US5415162A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Multi-dose dry powder inhalation device
Assignee: GlaxoSmithKline LLC
•
Filing: 1994-01-18
•
Granted: 1995-05-16
•
Expires: 2014-01-18
Abstract
Abstract A breath-actuated dry powder medicament inhalator device having a housing and a conduit mounted within the housing defining an air passageway therethrough having an aperture in the sidewall thereof. A blister-type strip of sealed containers arranged in a matrix of rows and columns wherein the columns extend generally diagonally to the longitudinal axis of the strip is secured in a two-piece cage adapted for being rotatably mounted around the conduit of the inhalator device. Advancement means are provided for rotatably moving the two-piece cage and blister strip contained thereby in a generally helical pathway relative to the conduit so as to successively advance each of the sealed containers of the blister strip into registration with the conduit aperture. Piercing means are associated with the housing for successively piercing each of the sealed containers of the blister strip when advanced into registration with the conduit aperture by the advancement means in order to introduce the dry powder compound contained therein into the air passageway of the conduit.
Inventors
- 👤 Robert A. Casper
- 👤 Malcolm E. Taylor
- 👤 Frank A. Leith
- 👤 David H. Leith
- 👤 Maryanne G. Boundy
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 14:01
CPC Classifications
A; A61; A61M; A61M15/00; A61M15/0028; A61M15/0045; A61M15/003; A61M15/0033; A61M15/0035; A61M15/0046; A61M15/005; A61M2202/00; A61M2202/06; A61M2202/064
Claims Analysis
Total Claims: 36
Claim 1
Independent Claim
279 words
A portable device for the inhalation of a predetermined amount of dry powder compound from a blister-type strip of sealed containers, comprising: (a) a housing; (b) a conduit mounted within said housing defining an air passageway therethrough and having an air inlet end and an air exit end and an aperture extending through a side wall of said conduit therebetween, said air exit end being adapted for insertion into the mouth of a user; (c) a blister-type strip of sealed containers wherein said sealed containers are arranged in a matrix of rows and columns and said columns extend generally diagonally to the longitudinal axis of said strip; (d) cage means for rotatably mounting said blister-type strip of sealed containers of dry powder compound in a cylindrical configuration around said conduit wherein said rows of said blister-type strip extend generally parallel to the longitudinal axis of said conduit; (e) advancement means associated with said housing for rotatably moving said cage means in a generally helical pathway relative to said conduit so as to successively advance each of said sealed containers of said blister-type strip into registration with the aperture of said conduit; and (f) piercing means associated with said housing for piercing each of said sealed containers of said blister strip when advanced into registration with the aperture of said conduit so as to introduce said dry powder compound therein into the air passageway of said conduit; whereby said blister-type strip will be rotatably and axially moved relative to said conduit as said sealed containers thereof are advanced along said helical pathway and successively pierced for administration of a predetermined amount of said dry powder compound from said inhalation device.
Claim 2
Dependent Claim
279 words
A portable device for the inhalation of a predetermined amount of dry powder compound from a blister-type strip of sealed containers, comprising: (a) a housing; (b) a conduit mounted within said housing defining an air passageway therethrough and having an air inlet end and an air exit end and an aperture extending through a side wall of said conduit therebetween, said air exit end being adapted for insertion into the mouth of a user; (c) a blister-type strip of sealed containers wherein said sealed containers are arranged in a matrix of rows and columns and said columns extend generally diagonally to the longitudinal axis of said strip; (d) cage means for rotatably mounting said blister-type strip of sealed containers of dry powder compound in a cylindrical configuration around said conduit wherein said rows of said blister-type strip extend generally parallel to the longitudinal axis of said conduit; (e) advancement means associated with said housing for rotatably moving said cage means in a generally helical pathway relative to said conduit so as to successively advance each of said sealed containers of said blister-type strip into registration with the aperture of said conduit; and (f) piercing means associated with said housing for piercing each of said sealed containers of said blister strip when advanced into registration with the aperture of said conduit so as to introduce said dry powder compound therein into the air passageway of said conduit; whereby said blister-type strip will be rotatably and axially moved relative to said conduit as said sealed containers thereof are advanced along said helical pathway and successively pierced for administration of a predetermined amount of said dry powder compound from said inhalation device.
Claim 3
Dependent Claim
29 words
A portable device according to claim 1 wherein said housing defines a generally cylindrical shape having a longitudinal axis extending generally coaxially with the longitudinal axis of said conduit.
Claim 4
Dependent Claim
37 words
A portable device according to claim 2 wherein the inside surface of said, housing is radially spaced apart from the outside surface of said conduit so as to define a space therebetween for receiving said cage means.
