Patent US5501701A successfully refreshed from Google Patents.
US5501701A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pacemaker with vasovagal syncope detection and therapy
Assignee: Medtronic Inc
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Filing: 1994-09-20
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Granted: 1996-03-26
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Expires: 2014-09-20
Abstract
Abstract A method and apparatus for cardiac pacing, in which pacing pulses are provided at an increased rate in response to a detected rapid drop in heart rate. A rapid drop is detected in response to heart rate falling from a persistent rate above a first threshold rate to a stable rate below a second threshold rate. If spontaneous depolarizations are detected while pacing at the increased rate, pacing at the increased rate is terminated.
Inventors
- 👤 H. Toby Markowitz
- 👤 Michael F. Hess
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 12:50
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/18; A61N1/32; A61N1/36; A61N1/362; A61N1/365; A61N1/36514
Claims Analysis
Total Claims: 34
Claim 1
Independent Claim
84 words
A cardiac pacer comprising: means for detecting depolarizations of a heart and generating signals therefrom; means for determining an intrinsic heart rate connected to receive said signals from such detected depolarization; pulse generating means for delivering cardiac pacing pulses at a first pacing rate; means for defining first and second threshold heart rates; drop detecting means for detecting a rapid drop in spontaneous heart depolarization rate from a rate above said first threshold heart rate to a rate below said second threshold heart rate.
Claim 2
Dependent Claim
84 words
A cardiac pacer comprising: means for detecting depolarizations of a heart and generating signals therefrom; means for determining an intrinsic heart rate connected to receive said signals from such detected depolarization; pulse generating means for delivering cardiac pacing pulses at a first pacing rate; means for defining first and second threshold heart rates; drop detecting means for detecting a rapid drop in spontaneous heart depolarization rate from a rate above said first threshold heart rate to a rate below said second threshold heart rate.
Claim 3
Dependent Claim
156 words
A cardiac pacer comprising: means for detecting depolarizations of a heart; means for determining an intrinsic heart rate from such detected depolarization; pulse generating means for delivering cardiac pacing pulses at a first pacing rate; means for defining first and second threshold heart rates; drop detecting means for detecting a rapid drop in spontaneous heart depolarization rate from a rate above said first threshold heart rate to an rate below said second threshold heart rate and comprising means for detecting a persistent heart depolarization rate above said first threshold heart rate and means for detecting a rapid drop in spontaneous heart depolarization rate from said persistent heart rate above said first threshold heart rate to a rate below said second threshold heart rate. means responsive to said detected rapid drop in spontaneous heart depolarization rate for causing said pulse generator means to deliver pacing pulses at a second pacing rate higher than said first pacing rate.
Claim 4
Dependent Claim
156 words
A cardiac pacer comprising: means for detecting depolarizations of a heart; means for determining an intrinsic heart rate from such detected depolarization; pulse generating means for delivering cardiac pacing pulses at a first pacing rate; means for defining first and second threshold heart rates; drop detecting means for detecting a rapid drop in spontaneous heart depolarization rate from a rate above said first threshold heart rate to an rate below said second threshold heart rate and comprising means for detecting a persistent heart depolarization rate above said first threshold heart rate and means for detecting a rapid drop in spontaneous heart depolarization rate from said persistent heart rate above said first threshold heart rate to a rate below said second threshold heart rate. means responsive to said detected rapid drop in spontaneous heart depolarization rate for causing said pulse generator means to deliver pacing pulses at a second pacing rate higher than said first pacing rate.
Claim 5
Dependent Claim
36 words
A cardiac pacer according to claim 2 wherein said means for detecting a persistent heart depolarization rate comprises means for detecting a sequence of a predetermined number of heart depolarizations above said first threshold heart rate.
Claim 6
Dependent Claim
58 words
A cardiac pacer according to claim 1 wherein said drop detecting means comprises means for detecting a stable heart depolarization rate below said second threshold heart rate and means for detecting a rapid drop in spontaneous heart depolarization rate from a rate above said first threshold heart rate to a stable rate below said second threshold heart rate.
Claim 7
Dependent Claim
41 words
A cardiac pacer according to claim 4 wherein said means for detecting a stable heart depolarization rate below said second threshold heart rate comprises means for detecting a predetermined proportion of heart depolarizations having rates less than said second threshold rate.
