US5474080A
Expired / Lapsed
US
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Method for monitoring cardiac output and protecting blood and tissue
Assignee: Abbott Laboratories
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Filing: 1993-10-08
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Granted: 1995-12-12
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Expires: 2013-10-08
Abstract
Abstract A method of using a heated catheter for monitoring cardiac output. Displaced from a distal end of a heated catheter (30) is a resistive heater (39) that heats blood flowing within a heart muscle (10). The resistive heater is mounted on the catheter so that when the catheter is inserted into the heart, the resistive heater is disposed in the right ventricle. A temperature sensor (34) is disposed downstream of the resistive heater, in or proximate the pulmonary artery during use. The temperature of the resistive heater is monitored using the temperature sensor to prevent the temperature from exceeding a predetermined level. A differential amplifier (40, 70) provides an electrical current to the resistive heater that varies as a function of the difference between the temperature of the resistive heater, measured by a temperature sensor (35), and a predetermined temperature. In another embodiment of the invention, a resistive heater (90) has a resistance that varies with temperature. The resistive heater comprises one arm of a bridge circuit (85). A differential amplifier (110) provides an electrical current to the bridge circuit in response to the voltage developed across the bridge circuit. In yet another embodiment, a constant power dissipation is maintained in a resistive heater (60), so long as its temperature does not exceed a predetermined maximum. Should that occur, a power control block (80) incrementally reduces the power dissipated in the resistive heater, thereby insuring that the temperature of the resistive heater does not damage blood cells, yet is sufficient to provide a good signal-to-noise ratio in respect to a signal indicative of the temperature rise in blood flowing from the heart.
Inventors
- 👤 Timothy J. Hughes
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:11
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/02; A61B5/026; A61B5/0275; A61B5/028; A61B5/029
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
97 words
A method for protecting blood and tissue from damage due to overheating caused by heat transfer from a catheter used to monitor cardiac output, comprising the steps of: introducing the catheter for monitoring cardiac output intravascularly into a patient's heart; monitoring a temperature of a heated portion of the catheter and producing a signal indicative thereof; and controlling the temperature of the heated portion in response to the signal, to prevent the temperature from exceeding a predetermined maximum safe level to protect blood and tissue from damage due to overheating caused by heat transfer from the catheter.
Claim 2
Independent Claim
97 words
A method for protecting blood and tissue from damage due to overheating caused by heat transfer from a catheter used to monitor cardiac output, comprising the steps of: introducing the catheter for monitoring cardiac output intravascularly into a patient's heart; monitoring a temperature of a heated portion of the catheter and producing a signal indicative thereof; and controlling the temperature of the heated portion in response to the signal, to prevent the temperature from exceeding a predetermined maximum safe level to protect blood and tissue from damage due to overheating caused by heat transfer from the catheter.
Claim 3
Dependent Claim
70 words
The method of claim 1, wherein the step of monitoring the temperature comprises the steps of measuring an electrical current flowing through a resistive heater used to provide heat, measuring a voltage drop across the resistive heater, and determining the temperature of the heated portion of the catheter, the temperature of the heated portion of the catheter being proportional to a ratio of the voltage drop and the electrical current.
Claim 4
Dependent Claim
59 words
The method of claim 1, wherein an electrical current flowing through a resistive heater is used to provide heat and wherein the step of monitoring the temperature comprises the steps of monitoring a potential difference developed across a bridge circuit comprising the resistive heater and determining the temperature of the heated portion of the catheter using the potential difference.
Claim 5
Independent Claim
136 words
A method for protecting blood and tissue from damage due to overheating caused by heat transfer from a catheter used to monitor cardiac output, comprising the steps of: (a) introducing the catheter for monitoring cardiac output intravascularly into a patient's heart; (b) establishing a nominal fixed power distribution for heating the blood; (c) monitoring a temperature of a portion of the catheter where heat is transferred to the blood, producing a signal indicative thereof; and (d) in response to the signal, establishing a decreased nominal fixed power dissipation for heating the blood so that the temperature of the portion of the catheter where heat is transferred to the blood is reduced to at least a predetermined maximum safe value to protect blood and tissue from damage due to overheating caused by heat transfer from the catheter.
Claim 6
Independent Claim
136 words
A method for protecting blood and tissue from damage due to overheating caused by heat transfer from a catheter used to monitor cardiac output, comprising the steps of: (a) introducing the catheter for monitoring cardiac output intravascularly into a patient's heart; (b) establishing a nominal fixed power distribution for heating the blood; (c) monitoring a temperature of a portion of the catheter where heat is transferred to the blood, producing a signal indicative thereof; and (d) in response to the signal, establishing a decreased nominal fixed power dissipation for heating the blood so that the temperature of the portion of the catheter where heat is transferred to the blood is reduced to at least a predetermined maximum safe value to protect blood and tissue from damage due to overheating caused by heat transfer from the catheter.
Claim 7
Independent Claim
113 words
A method for protecting blood and tissue from damage due to overheating caused by heat transfer from a catheter used to monitor cardiac output, comprising the steps of: introducing the catheter for monitoring cardiac output intravascularly into a patient's heart; sensing a temperature of a resistive heater, mounted on a distal end of the catheter, after insertion into a patient's body; producing a signal indicative of the temperature of the resistive heater; and controlling an electrical current flowing through the resistive heater so that the temperature of the resistive heater does not exceed a predetermined value to protect blood and tissue from damage due to overheating caused by heat transfer from the catheter.
