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Method for lowering plasma levels of lipoprotein (a)

Assignee: Warner Lambert Co LLC
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Filing: 1995-02-10
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Granted: 1996-02-06
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Expires: 2015-02-10
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Abstract

Abstract Retinoids are effective to lower plasma levels of Lp (a) in mammals.

Inventors

  • 👤 Helen T. Lee
  • 👤 Joseph A. Picard
  • 👤 Randy R. Ramharack
  • 👤 Bruce D. Roth
  • 👤 Drago R. Sliskovic

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 16:44
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/11; A61K31/045; A61K31/07; A61K31/185; A61K31/19; A61K31/20; A61K31/203; A61K31/21; A61K31/215; A61P; A61P7/00

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 19 words
A method of lowering plasma Lp(a) levels in a mammal comprising administering an Lp(a) lowering amount of a retinoid.
Claim 2
Independent Claim 19 words
A method of lowering plasma Lp(a) levels in a mammal comprising administering an Lp(a) lowering amount of a retinoid.
Claim 3
Dependent Claim 9 words
A method of claim 1 employing all trans-retinoic acid.
Claim 4
Dependent Claim 10 words
A method of claim 1 employing 3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid, methyl ester.
Claim 5
Dependent Claim 8 words
A method of claim 1 employing all trans-retinal.
Claim 6
Dependent Claim 8 words
A method of claim 1 employing all trans-retinol.
Claim 7
Dependent Claim 8 words
A method of claim 1 employing 9-cis-retinoic acid.
Claim 8
Dependent Claim 7 words
A method of claim 1 employing 13-cis-retinol.
Claim 9
Dependent Claim 7 words
A method of claim 1 employing 13-cis-retinal.
Claim 10
Dependent Claim 7 words
A method of claim 1 employing 9-cis-retinol.
Claim 11
Dependent Claim 8 words
A method of claim 1 employing 13-cis-retinoic acid.
Claim 12
Dependent Claim 7 words
A method of claim 1 employing 9-cis-retinal.

References Cited (Backward Citations)

US5219888A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1999-02-05 1999-08-07 2000-02-06 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2003-02-05 2003-08-07 2004-02-06 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2007-02-05 2007-08-07 2008-02-06 $7700.00 Window Closed / Lapsed

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