Claim 5
Dependent Claim
32 words
A portable device according to claim 2 wherein said housing defines an opening around the circumference of said air inlet end of said conduit so as to receive said cage means therethrough.
Claim 6
Dependent Claim
54 words
A portable device according to claim 1 wherein said air passageway defined within said conduit comprises a venturi in the medial portion of the length thereof, and said aperture extending through said conduit has one end on the outside surface of said conduit and the other end opens into said venturi of said conduit.
Claim 7
Dependent Claim
27 words
A portable device according to claim 5 wherein said aperture of said conduit includes an enlarged swirl chamber between said inlet end and said outlet end thereof.
Claim 8
Dependent Claim
49 words
A portable device according to claim 1 wherein said blister-type strip comprises 15 rows of sealed containers extending generally normally to the longitudinal axis of said strip and 4 columns of sealed containers each extending generally parallel to each other and diagonally to the longitudinal axis of said strip.
Claim 9
Dependent Claim
49 words
A portable device according to claim 1 wherein said blister-type strip comprises 15 rows of sealed containers extending generally normally to the longitudinal axis of said strip and 8 columns of sealed containers each extending generally parallel to each other and diagonally to the longitudinal axis of said strip.
Claim 10
Dependent Claim
144 words
A portable device according to claim 1 wherein said cage means comprises: a first flexible strip defining a plurality of cavities therein so that when said blister-type strip is placed in overlying relationship thereto said sealed containers of said blister-type strip will each nest in a corresponding one of said plurality of cavities of said first strip; a second flexible strip defining a plurality of apertures therein so that when said second strip is placed in overlying relationship to said blister-type strip and said first strip, said apertures of said second strip will each be in vertical registration with a corresponding one of said sealed containers of said blister-type strip; said first and second strips being adapted to be secured together as an assembly with said blister-type strip positioned therebetween and said assembly then formed into a cylindrical configuration for positioning around said conduit.
Claim 11
Dependent Claim
13 words
A portable device according to claim 9 wherein said cage means is disposable.
Claim 12
Dependent Claim
110 words
A portable device according to claim 1 wherein said advancement means comprises: a plurality of protuberances arranged in a helix on the outside surface of said conduit defining said air passageway and serving to guide the movement of said cage around said conduit along the helical pathway defined by said protuberances; and ratchet means reciprocatingly mounted to said housing and adapted to cooperatively engage said cage means and to rotate said cage means about said conduit a sufficient distance to advance the next successive row of sealed containers of said blister-type strip such that one of said sealed containers thereof will be in registration with the aperture of said conduit.
Claim 13
Dependent Claim
43 words
A portable device according to claim 1 wherein said piercing means comprises a needle element adapted for vertical movement from a retracted position to an extended position wherein said needle element pierces said sealed container in registration with the aperture of said conduit.
Claim 14
Dependent Claim
43 words
A portable device according to claim 12 wherein said piercing means comprises an air vent therein to allow for air entry into said air passageway of said conduit from outside said housing subsequent to piercing of said sealed container by said needle element.
Claim 15
Dependent Claim
271 words
In a portable device for the inhalation of a predetermined amount of dry powder compound and characterized by a housing; an air passageway provided within said housing having an air inlet end, an air exit end adapted for insertion into the mouth of a user, and an aperture through a side wall at a predetermined location along the length thereof; and piercing means associated with said housing for piercing a sealed container of said dry powder compound when positioned in registration with the aperture of said air passageway so as to introduce said dry powder compound into the air passageway, the improvement comprising: a blister-type strip of sealed containers of dry powder compound arranged in a matrix of rows and columns wherein said columns extend generally parallel to each other and generally diagonally to the longitudinal axis of said strip; cage means for rotatably mounting said blister-type strip of sealed containers in a cylindrical configuration within said housing and around said air passageway wherein said rows of said blister-type strip extend generally parallel to the longitudinal axis of said air passageway; and advancement means associated with said housing for rotatably moving said cage means in a generally helical pathway relative to said air passageway so as to successively advance each of said sealed containers of said blister-type strip into registration with the aperture of said air passageway; whereby said blister-type strip will be rotatably and axially moved relative to said air passageway as said sealed containers thereof are advanced along said helical pathway and successively pierced for administration of a predetermined amount of said dry powder compound from said inhalation device.
