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US5522894A Expired / Lapsed US ⏱️ 0.0 years remaining

Bone replacement material made of absorbable beads

Assignee: THURGAUER KANTONALBANK A Corp CHARTERED IN AND EXISTING UNDER LAWS OF SWITZERLAND THAT MAINTAINS ITS PRINCIPAL OFFICES AT
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Filing: 1993-03-29
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Granted: 1996-06-04
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Expires: 2013-03-29
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Abstract

Abstract The invention relates to a bone replacement material consisting of a three-dimensional supporting framework of elementary bodies connected to one another and surrounding defined spaces, and a coating mass of fillers (based on strong calcium compounds) and a binding substance (matrix). The binding substance and the fillers are absorbable and the fillers are highly porous spherical particles with a diameter of between 15 and 50 μm and a pore volume of between 50 to 80%, to which some filamentous material can be added. The bone replacement material of the invention is suited to produce coatings for prostheses, thus serving as an anchoring part for prostheses. It can also be used as a complete implant.

Inventors

  • 👤 Klaus Draenert

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-03 20:08
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/30; A61F2/30767; A61C; A61C8/00; A61C8/0012; A61C8/0013; A61F2/28; A61L; A61L27/00; A61L27/28; A61L27/40; A61L27/44; A61L27/46; A61L27/50; A61L27/56; A61L27/58; A61L31/00; A61L31/08; A61L31/14; A61L31/148; A61F2002/2835; A61F2002/2839; A61F2002/30001; A61F2002/30003; A61F2002/30004; A61F2002/30014; A61F2002/3006; A61F2002/30062; A61F2002/30108; A61F2002/30199; A61F2002/30242; A61F2002/30667; A61F2002/30677; A61F2/3094; A61F2/30942; A61F2002/30957; A61F2210/00; A61F2210/0004; A61F2230/00; A61F2230/0063; A61F2230/0071; A61F2250/00; A61F2250/0014; A61F2250/0018; A61F2250/0058; A61F2250/0067; A61L2430/00; A61L2430/02

