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US5500005A Expired / Lapsed US ⏱️ 0.0 years remaining

Activity responsive heart stimulator dependent on return blood flow to the heart

Assignee: Pacesetter AB
•
Filing: 1994-07-07
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Granted: 1996-03-19
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Expires: 2014-07-07
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Abstract

Abstract A heart stimulator emits stimulation pulses to a heart, and has a regulator unit for regulating a variable function in the heart stimulator, a measurement device for measuring the return flow of blood to the heart, and a control device for controlling the regulation of the function by the regulator unit on the basis of changes in the return flow of blood. The regulator unit may be a pulse generator which generates and emits the stimulation pulses at a variable interval, the heart stimulator then becoming rate-adaptive and optimizing cardiac output. In this manner, heart rate is regulated on the basis of a variable directly related to the body's oxygenation needs.

Inventors

  • 👤 Hans Strandberg
  • 👤 Kurt Hoegnelid

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 13:59
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/18; A61N1/32; A61N1/36; A61N1/362; A61N1/37; A61N1/3702

Claims Analysis

Total Claims: 21
Claim 1
Independent Claim 87 words
A heart stimulator, for stimulating a heart having a return flow of blood comprising: regulator means for regulating a variable function in said heart stimulator associated with stimulating said heart; measurement means for measuring said return flow of blood to the heart and for generating an electrical signal exclusively corresponding thereto; and control means for generating a control signal dependent on said electrical signal for supply to said regulator means for controlling regulation of said variable directly and exclusively function dependent on said return flow of blood.
Claim 2
Dependent Claim 87 words
A heart stimulator, for stimulating a heart having a return flow of blood comprising: regulator means for regulating a variable function in said heart stimulator associated with stimulating said heart; measurement means for measuring said return flow of blood to the heart and for generating an electrical signal exclusively corresponding thereto; and control means for generating a control signal dependent on said electrical signal for supply to said regulator means for controlling regulation of said variable directly and exclusively function dependent on said return flow of blood.
Claim 3
Dependent Claim 80 words
A heart stimulator as claimed in claim 1 wherein said means for measuring said return flow of blood includes first and second electrodes adapted to be disposed in said return flow of blood, and voltage supply means, connected across said first and second electrodes, for maintaining a constant voltage across said electrodes, said constant voltage resulting in a variable current being drawn by said voltage supply means for maintaining said constant voltage and said variable current comprising said electrical signal.
Claim 4
Dependent Claim 35 words
A heart stimulator as claimed in claim 1 wherein said regulator means comprises a pulse generator for generating and emitting stimulation pulses to said heart at a variable stimulation interval controlled by said control signal.
Claim 5
Dependent Claim 43 words
A heart stimulator as claimed in claim 1 further comprising: averager means for determining an average value, from said electrical signal, of said return flow of blood, and wherein said control signal generated by said control means is dependent on said average value.
Claim 6
Dependent Claim 57 words
A heart stimulator as claimed in claim 4 wherein said averager comprises means for sampling a predetermined number of measured values represented by said electrical signal for the return flow of blood in each heart cycle, and means for determining said average value in a predetermined, preceding time interval from the predetermined number of sampled measured values.
Claim 7
Dependent Claim 59 words
A heart stimulator as claimed in claim 4 wherein said averager comprises means for sampling a predetermined number of measured values represented by said electrical signal for the return flow of blood in each heart cycle, and means for determining said average value in a predetermined number of preceding heart cycles from the predetermined number of sampled measured values.
Claim 8
Dependent Claim 54 words
A heart stimulator as claimed in claim 4 wherein said averager comprises means for determining a maximum value and a minimum value for said return flow of blood in each heart cycle, and means for determining said average value for a predetermined number of preceding heart cycles dependent on said maximum and minimum values.
Claim 9
Dependent Claim 40 words
A heart stimulator as claimed in claim 4 wherein said averager comprises means for determining said average value for a continuous measurement signal corresponding to said electrical signal for the return flow of blood for a predetermined preceding time interval.
Claim 10
Dependent Claim 43 words
A heart stimulator as claimed in claim 4 wherein said averager comprises means for determining said average value for a continuous measurement signal corresponding to said electrical signal for the return flow of blood for a predetermined preceding number of preceding heart cycles.
Claim 11
Dependent Claim 96 words
