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US5402782A Expired / Lapsed US ⏱️ 0.0 years remaining

Apparatus and method for noninvasive chemical analysis

Assignee: University of Kentucky Research Foundation
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Filing: 1993-03-05
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Granted: 1995-04-04
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Expires: 2013-03-05
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Abstract

Abstract A method and apparatus are provided for magnetohydrodynamic acoustic-resonance, near-IR spectroscopy. The method includes a step of applying to a subject under study a magnetic field having a strength between 2,00-10,000 gauss, near-IR radiation having a wavelength between 800-3,000 nm and an acoustic wave having a frequency between 10 khz-1 Mhz. The method also includes the steps of inducing vibration of ions in the magnetic field and detecting an electric wave generated magnetohydrodynamically by the acoustic wave induced vibration of the ions. Next is the collecting of the electrical, acoustical and near-IR spectra and the analyzing of the collected spectra. The spectra is analyzed in a hyphenated, multidimensional fashion.

Inventors

  • 👤 Robert A. Lodder

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 19:14
CPC Classifications
G; G01; G01N; G01N29/00; G01N29/22; G01N29/24; G01N29/2431; G01N21/00; G01N21/17; G01N21/25; G01N21/31; G01N21/35; G01N21/3563; G01N21/359; G01N29/04; G01N29/06; G01N29/0609; G01N29/2418

