Patent US761215A successfully refreshed from Google Patents.
Patent US5500593A successfully refreshed from Google Patents.
US5500593A
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Phase rotated spoiling for spatial and spectral saturation techniques
Assignee: Philips Nuclear Medicine Inc
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Filing: 1994-11-23
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Granted: 1996-03-19
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Expires: 2014-11-23
Abstract
Abstract Magnets (12) create a temporally constant magnetic field through an examination region (14). Radio frequency coils (26, 34) and a transmitter (24) transmit radio frequency saturation pulses (52) and the resonance excitation and manipulation pulses of a magnetic resonance imaging sequence (72) into the examination region. Gradient amplifiers (20) and gradient coils (22, 32) create magnetic field gradients across the examination region for spatially focusing the saturation, for spoiling (62, 66, 70) residual transverse magnetization and for frequency and phase encoding in the magnetic resonance imaging sequence. A sequence controller (40) includes a saturation pulse controller (44) for generating the saturation pulse (52) and slice select gradients (58) and a steady state sequence controller (48) for generating the imaging sequence (72). The saturation is spectrally focused by limiting the frequency of the saturation pulse to selected frequencies. The saturation is spatially focused by applying the slice or other spatially limiting gradient pulses concurrently with the radio frequency saturation pulse. A phase shift controller (76) increments the phase of the RF saturation pulse by a preselected phase increment, e.g., 105°. Preferably, the phase shift increment increases linearly in each cyclic repetition, i.e., increases 105° in the first repetition, 210° in the next repetition, 315° in the next repetition, etc. A reconstruction processor (80) reconstructs resonance signals generated during the imaging sequences into an image representation for storage in a memory (82) and display on a video monitor (86).
Inventors
- 👤 Mark J. Loncar
- 👤 James B. Murdoch
- 👤 Rao P. Gullapalli
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 10:11
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/44; G01R33/48; G01R33/483; G01R33/4838
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
125 words
In a magnetic resonance method in which at least a portion of a subject is disposed in an examination region of a temporally constant magnetic field and in which the subject portion in the examination region is examined by cyclically (a) applying a presaturation RF pulse focused to saturate only selected material in the subject portion, (b) applying spoiler gradients, and (c) applying a magnetic resonance sequence for generating magnetic resonance signals from non-saturated material in the examination region, which magnetic resonance signals are received and processed, the improvement comprising causing spectrally selective presaturation in the selected material by: in each cyclic repetition, changing the phase of the presaturation radio frequency pulse independently of the phase of radio frequency pulses in the magnetic resonance sequence.
Claim 2
Dependent Claim
125 words
In a magnetic resonance method in which at least a portion of a subject is disposed in an examination region of a temporally constant magnetic field and in which the subject portion in the examination region is examined by cyclically (a) applying a presaturation RF pulse focused to saturate only selected material in the subject portion, (b) applying spoiler gradients, and (c) applying a magnetic resonance sequence for generating magnetic resonance signals from non-saturated material in the examination region, which magnetic resonance signals are received and processed, the improvement comprising causing spectrally selective presaturation in the selected material by: in each cyclic repetition, changing the phase of the presaturation radio frequency pulse independently of the phase of radio frequency pulses in the magnetic resonance sequence.
Claim 3
Dependent Claim
62 words
In the magnetic resonance imaging method of claim 1, the improvement further comprising: incrementing the phase shift of the presaturation radio frequency pulse by a linearly increasing increment of the phase step, whereby the phase shift increment between sequential cyclic repetitions is the phase step, twice the phase step, three times the phase step, four times the phase step, and so forth.
Claim 4
Independent Claim
135 words
A method of magnetic resonance imaging comprising: disposing a subject which includes material having a plurality of a relaxation times including a maximum relaxation time in an examination region; creating a temporally constant magnetic field through the examination region; cyclically: (i) in each cycle, applying a spatially focused radio frequency saturation pulse to cause saturation of a portion of the material in the examination region, (ii) in each cycle, applying a steady-state imaging sequence in which a phase of radio frequency pulses of the steady-state imaging sequence remain constant from cycle to cycle and collecting magnetic resonance data from the examination region; in each cycle, changing a phase shift of the saturation pulse such that the phase shift of the saturation changes from cycle to cycle; reconstructing an image representation from the magnetic resonance signals.