A heart stimulator as claimed in claim 1 further comprising: a first tip electrode adapted for placement in an atrium of said heart; a second tip electrode adapted for placement in a ventricle of said heart; said regulator means comprises pulse generator means, connected to each of said first and second tip electrodes, for respectively emitting stimulation pulses to the atrium and to the ventricle; and said regulator means including timer means for setting a time interval between emission of an atrial stimulation pulse and emission of a ventricular stimulation pulse dependent on said control signal.
Claim 12
Dependent Claim 66 words
A heart stimulator as claimed in claim 1 further comprising: means for monitoring changes in said electrical signal corresponding to the return flow of blood generated by said means for measuring and for identifying a momentary change in said electrical signal exceeding a predetermined threshold value as being abnormal and for preventing the electrical signal corresponding to said momentary change from contributing to said control signal.
Claim 13
Dependent Claim 54 words
A heart stimulator as claimed in claim 1 further comprising: means for measuring at least one additional physiological variable, in addition to said return flow of blood, and wherein said control means comprises means for generating said control signal dependent on said return flow of blood and said at least one additional physiological variable.
Claim 14
Dependent Claim 27 words
A heart stimulator as claimed in claim 1 further comprising: memory means for storing values representing the return flow of blood for a predetermined period of time.
Claim 15
Dependent Claim 35 words
A heart stimulator as claimed in claim 13 wherein said memory means comprises means for storing a minimum value and a maximum value of said return flow of blood for said predetermined period of time.
Claim 16
Dependent Claim 131 words
A heart stimulator as claimed in claim 1 further comprising: a first tip electrode adapted for placement in an atrium of said heart; a second tip electrode adapted for placement in a ventricle of said heart; said regulator means comprises pulse generator means, connected to each of said first and second tip electrodes, for respectively emitting stimulation pulses to the atrium and to the ventricle; said regulator means including timer means for setting a time interval between emission of an atrial stimulation pulse and emission of a ventricular stimulation pulse dependent on said control signal; and memory means for storing values representing a plurality of said time intervals occurring during a predetermined period of time and for storing values representing the return flow of blood for said predetermined period of time.
Claim 17
Dependent Claim 57 words
A heart stimulator as claimed in claim 15 wherein said control means comprises means for calculating, dependent on said stored values representing the return flow of blood and the time intervals, a correlation between changes in said return flow of blood and changes in said time interval, and for setting said control signal dependent on said calculation.
Claim 18
Dependent Claim 43 words
A heart stimulator as claimed in claim 16 wherein said control means includes means for limiting changes in said time interval set by said control signal to changes within a predetermined interval defined by a minimum time interval and a maximum time interval.
Claim 19
Dependent Claim 139 words
A heart stimulator as claimed in claim 1 further comprising: a first tip electrode adapted for placement in an atrium of said heart; a second tip electrode adapted for placement in a ventricle of said heart; said regulator means comprises pulse generator means, connected to each of said first and second tip electrodes, for respectively emitting stimulation pulses to the atrium and to the ventricle; and said regulator means including timer means for setting a time interval between emission of an atrial stimulation pulse and emission of a ventricular stimulation pulse dependent on said control signal. memory means for storing values representing a maximum value and a minimum value among a plurality of said time intervals occurring during a predetermined period of time and for storing values representing the return flow of blood for said predetermined period of time.
Claim 20
Dependent Claim 65 words
A heart stimulator as claimed in claim 18 wherein said control means comprises means for calculating, dependent on said stored values representing the return flow of blood and the maximum value and the minimum value of said time intervals, a correlation between changes in said return flow of blood and changes in said time interval, and for setting said control signal dependent on said calculation.
Claim 21
Dependent Claim 41 words
A heart stimulator as claimed in claim 19 wherein said control means includes means for limiting changes in said time interval set by said control signal to changes within a predetermined interval defined by said minimum value and said maximum value.

References Cited (Backward Citations)

US4535774A Cited
EP0310026A2 Cited
EP0474958A2 Cited
EP0503839A2 Cited
WO1993002745A1 Cited
EP0591642A1 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1999-03-19 1999-09-18 2000-03-19 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2003-03-19 2003-09-18 2004-03-19 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2007-03-19 2007-09-18 2008-03-19 $7700.00 Window Closed / Lapsed

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