Claim 16
Dependent Claim
271 words
In a portable device for the inhalation of a predetermined amount of dry powder compound and characterized by a housing; an air passageway provided within said housing having an air inlet end, an air exit end adapted for insertion into the mouth of a user, and an aperture through a side wall at a predetermined location along the length thereof; and piercing means associated with said housing for piercing a sealed container of said dry powder compound when positioned in registration with the aperture of said air passageway so as to introduce said dry powder compound into the air passageway, the improvement comprising: a blister-type strip of sealed containers of dry powder compound arranged in a matrix of rows and columns wherein said columns extend generally parallel to each other and generally diagonally to the longitudinal axis of said strip; cage means for rotatably mounting said blister-type strip of sealed containers in a cylindrical configuration within said housing and around said air passageway wherein said rows of said blister-type strip extend generally parallel to the longitudinal axis of said air passageway; and advancement means associated with said housing for rotatably moving said cage means in a generally helical pathway relative to said air passageway so as to successively advance each of said sealed containers of said blister-type strip into registration with the aperture of said air passageway; whereby said blister-type strip will be rotatably and axially moved relative to said air passageway as said sealed containers thereof are advanced along said helical pathway and successively pierced for administration of a predetermined amount of said dry powder compound from said inhalation device.
Claim 17
Dependent Claim
46 words
A portable device according to claim 14 wherein said air passageway is defined by a conduit and the inside surface of said housing is radially spaced apart from the outside surface of said conduit so as to define a space therebetween for receiving said cage means.
Claim 18
Dependent Claim
32 words
A portable device according to claim 15 wherein said housing defines an opening around the circumference of said air inlet end of said conduit so as to receive said cage means therethrough.
Claim 19
Dependent Claim
49 words
A portable device according to claim 14 wherein said blister-type strip comprises 15 rows of sealed containers extending generally normally to the longitudinal axis of said strip and 4 columns of sealed containers each extending generally parallel to each other and diagonally to the longitudinal axis of said strip.
Claim 20
Dependent Claim
49 words
A portable device according to claim 14 wherein said blister-type strip comprises 15 rows of sealed containers extending generally normally to the longitudinal axis of said strip and 8 columns of sealed containers each extending generally parallel to each other and diagonally to the longitudinal axis of said strip.
Claim 21
Dependent Claim
144 words
A portable device according to claim 15 wherein said cage means comprises: a first flexible strip defining a plurality of cavities therein so that when said blister-type strip is placed in overlying relationship thereto said sealed containers of said blister-type strip will each nest in a corresponding one of said plurality of cavities of said first strip; a second flexible strip defining a plurality of apertures therein so that when said second strip is placed in overlying relationship thereto said blister-type strip and said first strip, said apertures of said second strip will each be in vertical registration with a corresponding one of said sealed containers of said blister-type strip; said first and second strips being adapted to be secured together as an assembly with said blister-type strip positioned therebetween and said assembly then formed into a cylindrical configuration for positioning around said conduit.
Claim 22
Dependent Claim
13 words
A portable device according to claim 19 wherein said cage means is disposable.
Claim 23
Dependent Claim
106 words
A portable device according to claim 15 wherein said advancement means comprises: a plurality of protuberances arranged in a helix on the outside surface of said conduit and serve to guide the movement of said cage around said conduit along the helical pathway defined by said protuberances; ratchet means reciprocatingly mounted to said housing and adapted to cooperatively engage said cage means and to rotate said cage means about said conduit a sufficient distance to advance the next successive row of sealed containers of said blister-type strip such that one of said sealed containers thereof will be in registration with the aperture of said air passageway.
Claim 24
Dependent Claim
59 words
A portable device according to claim 21 wherein said advancement means successively helically advances said cage means and blister-type strip contained thereby from an innermost first position within the housing of said portable inhalation device to a second outermost position wherein at least a portion of said cage means and blister-type strip contained thereby are outside of the housing.
Claim 25
Dependent Claim
238 words
A portable device for the inhalation of a predetermined amount of dry powder compound from a blister-type strip of sealed containers, comprising: (a) a housing; (b) a conduit mounted within said housing defining an air passageway therethrough and having an air inlet end and an air exit end and an aperture extending through a side wall of said conduit therebetween, said air exit end being adapted for insertion into the mouth of a user; (c) a blister-type strip of sealed containers wherein said sealed containers are arranged in a matrix of rows and columns; (d) cage means for rotatably mounting said blister-type strip of sealed containers of dry powder compound in a cylindrical configuration around said conduit; (e) advancement means associated with said housing for rotatably moving said cage means relative to said conduit so as to successively advance each of said sealed containers of said blister-type strip into registration with the aperture of said conduit; and (f) piercing means associated with said housing for piercing each of said sealed containers of said blister strip when advanced into registration with the aperture of said conduit so as to introduce said dry powder compound therein into the air passageway of said conduit; whereby said blister-type strip will be moved relative to said conduit as said sealed containers thereof are advanced and successively pierced for periodic administration of a predetermined amount of said dry powder compound from said inhalation device.