Claim 5
Independent Claim
135 words
A method of magnetic resonance imaging comprising: disposing a subject which includes material having a plurality of a relaxation times including a maximum relaxation time in an examination region; creating a temporally constant magnetic field through the examination region; cyclically: (i) in each cycle, applying a spatially focused radio frequency saturation pulse to cause saturation of a portion of the material in the examination region, (ii) in each cycle, applying a steady-state imaging sequence in which a phase of radio frequency pulses of the steady-state imaging sequence remain constant from cycle to cycle and collecting magnetic resonance data from the examination region; in each cycle, changing a phase shift of the saturation pulse such that the phase shift of the saturation changes from cycle to cycle; reconstructing an image representation from the magnetic resonance signals.
Claim 6
Dependent Claim
79 words
The method as set forth in claim 3 wherein the phase shift has a linearly increasing increment in which after the first cycle, the phase shift is incremented by a preselected phase step, in a second repetition, the phase shift is incremented by twice the preselected phase step, in a third repetition, the phase shift is incremented by three times the incremented phase step, in a fourth repetition, the phase shift is incremented by four times the phase step.
Claim 7
Dependent Claim
15 words
The method as set forth in claim 4 wherein the phase shift increment is 105°.
Claim 8
Dependent Claim
17 words
The method as set forth in claim 3 wherein the radio frequency saturation pulse is spectrally focused.
Claim 9
Dependent Claim
28 words
The method as set forth in claim 3 wherein the radio frequency saturation pulse is applied concurrently with a spatially limiting magnetic field gradient to provide spatial focusing.
Claim 10
Dependent Claim
170 words
In a magnetic resonance imaging apparatus which includes magnets for creating a temporally constant magnetic field through an examination region, a radio frequency coil and transmitter assembly for transmitting radio frequency saturation pulses, radio frequency resonance excitation pulses, and radio frequency resonance manipulation pulses into the examination region, a receiver for receiving magnetic resonance signals emanating from the examination region, gradient coils and gradient pulse amplifiers for applying magnetic field gradients along three orthogonal axes across the examination region, a sequence controller for controlling the gradient amplifiers and the transmitter to cause the transmitter and gradient amplifiers to implement imaging and other magnetic resonance procedures which include alternate saturation pulses and magnetic resonance sequences, and a reconstruction processor for processing received magnetic resonance signals, the improvement comprising: a means for incrementing a phase shift of the radio frequency saturation pulses without correspondingly incrementing relative phases of the radio frequency resonance excitation and manipulation pulses such that the phase shift of the radio frequency saturation pulses changes with each cyclic repetition.
Claim 11
Dependent Claim
170 words
In a magnetic resonance imaging apparatus which includes magnets for creating a temporally constant magnetic field through an examination region, a radio frequency coil and transmitter assembly for transmitting radio frequency saturation pulses, radio frequency resonance excitation pulses, and radio frequency resonance manipulation pulses into the examination region, a receiver for receiving magnetic resonance signals emanating from the examination region, gradient coils and gradient pulse amplifiers for applying magnetic field gradients along three orthogonal axes across the examination region, a sequence controller for controlling the gradient amplifiers and the transmitter to cause the transmitter and gradient amplifiers to implement imaging and other magnetic resonance procedures which include alternate saturation pulses and magnetic resonance sequences, and a reconstruction processor for processing received magnetic resonance signals, the improvement comprising: a means for incrementing a phase shift of the radio frequency saturation pulses without correspondingly incrementing relative phases of the radio frequency resonance excitation and manipulation pulses such that the phase shift of the radio frequency saturation pulses changes with each cyclic repetition.
Claim 12
Dependent Claim
215 words
A magnetic resonance imaging apparatus comprising: magnets for creating a temporally constant magnetic field through an examination region; a radio frequency coil disposed around the examination region; a transmitter connected with the radio frequency coil for transmitting radio frequency saturation, resonance excitation, and resonance manipulation signals into the examination region; a plurality of gradient coils disposed around the examination region for creating magnetic field gradients across the examination region; gradient pulse amplifiers connected with the gradient coils for applying current pulses to the gradient coils for selectively creating magnetic field gradient pulses across the examination region; a sequence controller connected with the transmitter and gradient amplifiers for cyclically (a) causing a preaturation sequence including transmitting a radio frequency presaturation pulse into the examination region for spectrally focusing saturation caused by the presaturation pulse and (b) causing the transmitter and gradient amplifiers to conduct a magnetic resonance imaging sequence which generates magnetic resonance signals; a phase shift controller for incrementing a phase shift of the radio frequency presaturation pulse by an increasing increment with each cyclic repetition of the presaturation sequence without correspondingly incrementing the phase of radio frequency pulses in the magnetic resonance imaging sequence; a processor for processing the magnetic resonance signals into electronic image and other representations; a memory for storing the representations.
