Patent US5458653A successfully refreshed from Google Patents.
US5458653A
Expired / Lapsed
US
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Prosthetic implants with bioabsorbable coatings
Assignee: Smith and Nephew Inc
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Filing: 1993-05-11
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Granted: 1995-10-17
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Expires: 2013-05-11
Abstract
Abstract A novel coated prosthesis that can be tailored to avoid the problem of bone resorption caused by stress shielding. The permanent, load-bearing skeletal replacement prosthesis is coated or covered with a bioabsorbable polymer at selected sites on its surface so that bone affixation is preferentially delayed at these covered sites and bone adjacent to uncoated areas are not stress shielded. Thus, resorption is avoided. When the bioabsorbable polymer is gradually absorbed away, bone affixation takes place on the exposed surfaces, as needed.
Inventors
- 👤 James A. Davidson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:33
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/28; A61L27/34; A61F; A61F2/00; A61F2/02; A61F2/30; A61F2/30767; A61F2/30907; A61F2/32; A61F2/36; A61F2/38; A61F2/3662; A61F2/367; A61F2/3676; A61F2002/30001; A61F2002/30003; A61F2002/3006; A61F2002/30062; A61F2002/30064; A61F2002/30667; A61F2002/30677; A61F2/30721; A61F2/30734; A61F2002/30738; A61F2002/30919; A61F2/3609; A61F2002/3625; A61F2002/3631
Claims Analysis
Total Claims: 30
Claim 1
Independent Claim
114 words
An orthopedic prosthesis for insertion into an articulating joint space comprising: a) at least one component of a two-component joint system wherein each of said components are equipped with outer surfaces that cooperate with surfaces of the other component, the at least one component having surfaces that, upon initial implantation of said component, will be in contact with bone; and b) a bioabsorbable coating covering surface areas of the at least one component that will be in contact with the bone initially to provide load transfer over time from implant to bone by initially delaying bone attachment at the coated surfaces so that bone affixation occurs first at any uncoated surfaces of the prosthesis.
Claim 2
Dependent Claim
114 words
An orthopedic prosthesis for insertion into an articulating joint space comprising: a) at least one component of a two-component joint system wherein each of said components are equipped with outer surfaces that cooperate with surfaces of the other component, the at least one component having surfaces that, upon initial implantation of said component, will be in contact with bone; and b) a bioabsorbable coating covering surface areas of the at least one component that will be in contact with the bone initially to provide load transfer over time from implant to bone by initially delaying bone attachment at the coated surfaces so that bone affixation occurs first at any uncoated surfaces of the prosthesis.
Claim 3
Dependent Claim
14 words
The orthopedic prosthesis of claim 1 wherein said bioabsorbable coating comprises a bioabsorbable polymer.
Claim 4
Dependent Claim
28 words
The orthopedic prosthesis of claim 1 wherein said at least one component of the prosthesis comprises a bone tissue ingrowth receptive outer surface covered by said bioabsorbable coating.
Claim 5
Dependent Claim
27 words
The orthopedic prosthesis of claim 2 wherein said bioabsorbable polymer is a polymer selected from the group consisting of polylactide, polyglycolide, polydioxanone, polycaprolactone, hydroxybutyrate, and their copolymers.
Claim 6
Dependent Claim
41 words
The orthopedic prosthesis of claim 4, wherein a composition selected from the group consisting of osteogenic agents, bone morphogenic proteins, growth factors, antibiotics, anti-osteoporotics, and anti-inflammatory substances is incorporated within or beneath the bioabsorbable coating to control bone response with time.
Claim 7
Dependent Claim
38 words
The orthopedic prosthesis of claim 2 wherein the at least one component of the prosthesis outer surface is comprised of a material selected from the group consisting of a metal alloy, a ceramic, and an organic polymer composite.
Claim 8
Dependent Claim
38 words
The orthopedic prosthesis of claim 3 wherein the ingrowth receptive outer surface comprises beads or a mesh and the bioabsorbable coating is a polymer selected from the group consisting of polylactide, polyglycolide, polydioxanone, polycaprolactone, hydroxybutyrate, and their copolymers.
Claim 9
Dependent Claim
41 words
The orthopedic prosthesis of claim 7, wherein a composition selected from the group consisting of osteogenic agents, bone morphogenic proteins, growth factors, antibiotics, anti-osteoporotics, and anti-inflammatory substances is incorporated within or beneath the bioabsorbable coating to control bone response with time.
Claim 10
Dependent Claim
39 words
The orthopedic prosthesis of claim 1 wherein the bioabsorbable coating is a sheath comprising a thermoplastic, biocompatible polymer; said sheath covering at least a portion of the surface of said orthopedic prosthesis and firmly attached to the surface portion.
Claim 11
Dependent Claim
55 words
A hip prosthesis comprising: a) a prosthesis body having proximal and distal portions with outer surfaces; and b) a bioabsorbable coating at least partially covering the outer surface of the distal portion for initially delaying bone attachment at the coated surfaces so that bone affixation occurs first at any uncoated surfaces of the prosthesis body.