Claim 8
Dependent Claim
71 words
A cardiac pacer comprising: means for detecting heart depolarizations and for generating signals therefrom; means for determining an intrinsic heart rate connected to receive said signals from such detected depolarizations; pulse generating means for delivering cardiac pacing pulses at a first pacing rate; means for defining a threshold heart rate; drop detecting means for detecting a rapid drop in spontaneous heart depolarization rate from a rate above said threshold heart rate.
Claim 9
Dependent Claim
71 words
A cardiac pacer comprising: means for detecting heart depolarizations and for generating signals therefrom; means for determining an intrinsic heart rate connected to receive said signals from such detected depolarizations; pulse generating means for delivering cardiac pacing pulses at a first pacing rate; means for defining a threshold heart rate; drop detecting means for detecting a rapid drop in spontaneous heart depolarization rate from a rate above said threshold heart rate.
Claim 10
Dependent Claim
132 words
A cardiac pacer comprising: means for detecting heart depolizations; means for determining an intrinsic heart rate from such detected depolarizations; pulse generating means for delivering cardiac pacing pulses at a first pacing rate; means for defining a threshold heart rate; drop detecting means for detecting a rapid drop in spontaneous heart depolarization rate from a rate above said threshold heart rate comprising means for detecting a persistent heart depolarization rate above said threshold heart rate and means for detecting a rapid drop in spontaneous heart depolarization rate from said persistent heart depolarization rate above said threshold heart rate; means responsive to a said detected rapid drop in spontaneous heart depolarization rate for causing said pulse generator means to deliver pacing pulses at a second pacing rate higher than said first pacing rate.
Claim 11
Dependent Claim
132 words
A cardiac pacer comprising: means for detecting heart depolizations; means for determining an intrinsic heart rate from such detected depolarizations; pulse generating means for delivering cardiac pacing pulses at a first pacing rate; means for defining a threshold heart rate; drop detecting means for detecting a rapid drop in spontaneous heart depolarization rate from a rate above said threshold heart rate comprising means for detecting a persistent heart depolarization rate above said threshold heart rate and means for detecting a rapid drop in spontaneous heart depolarization rate from said persistent heart depolarization rate above said threshold heart rate; means responsive to a said detected rapid drop in spontaneous heart depolarization rate for causing said pulse generator means to deliver pacing pulses at a second pacing rate higher than said first pacing rate.
Claim 12
Dependent Claim
35 words
A cardiac pacer according to claim 7 wherein said means for detecting a persistent heart depolarization rate comprises means for detecting a sequence of a predetermined number of heart depolarizations above said threshold heart rate.
Claim 13
Dependent Claim
144 words
A cardiac pacer comprising: means for detecting heart depolarizations; pulse generating means for delivering cardiac pacing pulses at a first pacing rate; means for defining a threshold heart rate; means for detecting a rapid rate drop comprising; means for detecting a stable heart depolarization rate below said threshold heart rate, and means for detecting a rapid drop in spontaneous heart depolarization rate to a stable rate below said threshold heart rate, said means for detecting a stable heart depolarization rate below said threshold heart rate comprising means for detecting a predetermined proportion of heart depolarizations having rates less than said threshold rate to heart depolarizations having a rate greater than said threshold rate; and means for causing said pulse generating means to deliver pacing pulses at a second pacing rate, higher than said first pacing rate, responsive to a said detected rapid rate drop.
Claim 14
Dependent Claim
144 words
A cardiac pacer comprising: means for detecting heart depolarizations; pulse generating means for delivering cardiac pacing pulses at a first pacing rate; means for defining a threshold heart rate; means for detecting a rapid rate drop comprising; means for detecting a stable heart depolarization rate below said threshold heart rate, and means for detecting a rapid drop in spontaneous heart depolarization rate to a stable rate below said threshold heart rate, said means for detecting a stable heart depolarization rate below said threshold heart rate comprising means for detecting a predetermined proportion of heart depolarizations having rates less than said threshold rate to heart depolarizations having a rate greater than said threshold rate; and means for causing said pulse generating means to deliver pacing pulses at a second pacing rate, higher than said first pacing rate, responsive to a said detected rapid rate drop.
