Patent US928866A successfully refreshed from Google Patents.
Patent US5503157A successfully refreshed from Google Patents.
US5503157A
Expired / Lapsed
US
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System for detection of electrical bioimpedance signals
Assignee: HEMO SAPIENS Inc
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Filing: 1995-03-17
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Granted: 1996-04-02
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Expires: 2015-03-17
Abstract
Abstract A system and method for detection of electrical bioimpedance signals in a human or animal body segment. The system comprises a constant current generator for generating a periodic high frequency current output across a body segment in response to a periodic control input signal, a controller for generating a periodic control output signal to control operation of the current generator and an electrical bioimpedance detector for detecting a voltage generated across the body segment by the flow of current in the segment. The electrical bioimpedance detector generates an output signal indicative of bioimpedance in the body segment. The periodic generation of a current across a body segment alleviates the potentially detrimental effects of a continuous current on body segment tissue and reduces interference with the function of certain pacemakers.
Inventors
- 👤 Bohumir Sramek
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 23:05
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/02; A61B5/026; A61B5/0295; A61B5/72; A61B5/7235; A61B5/7239
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
300 words
A system for determining or measuring fluid content or fluid flow in a human or animal body segment, comprising: (a) a current generator means for generating a periodic high frequency current output in response to a periodic control signal, the current generator means comprising: (i) a first and a second output terminal for carrying the current output, wherein the first and the second output terminal means are adapted to be electrically connectable to a first and a second portion of the human or animal body segment, respectively; and (ii) an input terminal means for receiving the control signal; (b) a controller means for generating the periodic control signal to control operation of the current generator means, the controller means including an output terminal for carrying the control signal, wherein the output terminal of the controller means is electrically connected to the input terminal means of the current generator means; and (c) an electrical bioimpedance detector means for detecting a voltage between the first and the second portion of the human or animal body segment caused by the current output of the current generator means flowing between the first and the second portion of the human or animal body segment, and for generating an output signal in response, wherein the output signal is indicative of impedance in the human or animal body segment between the first and the second portion, the bioimpedance detector means comprising: (i) a first and a second input terminal means for detecting said voltage, wherein the first and the second input terminal means of the bioimpedance detector means are adapted to be electrically connectable to the human or animal body segment proximate the first and second output terminal means of the current generator means, respectively; and (ii) an output terminal means for carrying the detector's output signal.
Claim 2
Independent Claim
300 words
A system for determining or measuring fluid content or fluid flow in a human or animal body segment, comprising: (a) a current generator means for generating a periodic high frequency current output in response to a periodic control signal, the current generator means comprising: (i) a first and a second output terminal for carrying the current output, wherein the first and the second output terminal means are adapted to be electrically connectable to a first and a second portion of the human or animal body segment, respectively; and (ii) an input terminal means for receiving the control signal; (b) a controller means for generating the periodic control signal to control operation of the current generator means, the controller means including an output terminal for carrying the control signal, wherein the output terminal of the controller means is electrically connected to the input terminal means of the current generator means; and (c) an electrical bioimpedance detector means for detecting a voltage between the first and the second portion of the human or animal body segment caused by the current output of the current generator means flowing between the first and the second portion of the human or animal body segment, and for generating an output signal in response, wherein the output signal is indicative of impedance in the human or animal body segment between the first and the second portion, the bioimpedance detector means comprising: (i) a first and a second input terminal means for detecting said voltage, wherein the first and the second input terminal means of the bioimpedance detector means are adapted to be electrically connectable to the human or animal body segment proximate the first and second output terminal means of the current generator means, respectively; and (ii) an output terminal means for carrying the detector's output signal.
Claim 3
Dependent Claim
65 words
The system of claim 1 wherein the bioimpedance detector means further comprises a sensing circuit means, coupled to the input terminal means of the bioimpedance detector means, for receiving said voltage and generating an output signal having a magnitude that changes in accordance with the content or flow of fluids in the human or animal body segment between the first and second body segment portions.
Claim 4
Dependent Claim
99 words
The system of claim 2 wherein the bioimpedance detector further comprises: (a) a third input terminal means electrically connected to the output terminal means of the controller means, whereby the central signal of the controller means is simultaneously received by both the current generator means and the bioimpedance detector means; and (b) a synchronizer means, coupled to the sensing circuit means, for controlling the operation of the sensing circuit means in response to the control signal from the controller means, whereby the sensing circuit means periodically detects said voltage in synchrony with the operation of the current generator means.