Claim 12
Dependent Claim
55 words
A hip prosthesis comprising: a) a prosthesis body having proximal and distal portions with outer surfaces; and b) a bioabsorbable coating at least partially covering the outer surface of the distal portion for initially delaying bone attachment at the coated surfaces so that bone affixation occurs first at any uncoated surfaces of the prosthesis body.
Claim 13
Dependent Claim
14 words
The hip prosthesis of claim 10 wherein said bioabsorbable coating comprises a bioabsorbable polymer.
Claim 14
Dependent Claim
22 words
The hip prosthesis of claim 10 wherein said prosthesis comprises a bone tissue ingrowth receptive outer surface covered by said bioabsorbable coating.
Claim 15
Dependent Claim
27 words
The hip prosthesis of claim 11 wherein said bioabsorbable polymer is a polymer selected from the group consisting of polylactide, polyglycolide, polydioxanone, polycaprolactone, hydroxybutyrate, and their copolymers.
Claim 16
Dependent Claim
31 words
The hip prosthesis of claim 13, wherein the coating further comprises a composition selected from the group consisting of osteogenic agents, bone morphogenic proteins, growth factors, antibiotics, anti-osteoporotics, and anti-inflammatory substances.
Claim 17
Dependent Claim
28 words
The hip prosthesis of claim 11 wherein the proximal end of the prosthesis body comprises a collar and the bioabsorbable coating covers at least part of the collar.
Claim 18
Dependent Claim
15 words
The hip prosthesis of claim 15 wherein the collar is comprised of a bioabsorbable polymer.
Claim 19
Dependent Claim
38 words
The hip prosthesis of claim 12 wherein the ingrowth receptive outer surface comprises beads or a mesh and the bioabsorbable coating is a polymer selected from the group consisting of polylactide, polyglycolide, polydioxanone, polycaprolactone, hydroxybutyrate, and their copolymers.
Claim 20
Dependent Claim
41 words
The hip prosthesis of claim 17, wherein a composition selected from the group consisting of osteogenic agents, bone morphogenic proteins, growth factors, antibiotics, anti-osteoporotics, and anti-inflammatory substances is incorporated within or beneath the bioabsorbable coating to control bone response with time.
Claim 21
Dependent Claim
39 words
The hip prosthesis of claim 10 wherein the bioabsorbable coating is a sheath comprising a thermoplastic, biocompatible polymer; said sheath covering at least a portion of the surface of said hip prosthesis and firmly attached to the surface portion.
Claim 22
Dependent Claim
79 words
A knee joint prosthesis comprising: a) a prosthesis having a femoral component with a first distal portion, and a tibial component with a second distal portion; b) a bioabsorbable coating, at least substantially covering the first and second distal portions of the prosthesis, for delaying initially bone attachment at the coated distal portions of the prosthesis so that affixation occurs first at proximal bone-contacting portions of the prosthesis while the bioabsorbable coating is gradually dissolved at said distal portions.
Claim 23
Dependent Claim
79 words
A knee joint prosthesis comprising: a) a prosthesis having a femoral component with a first distal portion, and a tibial component with a second distal portion; b) a bioabsorbable coating, at least substantially covering the first and second distal portions of the prosthesis, for delaying initially bone attachment at the coated distal portions of the prosthesis so that affixation occurs first at proximal bone-contacting portions of the prosthesis while the bioabsorbable coating is gradually dissolved at said distal portions.
Claim 24
Dependent Claim
18 words
The knee prosthesis of claim 20 wherein said coating comprises polylactide, polyglycolide, polydioxanone, polycaprolactone, hydroxybutyrate, and their copolymers.
Claim 25
Dependent Claim
41 words
The knee prosthesis of claim 21, wherein a composition selected from the group consisting of osteogenic agents, bone morphogenic proteins, growth factors, antibiotics, anti-osteoporotics, and anti-inflammatory substances is incorporated within or beneath the bioabsorbable coating to control bone response with time.
Claim 26
Dependent Claim
21 words
The knee prosthesis of claim 21, wherein said coating is on a fixation post of any other total joint replacement component.
Claim 27
Dependent Claim
14 words
The knee prosthesis of claim 23, wherein said fixation post is a tibial post.
Claim 28
Dependent Claim
13 words
The knee prosthesis of claim 21, wherein said coating is a pre-molded sheath.
Claim 29
Dependent Claim
25 words
The knee prosthesis of claim 25, wherein said bioabsorbable polymer coating was thermally transformed to allow said coating to be slipped onto the tibial post.
Claim 30
Dependent Claim
14 words
The orthopedic prosthesis of claim 20, wherein the bioabsorbable coating comprises a bioabsorbable polymer.
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| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1998-10-16 | 1999-04-17 | 1999-10-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-10-16 | 2003-04-17 | 2003-10-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-10-16 | 2007-04-17 | 2007-10-17 | $7700.00 | Window Closed / Lapsed |