Claim 15
Dependent Claim
106 words
A cardiac pacer comprising: means for detecting heart depolarizations; pulse generating means for delivering cardiac pacing pulses at a first pacing rate; drop detecting means for detecting a rapid drop in spontaneous heart depolarization rate; means responsive to a said detected rapid drop in spontaneous heart depolarization rate for causing said pulse generator means to deliver pacing pulses at a second pacing rate instead of and higher than said first pacing rate; means responsive to detected heart depolarizations while said pulse generating means is delivering pacing pulses at said second pacing rate, for causing said pulse generating means to generate pulses at said first pacing rate.
Claim 16
Dependent Claim
106 words
A cardiac pacer comprising: means for detecting heart depolarizations; pulse generating means for delivering cardiac pacing pulses at a first pacing rate; drop detecting means for detecting a rapid drop in spontaneous heart depolarization rate; means responsive to a said detected rapid drop in spontaneous heart depolarization rate for causing said pulse generator means to deliver pacing pulses at a second pacing rate instead of and higher than said first pacing rate; means responsive to detected heart depolarizations while said pulse generating means is delivering pacing pulses at said second pacing rate, for causing said pulse generating means to generate pulses at said first pacing rate.
Claim 17
Dependent Claim
123 words
A cardiac pacer according to claim 10, wherein; said means for causing said pulse generator means to deliver pacing pulses at a second pacing rate comprises means for causing said pulse generator means to deliver pacing pulses at a second pacing rate for a defined time interval, and wherein said pacer further comprises: means for causing said pulse generating means to deliver pacing pulses at a sequence of pacing rates gradually decreasing from said second pacing rate to said first pacing rate, after said defined time interval; and means responsive to detected heart depolarizations while said pulse generating means is delivering pacing pulses at said sequence of pacing rates, for causing said pulse generating means to generate pulses at said first heart rate.
Claim 18
Dependent Claim
43 words
A cardiac pacer according to claim 11 wherein said means responsive to detected heart depolarizations while said pulse generating means is delivering pacing pulses at said sequence of pacing rates comprises means responsive to a sequence of a defined number of heart depolarizations.
Claim 19
Dependent Claim
42 words
A cardiac pacer according to claim 10 wherein said means responsive to detected heart depolarizations while said pulse generating means is delivering pacing pulses at said second pacing rate comprises means responsive to a sequence of a defined number of heart depolarizations.
Claim 20
Independent Claim
87 words
A method of cardiac pacing; comprising: detecting depolarizations of a heart delivering cardiac pacing pulses at a first pacing rate; defining first and second threshold heart rates; detecting a rapid drop in spontaneous heart depolarization rate from a rate above said first threshold heart rate to a rate below said second threshold heart rate based on said detected heart depolarizations; and responsive to a said detected rapid drop in spontaneous heart depolarization rate delivering pacing pulses at a second pacing rate higher than said first pacing rate.
Claim 21
Independent Claim
87 words
A method of cardiac pacing; comprising: detecting depolarizations of a heart delivering cardiac pacing pulses at a first pacing rate; defining first and second threshold heart rates; detecting a rapid drop in spontaneous heart depolarization rate from a rate above said first threshold heart rate to a rate below said second threshold heart rate based on said detected heart depolarizations; and responsive to a said detected rapid drop in spontaneous heart depolarization rate delivering pacing pulses at a second pacing rate higher than said first pacing rate.
Claim 22
Dependent Claim
54 words
A method according to claim 14 wherein said drop detecting step comprises detecting a persistent heart depolarization rate above said first threshold heart rate and detecting a rapid drop in spontaneous heart depolarization rate from said persistent heart rate above said first threshold heart rate to a rate below said second threshold heart rate.
Claim 23
Dependent Claim
33 words
A method according to claim 15 wherein said step of detecting a persistent heart depolarization rate comprises detecting a sequence of a predetermined number of heart depolarizations above said first threshold heart rate.
Claim 24
Dependent Claim
53 words
A method according to claim 14 wherein said drop detecting step comprises detecting a stable heart depolarization rate below said second threshold heart rate and detecting a rapid drop in spontaneous heart depolarization rate from a rate above said first threshold heart rate to a stable rate below said second threshold heart rate.
Claim 25
Dependent Claim
38 words
A method according to claim 17 wherein said step of detecting a stable heart depolarization rate below said second threshold heart rate comprises detecting a predetermined proportion of heart depolarizations having rates less than said second threshold rate.