Claims Analysis

Total Claims: 21
Claim 1
Independent Claim 77 words
A method for magnetohydrodynamic, acoustic-resonance near-IR spectroscoy, comprising the steps of: simultaneously applying to a subject under study (1) a magnetic field, (2) near-IR radiation and (3) an acoustic wave; generating electrical spectra magnetohydrodynamically by the acoustic wave induced vibration of ions in the magnetic field; collecting electrical, acoustical and near I-R spectra emitted from the subject under study as a result of the simultaneously applied magnetic field, near-IR radiation and acoustic wave; analyzing the collected spectra.
Claim 2
Independent Claim 77 words
A method for magnetohydrodynamic, acoustic-resonance near-IR spectroscoy, comprising the steps of: simultaneously applying to a subject under study (1) a magnetic field, (2) near-IR radiation and (3) an acoustic wave; generating electrical spectra magnetohydrodynamically by the acoustic wave induced vibration of ions in the magnetic field; collecting electrical, acoustical and near I-R spectra emitted from the subject under study as a result of the simultaneously applied magnetic field, near-IR radiation and acoustic wave; analyzing the collected spectra.
Claim 3
Dependent Claim 18 words
The method set forth in claim 1, wherein said electrical, acoustical and near-IR spectra are all collected simultaneously.
Claim 4
Dependent Claim 30 words
The method set forth in claim 2, wherein said magnetic field, near-IR radiation and acoustic wave are all applied to the subject under study in directions orthogonal to one another.
Claim 5
Dependent Claim 21 words
The method set forth in claim 3, wherein said electrical, acoustical and near-IR spectra are collected in a hyphenated multidimensional fashion.
Claim 6
Dependent Claim 21 words
The method set forth in claim 2, wherein said electrical, acoustic and near-IR spectra are collected in a hyphenated multidimensional fashion.
Claim 7
Dependent Claim 30 words
The method set forth in claim 1, wherein said magnetic field, near-IR radiation and acoustic wave are all applied to the subject under study in directions orthogonal to one another.
Claim 8
Dependent Claim 21 words
The method set forth in claim 6, wherein said electrical, acoustical and near-IR spectra are collected in a hyphenated multidimensional fashion.
Claim 9
Dependent Claim 22 words
The method set forth in claim 1, wherein said electrical, acoustical and near-IR spectra are collected in a hyphenated , multidimensional fashion.
Claim 10
Independent Claim 108 words
A method for magnetohydrodynamic, acoustic-resonance, near-IR spectroscopy, comprising the steps of: simultaneously applying to a subject under study (1) a magnetic field having a strength between 2,000-10,000 gauss, (2) near-IR radiation having a wavelength between 800-3,000 nm and (3) an acoustic wave having a frequency between 10 khz-1 Mhz; inducing vibration of ions in the magnetic field by application of the acoustic wave and generating electrical spectra magnetohydrodynamically by the acoustic wave induced vibration of said ions; collecting electrical, acoustical and near-IR spectra emitted from the subject under study as a result of the simultaneously applied magnetic field, near-IR radiation and acoustic wave; and analyzing the collected spectra.
Claim 11
Independent Claim 108 words
A method for magnetohydrodynamic, acoustic-resonance, near-IR spectroscopy, comprising the steps of: simultaneously applying to a subject under study (1) a magnetic field having a strength between 2,000-10,000 gauss, (2) near-IR radiation having a wavelength between 800-3,000 nm and (3) an acoustic wave having a frequency between 10 khz-1 Mhz; inducing vibration of ions in the magnetic field by application of the acoustic wave and generating electrical spectra magnetohydrodynamically by the acoustic wave induced vibration of said ions; collecting electrical, acoustical and near-IR spectra emitted from the subject under study as a result of the simultaneously applied magnetic field, near-IR radiation and acoustic wave; and analyzing the collected spectra.
Claim 12
Dependent Claim 32 words
The method set forth in claim 9, wherein analyzing of the collected near-IR spectra is performed by equal weighting of wavelengths across a near-IR radiation spectrum of between at least 1500-2100 nm.
Claim 13
Dependent Claim 31 words
The method set forth in claim 10, wherein said magnetic field, near-IR radiation and acoustic wave are all simultaneously applied to said subject under study in directions orthogonal to one another.
Claim 14
Dependent Claim 21 words
The method set forth in claim 11, wherein said electrical, acoustical, near-IR spectra are collected simultaneously in a hyphenated, multidimensional fashion.
Claim 15
Dependent Claim 32 words
The method set forth in claim 9, wherein analyzing of the collected near-IR spectra is performed by equal weighting of wavelengths across a near-IR radiation spectrum of between at least 800-3000 nm.
Claim 16
Dependent Claim 31 words
The method set forth in claim 13, wherein said magnetic field, near-IR radiation and acoustic wave are all simultaneously applied to said subject under study in directions orthogonal to one another.
Claim 17
Dependent Claim 21 words
The method set forth in claim 14, wherein said electrical, acoustical, near-IR spectra are collected simultaneously in a hyphenated, multidimensional fashion.
Claim 18
Dependent Claim 31 words
The method set forth in claim 9, wherein said magnetic field, near-IR radiation and acoustic wave are all simultaneously applied to said subject under study in directions orthogonal to one another.
Claim 19
Independent Claim 109 words
An apparatus for performing magnetohydrodynamic, acoustic-resonance, near-IR spectroscopy of a subject under study, comprising: means for producing a magnetic field applied to said subject under study; means for irradiating said subject under study with near-IR radiation; means for producing a tunable acoustic wave that is transmitted into the subject under study; means for detecting and collecting electrical spectra generated magnetohydrodynamically by the acoustic-wave induced vibration of ions in the magnetic field whereby ion concentration may be noninvasively deduced; means for collecting acoustical and near-IR spectra emitted from the subject under study as a result of the applied, near-IR radiation and acoustic wave; and means for analyzing the collected spectra.
Claim 20
Independent Claim 109 words
An apparatus for performing magnetohydrodynamic, acoustic-resonance, near-IR spectroscopy of a subject under study, comprising: means for producing a magnetic field applied to said subject under study; means for irradiating said subject under study with near-IR radiation; means for producing a tunable acoustic wave that is transmitted into the subject under study; means for detecting and collecting electrical spectra generated magnetohydrodynamically by the acoustic-wave induced vibration of ions in the magnetic field whereby ion concentration may be noninvasively deduced; means for collecting acoustical and near-IR spectra emitted from the subject under study as a result of the applied, near-IR radiation and acoustic wave; and means for analyzing the collected spectra.
Claim 21
Dependent Claim 32 words
The apparatus set forth in claim 17, including means for applying said magnetic field, near-IR radiation and acoustic wave to said subject under study simultaneously and in directions orthogonal to one another.

References Cited (Backward Citations)

US4801552A Cited
US4765179A Cited
US4767719A Cited
US4935875A Cited
US5064638A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1998-04-03 1998-10-03 1999-04-04 $2000.00 Window Closed / Lapsed
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