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US5501836A
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Entrapped non-enzymatic macromolecules for chemical sensing
Assignee: HP Inc
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Filing: 1994-07-11
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Granted: 1996-03-26
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Expires: 2014-07-11
Abstract
Abstract A sensor made of porous matrix or sol-gel glass and non-enzymatic macromolecular polymer immobilized in the sol-gel glass. The macromolecule is physically entangled or otherwise trapped, and does not leach regardless of exposure to elevated temperature and pressure. Surface effects are minimized since the there is no chemical bond between macromolecules and sol-gel glass. Indicator molecules may be attached to the macromolecular polymer either before or after the macromolecule is incorporated into the porous matrix.
Inventors
- 👤 Joel Myerson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 19:45
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/543; G01N33/551; G01N33/552; G01N31/00; G01N31/22; G01N33/54366; G01N33/54373
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
58 words
A sensor element useful in making optical measurement wherein the sensor element comprises: a sol-gel glass; an immobilized macromolecule integrated within the sol-gel glass wherein the immobilized macromolecule is non-covalently bonded to the sol-gel and wherein it includes a chemically sensitive indicator material; and wherein the resulting sensor element performs at temperatures up to approximately 121 degrees C.
Claim 2
Dependent Claim
58 words
A sensor element useful in making optical measurement wherein the sensor element comprises: a sol-gel glass; an immobilized macromolecule integrated within the sol-gel glass wherein the immobilized macromolecule is non-covalently bonded to the sol-gel and wherein it includes a chemically sensitive indicator material; and wherein the resulting sensor element performs at temperatures up to approximately 121 degrees C.
Claim 3
Dependent Claim
25 words
A sensor element as in claim 1 wherein the immobilized macromolecule is selected from a group consisting of: polyvinyl amine, polyallylamine, polyacrylic acid, polyvinyl alcohol.
Claim 4
Dependent Claim
14 words
A sensor element as in claim 1 wherein the immobilized macromolecule is a polypeptide.
Claim 5
Dependent Claim
28 words
A sensor element as in claim 1 wherein the immobilized macromolecule is comprised of a plurality of polymer types present in a pre-determined ratio in the sol-gel glass.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-03-26 | 1999-09-25 | 2000-03-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-03-26 | 2003-09-25 | 2004-03-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-03-26 | 2007-09-25 | 2008-03-26 | $7700.00 | Window Closed / Lapsed |