Claims Analysis

Total Claims: 24
Claim 1
Independent Claim 75 words
Bone replacement material comprising a three-dimensional supporting structure, the supporting structure comprising a plurality of elementary bodies, each elementary body being made of an absorbable substance and being substantially spherical, the size of the bodies being at least 200 μm, the elementary bodies being held together such that each elementary body is held in rigid contact with at least three adjacent elementary bodies to define enclosed spaces therebetween which provide for bone ingrowth and penetration.
Claim 2
Dependent Claim 75 words
Bone replacement material comprising a three-dimensional supporting structure, the supporting structure comprising a plurality of elementary bodies, each elementary body being made of an absorbable substance and being substantially spherical, the size of the bodies being at least 200 μm, the elementary bodies being held together such that each elementary body is held in rigid contact with at least three adjacent elementary bodies to define enclosed spaces therebetween which provide for bone ingrowth and penetration.
Claim 3
Dependent Claim 26 words
Bone replacement material according to claim 1 wherein each elementary body is adjoined to each adjacent elementary body to form a three-dimensional pack of maximum density.
Claim 4
Dependent Claim 29 words
Bone replacement material according to claim 1 wherein said elementary bodies are made of a material selected from the group consisting of tricalcium phosphate, apatite, collagen and a polypeptide.
Claim 5
Dependent Claim 23 words
Bone replacement material according to claim 1 wherein the size of said substantially spherical elementary bodies is between 200 μm and 3,000 μm.
Claim 6
Dependent Claim 70 words
Bone replacement material according to claim 4 wherein the elementary bodies include a first set of elementary bodies having a diameter between 200 and 1,000 μm with a mean diameter of 500 μm and a second set of elementary bodies having a diameter between 800 and 3,000 μm with a mean diameter of 1,000 μm, the first set of elementary bodies being mixed with the second set of elementary bodies.
Claim 7
Dependent Claim 39 words
Bone replacement material according to claim 4 wherein a first set of elementary bodies with a diameter between 200 and 1,000 μm are mixed with a second set of elementary bodies with a diameter between 800 and 3,000 μm.
Claim 8
Dependent Claim 23 words
Bone replacement material according to claim 1 wherein said elementary bodies form a three-dimensional framework or network which is rigidly braced by struts.
Claim 9
Dependent Claim 28 words
Bone replacement material according to claim 1 wherein the material contains admixtures selected from the group consisting of hemostatic agents, bone-building substances, antibiotics, vasoactive substances and bone-active hormones.
Claim 10
Dependent Claim 18 words
Bone replacement material according to claim 8 further containing an antibiotic effective in the treatment of bone infections.
Claim 11
Dependent Claim 23 words
Bone replacement material according to claim 8 wherein the vaso-active substance is selected from the group consisting of noradrenalin and a noradrenalin derivative.
Claim 12
Dependent Claim 14 words
Bone replacement material according to claim 8 further containing calcitonin as the bone-active hormone.
Claim 13
Dependent Claim 27 words
Bone replacement material according to claim 1 wherein the material takes the form of a socket, a cylinder, a flat coil spring, a sphere or a sponge.
Claim 14
Independent Claim 89 words
A method of replacing bone material comprising: providing a bone replacement material comprising a three-dimensional supporting structure having a plurality of elementary bodies, said elementary bodies being made of an absorbable substance and being substantially spherical, the size of the bodies being at least 200 μm, the elementary bodies being held together such that each elementary body is held in rigid contact with at least three adjacent elementary bodies to define enclosed spaces which for provide bone ingrowth and penetration; and replacing bone material with the bone replacement material.
Claim 15
Independent Claim 89 words
A method of replacing bone material comprising: providing a bone replacement material comprising a three-dimensional supporting structure having a plurality of elementary bodies, said elementary bodies being made of an absorbable substance and being substantially spherical, the size of the bodies being at least 200 μm, the elementary bodies being held together such that each elementary body is held in rigid contact with at least three adjacent elementary bodies to define enclosed spaces which for provide bone ingrowth and penetration; and replacing bone material with the bone replacement material.
Claim 16
Dependent Claim 17 words
Bone replacement material according to claim 7 wherein the elementary bodies of the three-dimensional network are interlaced.
Claim 17
Independent Claim 84 words
A method of coating a bone or joint implant to treat bone gaps, said method comprising: providing a bone replacement material comprising a three-dimensional supporting structure having elementary bodies, said elementary bodies being made of an absorbable substance, being substantially spherical, and being held together so that elementary body is held in rigid contact with at least three adjacent elementary bodies to define enclosed spaces which provide for bone ingrowth and penetration; and coating the bone or joint implant with the bone replacement material.
Claim 18
Independent Claim 84 words
A method of coating a bone or joint implant to treat bone gaps, said method comprising: providing a bone replacement material comprising a three-dimensional supporting structure having elementary bodies, said elementary bodies being made of an absorbable substance, being substantially spherical, and being held together so that elementary body is held in rigid contact with at least three adjacent elementary bodies to define enclosed spaces which provide for bone ingrowth and penetration; and coating the bone or joint implant with the bone replacement material.
Claim 19
Independent Claim 83 words
A method of replacing a joint comprising: providing a bone replacement material in the form of a prosthesis, the bone replacement material comprising a three-dimensional supporting structure having elementary bodies, said elementary bodies being made of an absorbable substance, being substantially spherical, and being held together so that each elementary body is held in rigid contact with at least three adjacent elementary bodies to define enclosed spaces which provide for bone ingrowth and penetration; and replacing the joint with the bone replacement material.
Claim 20
Independent Claim 83 words
A method of replacing a joint comprising: providing a bone replacement material in the form of a prosthesis, the bone replacement material comprising a three-dimensional supporting structure having elementary bodies, said elementary bodies being made of an absorbable substance, being substantially spherical, and being held together so that each elementary body is held in rigid contact with at least three adjacent elementary bodies to define enclosed spaces which provide for bone ingrowth and penetration; and replacing the joint with the bone replacement material.
Claim 21
Independent Claim 87 words
A method of anchoring bone screws using a bone dowel comprising: providing a bone replacement material in the form of a bone dowel, the bone replacement material comprising a three-dimensional supporting structure having elementary bodies, said elementary bodies being made of an absorbable substance, being substantially spherical, and being held together so that each elementary body is held in rigid contact with at least three adjacent elementary bodies to define enclosed spaces which provide for bone ingrowth and penetration; and anchoring bone screws using the bone dowel.
Claim 22
Independent Claim 87 words
A method of anchoring bone screws using a bone dowel comprising: providing a bone replacement material in the form of a bone dowel, the bone replacement material comprising a three-dimensional supporting structure having elementary bodies, said elementary bodies being made of an absorbable substance, being substantially spherical, and being held together so that each elementary body is held in rigid contact with at least three adjacent elementary bodies to define enclosed spaces which provide for bone ingrowth and penetration; and anchoring bone screws using the bone dowel.
Claim 23
Independent Claim 83 words
A method of closing off medullary cavities comprising: providing a bone replacement material in the form of a medullary cavity closure comprising a three-dimensional supporting structure having elementary bodies, said elementary bodies being made of an absorbable substance, being substantially spherical, and being held together so that each elementary body is held in rigid contact with at least three adjacent elementary bodies to define enclosed spaces which provide for bone ingrowth and penetration; and closing the medullary cavity using the bone replacement material.
Claim 24
Independent Claim 83 words
A method of closing off medullary cavities comprising: providing a bone replacement material in the form of a medullary cavity closure comprising a three-dimensional supporting structure having elementary bodies, said elementary bodies being made of an absorbable substance, being substantially spherical, and being held together so that each elementary body is held in rigid contact with at least three adjacent elementary bodies to define enclosed spaces which provide for bone ingrowth and penetration; and closing the medullary cavity using the bone replacement material.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1999-06-04 1999-12-04 2000-06-04 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2003-06-04 2003-12-04 2004-06-04 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2007-06-04 2007-12-04 2008-06-04 $7700.00 Window Closed / Lapsed

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