US5464388A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Cardioplegia administration system and method
Assignee: Terumo Cardiovascular Systems Corp
•
Filing: 1995-02-06
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Granted: 1995-11-07
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Expires: 2015-02-06
Abstract
Abstract A cardioplegia administration system includes a tubing set, a positive displacement pump and a mixing system. The tubing set has a cardioplegia supply tube; a blood supply tube; and a cardioplegia administration tube connected to the cardioplegia and blood supply tubes. The positive displacement pump engages the cardioplegia administration tube to pump fluid therethrough. The mixing system includes pinch valves for alternately-continually pinching the cardioplegia and blood supply tubes to close and open the cardioplegia and blood supply tubes such that only one of the cardioplegia and blood supply tubes is open at a time, and a controller that controls the intervals during which the pinch valves are open to control the ratio of the cardioplegia medication and blood or blood substitute administered through the cardioplegia administration tube. The method of this invention includes the step, among others, of operating the pinch valves to close and open the cardioplegia and blood supply tubes so that only one of the cardioplegia and blood supply tubes is open at a time while controlling the intervals during which the pinch valves are open to control the ratio of the cardioplegia medication and blood or blood substitute administered through the cardioplegia administration tube.
Inventors
- 👤 Kenneth E. Merte
- 👤 William G. O'Neill
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 13:28
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/168; A61M5/16804; A61M5/16827; A61M1/00; A61M1/36; A61M1/3621; A61M1/3622; A61M1/36222; A61M1/362227; A61M1/36226; A61M1/362265; A61M1/3664; A61M2205/00; A61M2205/12; A61M2205/36; A61M2205/366; Y; Y10; Y10S; Y10S128/00; Y10S128/13
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
230 words
A replaceable tubing set cassette adapted for use with a mixer device for selectively mixing two or more medical fluids, the tubing set cassette comprising: a first supply tube, a second supply tube, and a mixing tube, the first supply tube having upstream and downstream ends, the upstream end of the first supply tube being adapted to connect the first supply tube to a source of a first biological or medical fluid; the second supply tube having upstream and downstream ends, the upstream end of the second supply tube being adapted to connect the second supply tube to a source of a second biological or medical fluid; and the mixing tube having an upstream end connected to the downstream ends of the first and second supply tubes, and a downstream end for supplying a mixed fluid comprising a preselected composition of the first and second fluids, the mixing tube having a lumen, in which the first and second fluids are mixed, and an exterior surface separated from the lumen by a tube wall; at least portions of the first and second supply tubes being contained in a cassette that is adapted to be mounted on the mixer device, the cassette having at least one opening therein allowing access to the first and second supply tubes so that the mixer device can selectively pinch the first and second supply tubes closed.
Claim 2
Dependent Claim
230 words
A replaceable tubing set cassette adapted for use with a mixer device for selectively mixing two or more medical fluids, the tubing set cassette comprising: a first supply tube, a second supply tube, and a mixing tube, the first supply tube having upstream and downstream ends, the upstream end of the first supply tube being adapted to connect the first supply tube to a source of a first biological or medical fluid; the second supply tube having upstream and downstream ends, the upstream end of the second supply tube being adapted to connect the second supply tube to a source of a second biological or medical fluid; and the mixing tube having an upstream end connected to the downstream ends of the first and second supply tubes, and a downstream end for supplying a mixed fluid comprising a preselected composition of the first and second fluids, the mixing tube having a lumen, in which the first and second fluids are mixed, and an exterior surface separated from the lumen by a tube wall; at least portions of the first and second supply tubes being contained in a cassette that is adapted to be mounted on the mixer device, the cassette having at least one opening therein allowing access to the first and second supply tubes so that the mixer device can selectively pinch the first and second supply tubes closed.
Claim 3
Dependent Claim
61 words
The replaceable tubing set cassette according to claim 1 further comprising a recirculation tube having upstream and downstream ends in fluid communication with the mixing tube, a portion of the recirculation tube being in the cassette, and wherein the cassette has an opening therein allowing access to the recirculation tube so that the mixer can selectively pinch the recirculation tube closed.
Claim 4
Dependent Claim
16 words
The replaceable tubing set cassette according to claim 2 wherein the cassette comprises a box-like frame.
Claim 5
Dependent Claim
35 words
The replaceable tubing set cassette according to claim 3 further comprising a pressure line connected to a contact mounted in the cassette, the contact being adapted for operative engagement with a contact in the device.
Claim 6
Dependent Claim
31 words
The replaceable tubing set cassette according to claim 4 further comprising a three-way Y-type connector within the cassette connecting the first supply tube, second supply tube, mixing tube and recirculation tube.
Claim 7
Dependent Claim
79 words
The replaceable tubing set cassette according to claim 5 wherein the first supply tube, second supply tube and recirculation tube each include exposed portions within the cassette exposed through the opening to allow access to the exposed portions to allow the mixer device to pinch the exposed portions, the cassette further comprises mounting blocks in the cassette for holding the exposed portions of the first supply tube, second supply tube and recirculation tube across the opening of the cassette.