Claim 5
Dependent Claim
23 words
The system of claim 3 wherein the synchronizer means comprises an electrically controlled switch responsive to the control signal from the controller means.
Claim 6
Dependent Claim
78 words
The system of claim 2 wherein the sensing circuit means comprises: (a) an amplifier means, coupled to the input terminal means of the bioimpedance detector means, for receiving and amplifying said voltage as an output signal; and (b) an analog-to-digital converter means, responsive to the output signal of the amplifier means, for converting the output signal to a digital output signal representative of impedance in the human or animal body segment between the first and the second portions.
Claim 7
Dependent Claim
62 words
The system of claim 5 wherein the sensing circuit means further comprises a digital differentiator means, responsive to the digital output signal of the analog-to-digital converter means, for generating data representing a differentiated voltage output signal having a magnitude proportional to a rate of change of electrical bioimpedance in the human or animal body segment between the first and the second portions.
Claim 8
Dependent Claim
29 words
The system of claim 5 wherein the sensing circuit means further comprises a processor means, responsive to the digital output signal of the analog-to-digital converter means, for processing data.
Claim 9
Dependent Claim
47 words
The system of claim 5 wherein the bioimpedance detector means further comprises a delay circuit means, connected in series between the amplifier means and the analog-to-digital converter means, for sampling and holding the output signal of the amplifier means for later retrieval by the analog-to-digital converter means.
Claim 10
Dependent Claim
88 words
The system of claim 1 wherein the current generator means further comprises: (a) a current source means for generating a high frequency current output, the current source means being coupled across the output terminal means of the current generator means; and (b) an electrically controlled switch coupled to the current source means, for regulating the operation of the current source means in response to the control signal from the controller means, whereby the current source means generates the high frequency current output only when the switch is closed.
Claim 11
Dependent Claim
30 words
The system of claim 1 wherein the controller means further comprises a timing circuit means, coupled to the output terminal of the controller means, for generating the periodic control signal.
Claim 12
Dependent Claim
13 words
The system of claim 10 wherein the timing circuit means is a microprocessor.
Claim 13
Independent Claim
142 words
A method of determining or measuring fluid content or fluid flow in a human or animal body segment, comprising: (a) periodically generating a high frequency current; (b) applying the current to a first and a second portion of the human or animal body segment; (c) detecting a voltage between a third and a fourth portion of the human or animal body segment, wherein the third and the fourth portions are located proximate the first and the second portion of the human or animal body segment, and the detected voltage is caused by impedance to the current flow in the human or animal body segment between the third and the fourth portions; and (d) generating a signal based on the detected voltage, wherein the signal is indicative of impedance in the human or animal body segment between the third and the fourth portions.
Claim 14
Independent Claim
142 words
A method of determining or measuring fluid content or fluid flow in a human or animal body segment, comprising: (a) periodically generating a high frequency current; (b) applying the current to a first and a second portion of the human or animal body segment; (c) detecting a voltage between a third and a fourth portion of the human or animal body segment, wherein the third and the fourth portions are located proximate the first and the second portion of the human or animal body segment, and the detected voltage is caused by impedance to the current flow in the human or animal body segment between the third and the fourth portions; and (d) generating a signal based on the detected voltage, wherein the signal is indicative of impedance in the human or animal body segment between the third and the fourth portions.
Claim 15
Dependent Claim
50 words
The method of claim 12 wherein the step of detecting further comprises: (a) receiving and amplifying said voltage to generate an amplified signal; and (b) converting the amplified signal to a digital signal representative of impedance in the human or animal body segment between the third and the fourth portions.
Claim 16
Dependent Claim
48 words
The method of claim 13 further comprising the step of digitally differentiating the digital signal to generate a differentiated voltage output signal having a magnitude proportional to a rate of change of electrical bioimpedance in the human or animal body segment between the third and the fourth portions
Claim 17
Dependent Claim
24 words
The method of claim 12 wherein the step of detecting comprises periodically detecting said voltage in synchrony with the periodic generation of the current.
Claim 18
Dependent Claim
30 words
The method of claim 12 wherein the step of detecting further comprises sampling and holding the output signal of the amplifier for later retrieval and conversion to a digital signal.
References Cited (Backward Citations)
US4450527A
Cited
US4953556A
Cited
US4836214A
Cited
US4870578A
Cited
US4807638A
Cited
US5309917A
Cited
US5423326A
Cited
US5385576A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-04-02 | 1999-10-02 | 2000-04-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-04-02 | 2003-10-02 | 2004-04-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-04-02 | 2007-10-02 | 2008-04-02 | $7700.00 | Window Closed / Lapsed |