Claim 13
Dependent Claim
215 words
A magnetic resonance imaging apparatus comprising: magnets for creating a temporally constant magnetic field through an examination region; a radio frequency coil disposed around the examination region; a transmitter connected with the radio frequency coil for transmitting radio frequency saturation, resonance excitation, and resonance manipulation signals into the examination region; a plurality of gradient coils disposed around the examination region for creating magnetic field gradients across the examination region; gradient pulse amplifiers connected with the gradient coils for applying current pulses to the gradient coils for selectively creating magnetic field gradient pulses across the examination region; a sequence controller connected with the transmitter and gradient amplifiers for cyclically (a) causing a preaturation sequence including transmitting a radio frequency presaturation pulse into the examination region for spectrally focusing saturation caused by the presaturation pulse and (b) causing the transmitter and gradient amplifiers to conduct a magnetic resonance imaging sequence which generates magnetic resonance signals; a phase shift controller for incrementing a phase shift of the radio frequency presaturation pulse by an increasing increment with each cyclic repetition of the presaturation sequence without correspondingly incrementing the phase of radio frequency pulses in the magnetic resonance imaging sequence; a processor for processing the magnetic resonance signals into electronic image and other representations; a memory for storing the representations.
Claim 14
Dependent Claim
43 words
The magnetic resonance apparatus as set forth in claim 9 further including a video processor for selectively retrieving portions of the image representations stored in the memory and converting the retrieved image representation portions into video format for display on a video monitor.
Claim 15
Dependent Claim
197 words
A magnetic resonance imaging apparatus comprising: magnets for creating a temporally constant magnetic field through an examination region; a radio frequency coil disposed adjacent the examination region; a transmitter connected with the radio frequency coil for transmitting RF saturation, resonance excitation, and resonance manipulation signals into the examination region; a plurality of gradient coils disposed around the examination region for creating magnetic field gradients across the examination region; gradient pulse amplifiers connected with the gradient coils for applying current pulses to the gradient coils for selectively creating magnetic field gradient pulses across the examination region; a sequence controller connected with the transmitter and gradient amplifiers for cyclically (a) causing a presaturation cycle portion including an RF saturation pulse for causing spatially focused saturation and (b) causing a magnetic resonance imaging sequence portion including RF resonance excitation and manipulation pulses which induces magnetic resonance signals; a phase incrementor which increments the phase of the RF saturation pulse by an increasing increment with each cyclic repetition without incrementing the phase of the RF resonance excitation and manipulation signals correspondingly; a processor for processing the magnetic resonance signals into electronic image and other representations; a memory for storing the representations.
Claim 16
Dependent Claim
197 words
A magnetic resonance imaging apparatus comprising: magnets for creating a temporally constant magnetic field through an examination region; a radio frequency coil disposed adjacent the examination region; a transmitter connected with the radio frequency coil for transmitting RF saturation, resonance excitation, and resonance manipulation signals into the examination region; a plurality of gradient coils disposed around the examination region for creating magnetic field gradients across the examination region; gradient pulse amplifiers connected with the gradient coils for applying current pulses to the gradient coils for selectively creating magnetic field gradient pulses across the examination region; a sequence controller connected with the transmitter and gradient amplifiers for cyclically (a) causing a presaturation cycle portion including an RF saturation pulse for causing spatially focused saturation and (b) causing a magnetic resonance imaging sequence portion including RF resonance excitation and manipulation pulses which induces magnetic resonance signals; a phase incrementor which increments the phase of the RF saturation pulse by an increasing increment with each cyclic repetition without incrementing the phase of the RF resonance excitation and manipulation signals correspondingly; a processor for processing the magnetic resonance signals into electronic image and other representations; a memory for storing the representations.
Claim 17
Dependent Claim
39 words
The magnetic resonance apparatus as set forth in claim 9 wherein the transmitter transmits frequency specific radio frequency pulses and further including a means for selecting the frequency of the radio frequency pulses for spatially focusing the saturation pulses.
Claim 18
Dependent Claim
38 words
The magnetic resonance apparatus as set forth in claim 12 wherein the sequence controller includes a means for causing the gradient amplifiers to cause a spatial select gradient concurrently with the saturation pulse for spatially focusing the saturation.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-03-19 | 1999-09-18 | 2000-03-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-03-19 | 2003-09-18 | 2004-03-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-03-19 | 2007-09-18 | 2008-03-19 | $7700.00 | Window Closed / Lapsed |