Claim 26
Dependent Claim
238 words
A portable device for the inhalation of a predetermined amount of dry powder compound from a blister-type strip of sealed containers, comprising: (a) a housing; (b) a conduit mounted within said housing defining an air passageway therethrough and having an air inlet end and an air exit end and an aperture extending through a side wall of said conduit therebetween, said air exit end being adapted for insertion into the mouth of a user; (c) a blister-type strip of sealed containers wherein said sealed containers are arranged in a matrix of rows and columns; (d) cage means for rotatably mounting said blister-type strip of sealed containers of dry powder compound in a cylindrical configuration around said conduit; (e) advancement means associated with said housing for rotatably moving said cage means relative to said conduit so as to successively advance each of said sealed containers of said blister-type strip into registration with the aperture of said conduit; and (f) piercing means associated with said housing for piercing each of said sealed containers of said blister strip when advanced into registration with the aperture of said conduit so as to introduce said dry powder compound therein into the air passageway of said conduit; whereby said blister-type strip will be moved relative to said conduit as said sealed containers thereof are advanced and successively pierced for periodic administration of a predetermined amount of said dry powder compound from said inhalation device.
Claim 27
Dependent Claim
29 words
A portable device according to claim 23 wherein said housing defines a generally cylindrical shape having a longitudinal axis extending generally coaxially with the longitudinal axis of said conduit.
Claim 28
Dependent Claim
37 words
A portable device according to claim 24 wherein the inside surface of said housing is radially spaced apart from the outside surface of said conduit so as to define a space therebetween for receiving said cage means.
Claim 29
Dependent Claim
32 words
A portable device according to claim 24 wherein said housing defines an opening around the circumference of said air inlet end of said conduit so as to receive said cage means therethrough.
Claim 30
Dependent Claim
54 words
A portable device according to claim 23 wherein said air passageway defined within said conduit comprises a venturi in the medial portion of the length thereof, and said aperture extending through said conduit has one end on the outside surface of said conduit and the other end opens into said venturi of said conduit.
Claim 31
Dependent Claim
27 words
A portable device according to claim 27 wherein said aperture of said conduit includes an enlarged swirl chamber between said inlet end and said outlet end thereof.
Claim 32
Dependent Claim
144 words
A portable device according to claim 23 wherein said cage means comprises: a first flexible strip defining a plurality of cavities therein so that when said blister-type strip is placed in overlying relationship thereto said sealed containers of said blister-type strip will each nest in a corresponding one of said plurality of cavities of said first strip; a second flexible strip defining a plurality of apertures therein so that when said second strip is placed in overlying relationship to said blister-type strip and said first strip, said apertures of said second strip will each be in vertical registration with a corresponding one of said sealed containers of said blister-type strip; said first and second strips being adapted to be secured together as an assembly with said blister-type strip positioned therebetween and said assembly then formed into a cylindrical configuration for positioning around said conduit.
Claim 33
Dependent Claim
13 words
A portable device according to claim 29 wherein said cage means is disposable.
Claim 34
Dependent Claim
95 words
A portable device according to claim 23 wherein said advancement means comprises: a plurality of protuberances on the outside surface of said conduit defining said air passageway and serving to guide the movement of said cage around said conduit along a pathway defined by said protuberances; and ratchet means reciprocatingly mounted to said housing and adapted to cooperatively engage said cage means and to rotate said cage means about said conduit a sufficient distance to advance said blister-type strip such that successive sealed containers thereof will be in registration with the aperture of said conduit.
Claim 35
Dependent Claim
43 words
A portable device according to claim 23 wherein said piercing means comprises a needle element adapted for vertical movement from a retracted position to an extended position wherein said needle element pierces said sealed container in registration with the aperture of said conduit.
Claim 36
Dependent Claim
43 words
A portable device according to claim 32 wherein said piercing means comprises an air vent therein to allow for air entry into said air passageway of said conduit from outside said housing subsequent to piercing of said sealed container by said needle element.
References Cited (Backward Citations)
US3967761A
Cited
US5192548A
Cited
US5207217A
Cited
US5337740A
Cited
US5161524A
Cited
US5301666A
Cited
US5239993A
Cited
US5349947A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-05-15 | 1998-11-14 | 1999-05-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-05-15 | 2002-11-14 | 2003-05-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-05-15 | 2006-11-14 | 2007-05-16 | $7700.00 | Window Closed / Lapsed |