Claim 26
Independent Claim
72 words
A method of cardiac pacing, compromising: detecting heart depolarizations; delivering cardiac pacing pulses at a first pacing rate; defining a threshold heart rate; detecting a rapid drop in spontaneous heart depolarization rate from a rate above said threshold heart rate based on said detected heart depolarizations; and responsive to said detected rapid drop in spontaneous heart depolarization rate, delivering pacing pulses at a second pacing rate higher than said first pacing rate.
Claim 27
Independent Claim
72 words
A method of cardiac pacing, compromising: detecting heart depolarizations; delivering cardiac pacing pulses at a first pacing rate; defining a threshold heart rate; detecting a rapid drop in spontaneous heart depolarization rate from a rate above said threshold heart rate based on said detected heart depolarizations; and responsive to said detected rapid drop in spontaneous heart depolarization rate, delivering pacing pulses at a second pacing rate higher than said first pacing rate.
Claim 28
Dependent Claim
44 words
A method according to claim 19 wherein said drop detecting step comprises detecting a persistent heart depolarization rate above said threshold heart rate and detecting a rapid drop in spontaneous heart depolarization rate from said persistent heart depolarization rate above said threshold heart rate.
Claim 29
Dependent Claim
32 words
A method according to claim 20 wherein said step of detecting a persistent heart depolarization rate comprises detecting a sequence of a predetermined number of heart depolarizations above said threshold heart rate.
Claim 30
Independent Claim
103 words
A method of cardiac pacing, comprising: detecting heart depolarizations; delivering cardiac pacing pulses at a first pacing rate; defining a threshold heart rate; detecting a stable heart depolarization rate below said threshold heart rate in response to detecting a predetermined proportion of heart depolarizations having rates less than said threshold rate to heart depolarizations having a rate greater than said threshold rate; detecting a rapid drop in spontaneous heart depolarization rate to a stable rate below said threshold heart rate; and in response to detecting a said rapid drop, delivering pacing pulses at a second pacing rate higher than said first pacing rate.
Claim 31
Independent Claim
103 words
A method of cardiac pacing, comprising: detecting heart depolarizations; delivering cardiac pacing pulses at a first pacing rate; defining a threshold heart rate; detecting a stable heart depolarization rate below said threshold heart rate in response to detecting a predetermined proportion of heart depolarizations having rates less than said threshold rate to heart depolarizations having a rate greater than said threshold rate; detecting a rapid drop in spontaneous heart depolarization rate to a stable rate below said threshold heart rate; and in response to detecting a said rapid drop, delivering pacing pulses at a second pacing rate higher than said first pacing rate.
Claim 32
Independent Claim
77 words
A method of cardiac pacing, compromising: detecting heart depolarizations; delivering cardiac pacing pulses at a first pacing rate; detecting a rapid drop in spontaneous heart depolarization rate; responsive to said detected rapid drop in spontaneous heart depolarization rate, delivering pacing pulses at a second pacing rate instead of and higher than said first pacing rate; responsive to detected heart depolarizations while delivering pacing pulses at said second pacing rate, delivering pacing pulses at said first pacing rate.
Claim 33
Independent Claim
77 words
A method of cardiac pacing, compromising: detecting heart depolarizations; delivering cardiac pacing pulses at a first pacing rate; detecting a rapid drop in spontaneous heart depolarization rate; responsive to said detected rapid drop in spontaneous heart depolarization rate, delivering pacing pulses at a second pacing rate instead of and higher than said first pacing rate; responsive to detected heart depolarizations while delivering pacing pulses at said second pacing rate, delivering pacing pulses at said first pacing rate.
Claim 34
Dependent Claim
88 words
A method according to claim 23, wherein; said step of delivering pacing pulses at a second pacing rate comprises delivering pacing pulses at said second pacing rate for a defined time interval, and wherein said method further comprises: delivering pacing pulses at a sequence of pacing rates gradually decreasing from said second pacing rate to said first pacing rate, after said defined time interval; and responsive to detected heart depolarizations while delivering pacing pulses at said sequence of pacing rates, delivering pacing pulses at said first heart rate.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-03-26 | 1999-09-25 | 2000-03-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-03-26 | 2003-09-25 | 2004-03-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-03-26 | 2007-09-25 | 2008-03-26 | $7700.00 | Window Closed / Lapsed |