US5486547A
Expired / Lapsed
US
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Surgical adhesive sheet, surgical instruments and methods of using the same
Assignee: Sanyo Chemical Industries Ltd
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Filing: 1994-11-03
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Granted: 1996-01-23
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Expires: 2014-11-03
Abstract
Abstract A sheet material, coated with a surgical adhesive comprising an NCO-terminated urethane prepolymer, is used for bonding of tissues, with improved handleability. Surgical instruments, comprising a non-adherent material towards an NCO-terminated urethane prepolymer, are used for application of surgical adhesive. Such instruments, comprising a rod tapered so that the tip can be partly inserted into blood vessel, are suitable for anastomosis of blood vessel.
Inventors
- 👤 Takehisa Matsuda
- 👤 Tetsuo Itoh
- 👤 Tohru Tani
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:05
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61B; A61B17/00; A61B17/00491; A61B17/11; A61F13/00; A61F13/01; A61F13/01008; A61F13/01012; A61F13/02; A61F13/0203; A61F13/0206; A61F13/0209; A61F13/0226; A61L; A61L31/00; A61L31/08; A61L31/10; A61B17/1114; A61B2017/1107; A61B2017/1125; A61F13/023; A61F13/0273; A61F13/15; A61F13/15203; A61F13/15252; A61F13/551; A61F2/0063; A61F2013/00361; A61F2013/00365; A61F2013/00463; A61F2013/00472; A61F2013/00489; A61F2013/00519; A61F2013/00544; A61F2013/00604; A61F2013/00655; A61F2013/00659; A61F2013/00719; A61F2013/00902; A61F2013/0091; A61F2013/00927; Y; Y10; Y10S; Y10S528/00; Y10S528/905; Y10T; Y10T428/00; Y10T428/31504; Y10T428/31551; Y10T428/31554; Y10T428/31562; Y10T428/31573; Y10T428/31576; Y10T428/3158; Y10T428/31587; Y10T428/31591; Y10T428/31598
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
62 words
A surgical adhesive sheet, comprising a sheet material comprising at least one polymer selected from the group consisting of polyurethane resins, silicone resins and fluorine-containing resins, coated with a surgical adhesive comprising an NCO-terminated urethane prepolymer having a free isocyanate group content of 2-10% by weight, wherein said sheet is anhydrous or contains water in an amount insufficient to crosslink the prepolymer.
Claim 2
Dependent Claim
62 words
A surgical adhesive sheet, comprising a sheet material comprising at least one polymer selected from the group consisting of polyurethane resins, silicone resins and fluorine-containing resins, coated with a surgical adhesive comprising an NCO-terminated urethane prepolymer having a free isocyanate group content of 2-10% by weight, wherein said sheet is anhydrous or contains water in an amount insufficient to crosslink the prepolymer.
Claim 3
Dependent Claim
21 words
The surgical adhesive sheet of claim 1, said sheet material being a film capable of transferring said surgical adhesive to tissue.
Claim 4
Dependent Claim
79 words
A surgical adhesive sheet, comprising a biodegradable sheet material comprising at least one polymer selected from the group consisting of polyamino acids, polyamino acid copolymers, oxidized cellulose, chitin, collagen, polylactic acids, polyglycolic acids, polyhydroxybutyric acids, and copolymers of lactic acid and glycolic acid, coated with a surgical adhesive comprising an NCO-terminated urethane prepolymer having a free isocyanate group content of 2-10% by weight, wherein said sheet is anhydrous or contains water in an amount insufficient to crosslink the prepolymer.
Claim 5
Dependent Claim
79 words
A surgical adhesive sheet, comprising a biodegradable sheet material comprising at least one polymer selected from the group consisting of polyamino acids, polyamino acid copolymers, oxidized cellulose, chitin, collagen, polylactic acids, polyglycolic acids, polyhydroxybutyric acids, and copolymers of lactic acid and glycolic acid, coated with a surgical adhesive comprising an NCO-terminated urethane prepolymer having a free isocyanate group content of 2-10% by weight, wherein said sheet is anhydrous or contains water in an amount insufficient to crosslink the prepolymer.
Claim 6
Dependent Claim
40 words
The sheet of claim 1, wherein said prepolymer is derived from at least one organic polyisocyanate and a polyol component comprising at least one hydrophilic polyether polyol having an oxyethylene content of at least 30% by weight of the polyol.
Claim 7
Dependent Claim
22 words
The sheet of claim 4, wherein said polyol component has an equivalent weight (average) of 100-5,000 and a functionality (average) of 2-8.
Claim 8
Dependent Claim
70 words
The sheet of claim 4, wherein said polyisocyanate is at least one selected from the group consisting of aromatic polyisocyanates containing 6-20 carbon atoms, aliphatic polyisocyanates containing 2-18 carbon atoms, allcyclic polyisocyanates containing 4-15 carbon atoms, araliphatic polyisocyanates containing 8-15 carbon atoms, except carbon atoms in NCO groups, and modified polyisocyanates of these polyisocyanates containing one or more of urethane, carbodiimide, allophanate, urea, biuret, urethdione, urethimine, isocyanurate and oxazolidone groups.
Claim 9
Dependent Claim
12 words
The sheet of claim 4, wherein said polyisocyanate comprises a fluorine-containing polyisocyanate.
Claim 10
Dependent Claim
40 words
The sheet of claim 3, wherein said prepolymer is derived from at least one organic polyisocyanate and a polyol component comprising at least one hydrophilic polyether polyol having an oxyethylene content of at least 30% by weight of the polyol.
Claim 11
Dependent Claim
22 words
The sheet of claim 8, wherein said polyol component has an equivalent weight (average) of 100-5,000 and a functionality (average) of 2-8.
Claim 12
Dependent Claim
70 words
The sheet of claim 8, wherein said polyisocyanate is at least one selected from the group consisting of aromatic polyisocyanates containing 6-20 carbon atoms, aliphatic polyisocyanates containing 2-18 carbon atoms, alicyclic polyisocyanates containing 4-15 carbon atoms, araliphatic polyisocyanates containing 8-15 carbon atoms, except carbon atoms in NCO groups, and modified polyisocyanates of these polyisocyanates containing one or more of urethane, carbodiimide, allophanate, urea, biuret, urethdione, urethimine, isocyanurate and oxazolidone groups.
Claim 13
Dependent Claim
12 words
The sheet of claim 8, wherein said polyisocyanate comprises a fluorine-containing polyisocyanate.
Claim 14
Dependent Claim
18 words
The sheet of claim 5, wherein the maximum average molecular weight of the polyol component is about 4,000.
Claim 15
Dependent Claim
18 words
The sheet of claim 9, wherein the maximum average molecular weight of the polyol component is about 4,000.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-01-22 | 1999-07-24 | 2000-01-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-01-22 | 2003-07-24 | 2004-01-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-01-22 | 2007-07-24 | 2008-01-23 | $7700.00 | Window Closed / Lapsed |