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US5451589A
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Methods of inhibiting ovarian dysgenesis, delayed puberty, or sexual infantilism
Assignee: Eli Lilly and Co
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Filing: 1993-12-21
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Granted: 1995-09-19
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Expires: 2013-12-21
Abstract
Abstract A method of inhibiting ovarian dysgenesis, delayed puberty, or sexual infantilism comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R 1 and R 3 are independently hydrogen, --CH 3 , ##STR2## wherein Ar is optionally substituted phenyl; R 2 is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
Inventors
- 👤 Jeffrey A. Dodge
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 16:26
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/44; A61K31/445; A61K31/4523; A61K31/4535; A61K31/40; A61K31/4025; A61K31/55; A61P; A61P13/00; A61P13/02; A61P15/00; C; C07; C07D; C07D409/00; C07D409/02; C07D409/10
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
64 words
A method of inhibiting ovarian dysgenesis, comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR5## wherein R 1 and R 3 are independently hydrogen, --CH 3 , ##STR6## wherein Ar is optionally substituted phenyl; R 2 is selected from the group consisting of pyrrolidine, hexamthylenemino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
Claim 2
Independent Claim
64 words
A method of inhibiting ovarian dysgenesis, comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR5## wherein R 1 and R 3 are independently hydrogen, --CH 3 , ##STR6## wherein Ar is optionally substituted phenyl; R 2 is selected from the group consisting of pyrrolidine, hexamthylenemino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
Claim 3
Dependent Claim
13 words
The method of claim 1 wherein said compound is the hydrochloride salt thereof.
Claim 4
Dependent Claim
14 words
The method of claim 1 wherein said compound is ##STR7## or its hydrochloride salt.
Claim 5
Dependent Claim
14 words
The method of claim 1 wherein said human is under the age of eighteen.
Claim 6
Dependent Claim
13 words
The method of claim 1 wherein said human is also administered a progestin.
References Cited (Backward Citations)
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Cited
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Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-09-18 | 1999-03-20 | 1999-09-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-09-18 | 2003-03-20 | 2003-09-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-09-18 | 2007-03-20 | 2007-09-19 | $7700.00 | Window Closed / Lapsed |