US5565210A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Bioabsorbable wound implant materials
Assignee: Ethicon Inc
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Filing: 1995-04-05
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Granted: 1996-10-15
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Expires: 2015-04-05
Abstract
Abstract Heteromorphic sponges are described which have matrix structures with oriented substructures added to facilitate cellular invasion. A sponge may be used as a wound implant by cutting it to the shape of a wound bed and placing therein. The matrix structure provides conduits which assist invasion of the sponge by cells which degrade the sponge and lay down new tissue to replace it. The incorporation of active agents in the matrix and/or substructures enhances wound healing.
Inventors
- 👤 Arthur L. Rosenthal
- 👤 Nicholas D. Light
- 👤 Paul W. Watt
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 18:50
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/58; A61F; A61F13/00; A61F13/15; A61L15/00; A61L15/16; A61L15/22; A61L15/225; A61L15/32; A61L15/325; A61L15/42; A61L15/425; A61L15/44; A61L15/54; A61L27/14; A61L27/22; A61L27/227; A61L27/24; A61L27/40; A61L27/44; A61L27/48; A61L27/54; A61L27/56; A61F2013/00089; A61F2013/00217; A61F2013/00221; A61F2310/00; A61F2310/00005; A61F2310/00365
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
57 words
A bioabsorbable heteromorphic sponge for use in promoting wound healing, comprising a matrix structure of sponge and at least one macroscopic substructure embedded therein, wherein the matrix and the substructure are formed of bioabsorbable materials and the substructure is anisotropic, thereby defining a scaffolding providing channels in preferred directions for cellular and tissue ingrowth into the sponge.
Claim 2
Dependent Claim
57 words
A bioabsorbable heteromorphic sponge for use in promoting wound healing, comprising a matrix structure of sponge and at least one macroscopic substructure embedded therein, wherein the matrix and the substructure are formed of bioabsorbable materials and the substructure is anisotropic, thereby defining a scaffolding providing channels in preferred directions for cellular and tissue ingrowth into the sponge.
Claim 3
Dependent Claim
28 words
The bioabsorbable heteromorphic sponges of claim 1, wherein the substructure is selected from the group consisting of films, flaked or broken films fibres, fibre bundles and mixtures thereof.
Claim 4
Dependent Claim
21 words
The bioabsorbable heteromorphic sponge of claim 1, wherein the substructure comprises films or flaked or broken films defining a laminated structure.
Claim 5
Dependent Claim
16 words
The bioabsorbable heteromorphic sponge of claim 1, wherein the substructure defines linear channels in the sponge.
Claim 6
Dependent Claim
28 words
The bioabsorbable heteromorphic sponge of claim 1, wherein at least 75% of the substructure is oriented within 30 degrees of a mean direction of orientation of the substructure.
Claim 7
Dependent Claim
28 words
The bioabsorbable heteromorphic sponge of claim 1, wherein at least 75% of the substructure is oriented within 20 degrees of a mean direction of orientation of the substructure.
Claim 8
Dependent Claim
25 words
The bioabsorbable heteromorphic sponge of claim 1, further comprising a therapeutically effective amount of at least one material which is active in aiding wound healing.
Claim 9
Dependent Claim
20 words
The bioabsorbable heteromorphic sponge of claim 1 wherein the matrix structure and at least one substructure have different chemical compositions.
Claim 10
Dependent Claim
23 words
The bioabsorbable heteromorphic sponge of claim 1 wherein the material of the matrix structure is the same as the material of the substructure.
Claim 11
Dependent Claim
22 words
The bioabsorbable heteromorphic sponge of claim 1 wherein the material of the matrix structure is different from the material of the substructure.
Claim 12
Dependent Claim
16 words
The bioabsorbable heteromorphic sponge of claim 10 wherein the material of the matrix structure comprises collagen.
Claim 13
Dependent Claim
22 words
The bioabsorbable heteromorphic sponge of claim 1 wherein the material of the matrix structure and the material of the substructure comprises collagen.
Claim 14
Dependent Claim
24 words
The bioabsorbable heteromorphic sponge of claim 1 wherein the substructure comprises planar films which provide a plurality of planes for cellular or tissue ingrowth.
Claim 15
Dependent Claim
26 words
The bioabsorbable heteromorphic sponge of claim 1 wherein the substructure comprises flaked or broken films which provide a plurality of planes for cellular or tissue ingrowth.
Claim 16
Dependent Claim
46 words
The bioabsorbable heteromorphic sponge of claim 1 wherein the bioabsorbable materials of the matrix structure and substructure are chosen from the group consisting of: collagen, elastin, fibronectin, laminim, tenascin, hyaluronic acid, chondroitin sulphate, dermatan sulphate, fibrin, dextran, heparin sulphate, vitronectin, oxidized regenerated cellulose and mixtures thereof.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-10-15 | 2000-04-15 | 2000-10-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-10-15 | 2004-04-15 | 2004-10-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-10-15 | 2008-04-15 | 2008-10-15 | $7700.00 | Window Closed / Lapsed |