Claim 8
Dependent Claim
33 words
The replaceable tubing set cassette according to claim 6 wherein the mounting blocks hold the exposed portions of the first supply tube, second supply tube and recirculation tube generally parallel to one another.
Claim 9
Dependent Claim
31 words
The replaceable tubing set cassette according to claim 2 further comprising a three-way Y-type connector within the cassette connecting the first supply tube, second supply tube, mixing tube and recirculation tube.
Claim 10
Dependent Claim
79 words
The replaceable tubing set cassette according to claim 2 wherein the first supply tube, second supply tube and recirculation tube each include exposed portions within the cassette exposed through the opening to allow access to the exposed portions to allow the mixer device to pinch the exposed portions, the cassette further comprises mounting blocks in the cassette for holding the exposed portions of the first supply tube, second supply tube and recirculation tube across the opening of the cassette.
Claim 11
Dependent Claim
33 words
The replaceable tubing set cassette according to claim 9 wherein the mounting blocks hold the exposed portions of the first supply tube, second supply tube and recirculation tube generally parallel to one another.
Claim 12
Dependent Claim
31 words
The replaceable tubing set cassette according to claim 10 further comprising a three-way Y-type connector within the cassette connecting the first supply tube, second supply tube, mixing tube and recirculation tube.
Claim 13
Dependent Claim
16 words
The replaceable tubing set cassette according to claim 1 wherein the cassette comprises a box-like frame.
Claim 14
Dependent Claim
35 words
The replaceable tubing set cassette according to claim 1 further comprising a pressure line connected to a contact mounted in the cassette, the contact being adapted for operative engagement with a contact in the device.
Claim 15
Dependent Claim
28 words
The replaceable tubing set cassette according to claim 1 further comprising a Y-type connector within the cassette connecting the first supply tube, second supply tube and mixing tube.
Claim 16
Dependent Claim
75 words
The replaceable tubing set cassette according to claim 1 wherein the first supply tube and second supply tube each include exposed portions within the cassette exposed through the opening to allow access to the exposed portions to allow the mixer device to pinch the exposed portions, the cassette further comprises mounting blocks in the cassette for holding the exposed portions of the first supply tube and second supply tube across the opening of the cassette.
Claim 17
Dependent Claim
31 words
The replaceable tubing set cassette according to claim 15 wherein the mounting blocks hold the exposed portions of the first supply tube and second supply tube generally parallel to one another.
Claim 18
Dependent Claim
28 words
The replaceable tubing set cassette according to claim 16 further comprising a Y-type connector within the cassette connecting the first supply tube, second supply tube and mixing tube.
Claim 19
Dependent Claim
35 words
The replaceable tubing set cassette according to claim 15 further comprising a pressure line connected to a contact mounted in the cassette, the contact being adapted for operative engagement with a contact in the device.
References Cited (Backward Citations)
US3927955A
Cited
US3776249A
Cited
US4038981A
Cited
US4011940A
Cited
US4105028A
Cited
US4187057A
Cited
US4256437A
Cited
US4259985A
Cited
US4249923A
Cited
US4526515A
Cited
US4637813A
Cited
US4425116A
Cited
US4333486A
Cited
US4372304A
Cited
US4445826A
Cited
US4496133A
Cited
US4425113A
Cited
US4512764A
Cited
US4537561A
Cited
US4493710A
Cited
US4559036A
Cited
US5304126A
Cited
US4651898A
Cited
US4524802A
Cited
US4673389A
Cited
US4714463A
Cited
US4887636A
Cited
US4626241A
Cited
US4681563A
Cited
US4713051A
Cited
US4888004A
Cited
US4735558A
Cited
US4830581A
Cited
US4889148A
Cited
US4798580A
Cited
US5195960A
Cited
US5125891A
Cited
US4842584A
Cited
US4793589A
Cited
US4925444A
Cited
US5207642A
Cited
US4874359A
Cited
US4998914A
Cited
US5320502A
Cited
US4846177A
Cited
EP0362822A2
Cited
US5044902A
Cited
US4993594A
Cited
WO1993019791A1
Cited
WO1991015149A1
Cited
US5094820A
Cited
US5057278A
Cited
US5199604A
Cited
US5154693A
Cited
US5350083A
Cited
US5181842A
Cited
US5094260A
Cited
EP0529902A2
Cited
US5267956A
Cited
US5318515A
Cited
US5403281A
Cited
US5306242A
Cited
US5403277A
Cited
US5328057A
Cited
US5385540A
Cited
US5358481A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-11-06 | 1999-05-08 | 1999-11-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-11-06 | 2003-05-08 | 2003-11-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-11-06 | 2007-05-08 | 2007-11-07 | $7700.00 | Window Closed / Lapsed |