C 3 P to a second temperature between about 0° C. and 200° C.; whereby a room temperature stable, substantially phase pure α-C 3 P is produced.
Claim 6
Independent Claim
66 words
A method of preparing an α-C 3 P product comprising: heating a tricalcium phosphate source to a first temperature sufficient to cause a substantially uniform transition to phase pure α-C 3 P; and temperature quenching said substantially phase pure α-C 3 P to a second temperature between about 0° C. and 200° C.; whereby a room temperature stable, substantially phase pure α-C 3 P is produced.
Claim 7
Dependent Claim
38 words
A method according to claim 4, wherein said tricalcium phosphate source is prepared by combining stoichiometric amounts of CaHPO 4 and CaCO 3 in an aqueous reaction volume for a time sufficient to produce said tricalcium phosphate source.
Claim 8
Dependent Claim
19 words
A method according to claim 4, wherein said temperature quenching comprises mechanically breaking-up said phase pure α-C 3 P.
Claim 9
Dependent Claim
27 words
A method according to claim 4, wherein said temperature quenching comprises placing said phase pure α-C 3 P in a forced flow of cool gas or liquid.
Claim 10
Dependent Claim
20 words
A room temperature stable, substantially phase pure α-C 3 P product produced in accordance with the method of claim 4.
Claim 11
Dependent Claim
31 words
A particulate composition of substantially phase pure α-C 3 P product produced in accordance with the method of claim 4, wherein the particle size ranges from about 1.0 to 180 μm.
Claim 12
Independent Claim
82 words
A method of preparing an α-C 3 P product comprising: heating a tricalcium phosphate source to a first temperature ranging from about 1200° C. to 1700° C. to cause a substantially uniform transition to phase pure α-C 3 P; and temperature quenching said substantially phase pure α-C 3 P to a second temperature between about 0° C. and 200° C. over a period of less than about 45 min.; whereby a room temperature stable, substantially phase pure α-C 3 P is produced.
Claim 13
Independent Claim
82 words
A method of preparing an α-C 3 P product comprising: heating a tricalcium phosphate source to a first temperature ranging from about 1200° C. to 1700° C. to cause a substantially uniform transition to phase pure α-C 3 P; and temperature quenching said substantially phase pure α-C 3 P to a second temperature between about 0° C. and 200° C. over a period of less than about 45 min.; whereby a room temperature stable, substantially phase pure α-C 3 P is produced.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-10-29 | 2000-04-29 | 2000-10-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-10-29 | 2004-04-29 | 2004-10-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-10-29 | 2008-04-29 | 2008-10-29 | $7700.00 | Window Closed / Lapsed |