Claim 8
Independent Claim
113 words
A method for protecting blood and tissue from damage due to overheating caused by heat transfer from a catheter used to monitor cardiac output, comprising the steps of: introducing the catheter for monitoring cardiac output intravascularly into a patient's heart; sensing a temperature of a resistive heater, mounted on a distal end of the catheter, after insertion into a patient's body; producing a signal indicative of the temperature of the resistive heater; and controlling an electrical current flowing through the resistive heater so that the temperature of the resistive heater does not exceed a predetermined value to protect blood and tissue from damage due to overheating caused by heat transfer from the catheter.
Claim 9
Dependent Claim
56 words
The method of claim 5, wherein the step of sensing the temperature comprises the steps of measuring the electric current flowing through the resistive heater and measuring a voltage drop across the resistive heater, the temperature of the heated portion of the catheter being proportional to a ratio of the electric current and the voltage drop.
Claim 10
Independent Claim
105 words
A method for determining cardiac output based upon a temperature rise of blood in a patient's heart, comprising the steps of: placing a catheter including a resistive heater located adjacent a distal end thereof intravascularly into a patient's heart; monitoring a temperature of the resistive heater and producing a signal indicative of the temperature; controlling the temperature of the resistive heater in response to the signal, to prevent the temperature from exceeding a predetermined maximum safe level; measuring electrical power dissipated in the resistive heater and producing a signal indicative of the power dissipated; and determining cardiac output as a function of the power dissipated.
Claim 11
Independent Claim
105 words
A method for determining cardiac output based upon a temperature rise of blood in a patient's heart, comprising the steps of: placing a catheter including a resistive heater located adjacent a distal end thereof intravascularly into a patient's heart; monitoring a temperature of the resistive heater and producing a signal indicative of the temperature; controlling the temperature of the resistive heater in response to the signal, to prevent the temperature from exceeding a predetermined maximum safe level; measuring electrical power dissipated in the resistive heater and producing a signal indicative of the power dissipated; and determining cardiac output as a function of the power dissipated.
Claim 12
Dependent Claim
70 words
The method of claim 7, wherein the step of monitoring the temperature comprises the steps of measuring an electrical current flowing through the resistive heater, measuring a voltage drop across the resistive heater, and determining the temperature of the resistive heater, wherein the temperature of the resistive heater is proportional to a ratio of the voltage drop across the resistive heater and the electrical current flowing through the resistive heater.
Claim 13
Independent Claim
118 words
A method for protecting blood and tissue from damage due to overheating caused by heat transfer from a catheter used to monitor cardiac output, comprising the steps of: introducing the catheter for monitoring cardiac output intravascularly into a patient's heart; supplying an electrical current to a resistive heater located at a distal end of the catheter; monitoring a temperature of the resistive heater and producing a signal indicative of the temperature; and controlling the electrical current flowing through the resistive heater in response to the signal to prevent the temperature of the resistive heater from exceeding a predetermined maximum safe level to protect blood and tissue from damage due to overheating caused by heat transfer from the catheter.
Claim 14
Independent Claim
118 words
A method for protecting blood and tissue from damage due to overheating caused by heat transfer from a catheter used to monitor cardiac output, comprising the steps of: introducing the catheter for monitoring cardiac output intravascularly into a patient's heart; supplying an electrical current to a resistive heater located at a distal end of the catheter; monitoring a temperature of the resistive heater and producing a signal indicative of the temperature; and controlling the electrical current flowing through the resistive heater in response to the signal to prevent the temperature of the resistive heater from exceeding a predetermined maximum safe level to protect blood and tissue from damage due to overheating caused by heat transfer from the catheter.
Claim 15
Dependent Claim
19 words
The method of claim 9, wherein the controlling step further comprises controlling a voltage drop across the resistive heater.
Claim 16
Independent Claim
135 words
A method for monitoring cardiac output based upon a temperature rise of blood flowing through a heart and for protecting the blood and tissue from damage due to overheating, comprising the steps of: placing a catheter having a resistive heater located at a distal end intravascularly into a heart; providing an electrical current to the resistive heater in order to elevate a temperature of the blood; monitoring a temperature of the blood heated by the resistive heater; sensing a temperature of the resistive heater and producing a signal indicative thereof; controlling the temperature of the resistive heater in response to the signal so that the temperature of the resistive heater does not exceed a predetermined value; measuring electrical power dissipated in the resistive heater; and determining cardiac output as a function of the power dissipated.
Claim 17
Independent Claim
135 words
A method for monitoring cardiac output based upon a temperature rise of blood flowing through a heart and for protecting the blood and tissue from damage due to overheating, comprising the steps of: placing a catheter having a resistive heater located at a distal end intravascularly into a heart; providing an electrical current to the resistive heater in order to elevate a temperature of the blood; monitoring a temperature of the blood heated by the resistive heater; sensing a temperature of the resistive heater and producing a signal indicative thereof; controlling the temperature of the resistive heater in response to the signal so that the temperature of the resistive heater does not exceed a predetermined value; measuring electrical power dissipated in the resistive heater; and determining cardiac output as a function of the power dissipated.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-12-11 | 1999-06-12 | 1999-12-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-12-11 | 2003-06-12 | 2003-12-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-12-11 | 2007-06-12 | 2007-12-12 | $7700.00 | Window Closed / Lapsed |